Las ocratoxinas son metabolitos fúngicos que están presentes en una gran variedad de alimentos y sus subproductos. La nefrotoxicidad es su principal efecto tóxico, relacionado a su vez con distintos síndromes clínicos como la necrosis tubular o la nefropatía de los Balcanes. La mayor parte de la in...
The aim of this study was to evaluate the effects of single oral doses of D-005 (a lipid extract obtained from the fruit oil of Acrocomia crispa) on LPS-induced acute lung injury (ALI) in mice. D-005 batch composition was: lauric (35.8%), oleic (28.4%), myristic (14.2%), palmitic (8.9%), stearic (3.3%), ...
Arecaceae,
Extractos Vegetales/administración & dosificación,
Ácidos Grasos/análisis,
Lipopolisacáridos/efectos adversos,
Lesión Pulmonar Aguda/prevención & control,
Lesión Pulmonar Aguda/inducido químicamente,
Cromatografía de Gases,
Administración Oral,
Extractos Vegetales/química,
Frutas,
Pulmón/efectos de los fármacos
The aim of this study was to evaluate the concentration and chemical composition of the essential oil the leaves of basil cultivars and hybrids cultivated in different cropping seasons: dry season and rainy season. The variables evaluated were the content and composition of essential oils in the two seas...
O objetivo foi avaliar o efeito do tratamento periodontal não cirúrgico, após 1 ano, na expressão salivar dos marcadores do metabolismo ósseo: TNF-α, SOST, PTH, OPG, OPN, OC, Leptina, IL-6, IL-1β e FGF-23; em pacientes com periodontite crônica generalizada. Participaram deste estudo 15 pacientes ...
Abstract INTRODUCTION: Antimicrobial resistance has been reported in the drugs used for the treatment of typhoid fever. The immunomodulatory substance β-glucan can be used as an alternative therapy as it potentiates host immunity. The aims of this study are to observe the effect of Candida albicans...
Linfocitos T CD4-Positivos/microbiología,
Linfocitos T CD8-positivos/microbiología,
Candida albicans/química,
Pared Celular,
Ciprofloxacina,
Modelos Animales de Enfermedad,
Inmunidad Celular/inmunología,
Inmunoglobulina A Secretora,
Intestinos/microbiología,
Hígado/microbiología,
Ratones,
Ratones Endogámicos BALB C,
Pruebas de Sensibilidad Microbiana,
Salmonella typhimurium/efectos de los fármacos,
Fiebre Tifoidea/microbiología,
beta-Glucanos/farmacología
Abstract Purpose: To analyze, histomorphologically, the influence of the geometry of nanostructured hydroxyapatite and alginate (HAn/Alg) composites in the initial phase of the bone repair. Methods: Fifteen rats were distributed to three groups: MiHA - bone defect filled with HAn/Alg microspheres; GrHA...
Alginatos/administración & dosificación,
Alginatos/química,
Materiales Biocompatibles/administración & dosificación,
Materiales Biocompatibles/química,
Regeneración Ósea/efectos de los fármacos,
Regeneración Ósea/fisiología,
Durapatita/administración & dosificación,
Durapatita/química,
Nanoestructuras/administración & dosificación,
Nanoestructuras/química,
Ratas Wistar,
Espectrofotometría Infrarroja
Mammadov, Renad;
Suleyman, Bahadir;
Altuner, Durdu;
Demirci, Elif;
Cetin, Nihal;
Yilmaz, Adnan;
Baykal, Huseyin;
Alpcan, Hilal;
Turumtay, Emine Akyuz;
Suleyman, Halis.
Abstract Purpose: To investigate the effects of the EtOAc extract of U. longissima which is uninvestigated previously on esophagogastric cancer induced in rats with N-methyl-N-nitro-N-nitrosoguanidin (MNNG). Methods: The anticancer activity of EtOAc extract of U. longissima was examined in the esopha...
Abstract Purpose: To evaluate the healing potential of the Ximenia americana hydroalcoholic extract in 10% cream in excisional wound models in rats. Methods: Sixty male adults Wistar rats were submitted to skin and subcutaneous tissue surgery in the right and left thoracic regions, divided into three...
Abstract Purpose Coleus forskohlii Briq., a medicinal plant originally from India, has been indicated against heart disease, expiratory disorders, convulsions, and hepatic changes, among others. In view of the broad pharmacological potential of the plant and the scarce information about its effects, the...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Aspartato Aminotransferasas/sangre,
Biomarcadores/sangre,
Hepatectomía/métodos,
Hepatocitos/efectos de los fármacos,
Hiperplasia/tratamiento farmacológico,
Hígado/efectos de los fármacos,
Hígado/patología,
Hígado/cirugía,
Extractos Vegetales/administración & dosificación,
Plectranthus/química
