Chagas, Diego Cipriano;
Barros-Oliveira, Maria da Conceição;
Lopes-Costa, Pedro Vitor;
Pereira, Renato de Oliveira;
Melo, Mariella de Almeida;
Costa-Silva, Danylo Rafhael;
Borges, Carine Soares;
Viana, Jackeline Lopes;
Santos, Alesse Ribeiro dos;
Facina, Gil;
Silva, Benedito Borges da.
OBJECTIVES: Aromatase inhibitors are the first-choice drugs for the treatment of hormone sensitive breast cancer. However, in addition to the scarcity of studies, there are controversies about their effects on vaginal epithelial cell proliferation in rats, especially those in persistent estrus. METHODS:...
Opioids are the main group of pharmacological agents used during the perioperative period and provide a sedative and analgesic component. The observations of opioid consumption in West Europe indicate that this group of drugs is widely used in chronic noncancer pain therapy. Nearly 20 years ago, the firs...
BACKGROUND It was previously demonstrated that CMC-20, a nitazoxanide and N-methyl-1H-benzimidazole hybrid molecule, had higher in vitro activity against Giardia intestinalis WB strain than metronidazole and albendazole and similar to nitazoxanide. OBJETIVES To evaluate the in vitro activity of CMC-20...
Albendazol/química,
Albendazol/farmacología,
Antiprotozoarios/química,
Antiprotozoarios/farmacología,
Proteínas del Citoesqueleto/efectos de los fármacos,
Técnica del Anticuerpo Fluorescente Indirecta,
Giardia lamblia/efectos de los fármacos,
Pruebas de Sensibilidad Parasitaria,
Tiazoles/química,
Tiazoles/farmacología,
Factores de Tiempo
Abstract In live organisms, there is a balance between the production of reactive oxygen species (ROS) and their neutralization. The increased level of these species leads to a condition called redox imbalance. The aim of this study was to evaluate the protective action of isobenzofuranones in primary cu...
Abstract This study aimed to develop and evaluate fermented milk by Lactobacillus reuteri LR92 with addition of juçara pulp (FMJ) and reuterin production in situ. The fermentation process was analyzed for 24 hours and the storage of FMJ for 30 days at 4 °C. During the fermentation, there was consumpti...
Abstract Rice (Oryza sativa L.) is one of the most important crops in the world, and it is considered the primary source of nutritional layout in developing countries in Asia. The glutathione S-transferases (GSTs) superfamily confers to rice protection against biotic and abiotic stress, and herbicide res...
Abstract The kinetics and equilibrium of experimental data of mercury (II) sorption using three different macrophytes E. crassipes, E. azurea and S. ariculata were analyzed. From the kinetic models used, the model 1, which considers the surface area of constant sorption, presents the coefficient of deter...
Ribeiro, Mariana Martinelli Junqueira;
Silva, Karla Marins Mattos da;
Palavecino, Louise Azulay;
Pinto, Laine Celestino;
Ferreira, Bruno Leal Alves;
Lobão, Adriana Quintella;
Castro, Helena Carla;
Montenegro, Raquel Carvalho;
Barros, Claudia Franca;
Joffily, Ana;
Valverde, Alessandra Leda;
Paiva, Selma Ribeiro de.
Abstract Clusia grandiflora belongs to an important botanical family which is known for its medicinal value, however there are few reports in literature about the species, highlighting the relevance of this study. Anatomical studies with leaves and stems were performed using traditional techniques. In th...
Abstract The α-tomatine is a steroidal glycoalkaloid found in immature tomatoes (Lycopersicon esculentum) that has important biological functions including the inhibition of cancer cell growth and preventing metastasis. This study aimed to evaluate the effects of α-tomatine on cytotoxicity, cel...
Abstract The high prevalence of anxiety disorders associated with pharmacotherapy side effects have motivated the search for new pharmacological agents. Species from Citrus genus, such as Citrus limon (sicilian lemon), have been used in folk medicine as a potential therapy to minimize emotional disorders...
