ABSTRACT Objective: To determine the relationships that smoking history has with inflammatory markers, metabolic markers, body composition, muscle strength, and cardiopulmonary capacity in current smokers. Methods: This was a cross-sectional study involving 65 smokers (age range: 18-60 years). On three...
Biomarcadores/análisis,
Biomarcadores/metabolismo,
Composición Corporal/efectos de los fármacos,
Índice de Masa Corporal,
Capacidad Cardiovascular,
Estudios Transversales,
Inflamación/metabolismo,
Monocitos/metabolismo,
Fuerza Muscular/efectos de los fármacos,
Fumadores,
Fumar/efectos adversos,
Fumar/metabolismo,
Triglicéridos/sangre,
Circunferencia de la Cintura
Abstract Background The human skin is an extremely sophisticated and evolved organ that covers the whole body. External agents or the patient's own diseases can cause skin injuries that can challenge healthcare professionals and impose high social, economic and emotional costs. Objectives To evaluate t...
Salmonellosis is a relevant public health threat worldwide. Reptiles are commonly involved in human cases. A microbiological survey was conducted from August to October 2018 to isolate Salmonella bacteria and de-termine if they were resistant to regularly used antibiotics in eight species of pet turtles ...
The essential oil of Laurus nobilis L. was used to test their antinociceptive efficacy. It was applied intraperitoneally (i.p.) to rats subjected to a nociception test (C reflex and spinal wind-up). The results showed that the essential oil applied at higher doses (0.06 mg/Kg) causes a complete aboliti...
Passos, Bruno Goulart;
Rangel, Leonardo da Silva;
Albuquerque, Ricardo Diego Duarte Galhardo de;
Caldas, Gabriel Rocha;
Santos, Marcelo Guerra;
Esteves, Ricardo dos Santos;
Milton, Flora Aparecida;
Neves, Francisco de Assis Rocha;
Ruppelt, Bettina Monika;
Santos, José Augusto Albuquerque dos;
Faria, Robson Xavier;
Rocha, Leandro.
The aim of this work was to evaluate the potential of the essential oil (EO) from Ocotea pulchella leaves as an alternative in the control of schistosomiasis. It was tested O. pulchella EO nanoformulation to assess its activity against adult Biomphalaria glabrata, their spawning and Schistossoma mansoni...
Ocotea/química,
Aceites Volátiles/administración & dosificación,
Aceites Volátiles/química,
Moluscos/efectos de los fármacos,
Esquistosomiasis/prevención & control,
Aceites Volátiles/farmacología,
Control Biológico de Vectores,
Derivados de Alilbenceno/análisis,
Dioxolanos/análisis,
Sesquiterpenos de Germacrano/análisis,
Monoterpenos Bicíclicos/análisis,
Cromatografía de Gases,
Emulsiones/administración & dosificación,
Emulsiones/farmacología,
Interacciones Hidrofóbicas e Hidrofílicas,
Biomphalaria/efectos de los fármacos,
Cercarias/efectos de los fármacos,
Schistosoma mansoni/efectos de los fármacos
Wijesinghe, Gayan Kanchana;
Maia, Flávia Camila;
de Oliveira, Thaís Rossini;
de Feiria, Simone N Busato;
Joia, Felipe;
Barbosa, Janaina Priscila;
Boni, Giovana Cláudia;
Sardi, Janaina de Cássia Orlandi;
Rosalen, Pedro Luiz;
Höfling, José Francisco.
BACKGROUND Essential oils (EO) extracted from Cinnamomum verum has been used as an antimicrobial agents for centuries. The effects of C. verum leaf oil against virulence of microorganisms is not well studied yet. OBJECTIVES This study evaluates the effect of C. verum leaf oil against three virulence f...
BACKGROUND Carrion's disease (CD) is a neglected biphasic illness caused by Bartonella bacilliformis, a Gram-negative bacteria found in the Andean valleys. The spread of resistant strains underlines the need for novel antimicrobials against B. bacilliformis and related bacterial pathogens. OBJECTIVE T...
Giardiasis is an infectious disease caused by Giardia duodenalis. The pro-drug metronidazole (MTZ) is the first-line treatment for giardiasis. Parasite's proteins as pyruvate:ferredoxin oxidoreductase (PFOR), ferredoxin (Fd), nitroreductase-1 (NR-1) and thioredoxin reductase (TrxR) participate in MTZ act...
BACKGROUND Aedes aegypti is the primary transmitter of several arbovirus with great impact in human health. Controlling vector mosquitoes is an essential and complex task. One promising control method is to use mosquitoes as a vehicle to disseminate tiny particles of juvenile-killing insecticides, such a...
Luchi, T C;
Coelho, P M;
Cordeiro, J P;
Assis, A L E M;
Nogueira, B V;
Marques, V B;
dos Santos, L;
Lima-Leopoldo, A P;
Lunz, W;
Leopoldo, A S.
Nitric oxide (NO) inhibition by high-dose NG-nitro-L-arginine methyl ester (L-NAME) is associated with several detrimental effects on the cardiovascular system. However, low-dose L-NAME increases NO synthesis, which in turn induces physiological cardiovascular benefits, probably by activating a protectiv...
Adiposidad,
Peso Corporal/fisiología,
Calcio/análisis,
Inhibidores Enzimáticos/administración & dosificación,
Inhibidores Enzimáticos/farmacología,
Hemodinámica,
Modelos Animales,
Actividad Motora/fisiología,
Contracción Miocárdica/efectos de los fármacos,
Miocardio/patología,
Miocitos Cardíacos/efectos de los fármacos,
Miocitos Cardíacos/fisiología,
NG-Nitroarginina Metil Éster/administración & dosificación,
NG-Nitroarginina Metil Éster/farmacología,
Óxido Nítrico Sintasa/efectos de los fármacos,
Óxido Nítrico Sintasa/metabolismo,
Condicionamiento Físico Animal/fisiología,
Ratas Wistar,
Presión Ventricular/efectos de los fármacos
