Abstract Hippocampus is a part of the brain that has a major role in spatial learning and memory which can be affected by herbal extracts. Incense resin (Styrax benzoin) has been used by local communities to improve intelligence. However, there is no scientific evidence of the functions of Styrax benzoin...
Atherosclerosis (AS) is a common vascular disease, which can cause apoptosis of vascular endothelial cells. Notoginsenoside R1 (NGR1) is considered an anti-AS drug. MicroRNAs (miRNAs) are believed to play a vital role in cell apoptosis and angiogenesis. This study aimed to explore the mechanism of NGR1 f...
Apoptosis/efectos de los fármacos,
Western Blotting,
Ensayo de Inmunoadsorción Enzimática,
Ginsenósidos/farmacología,
Células Endoteliales de la Vena Umbilical Humana/efectos de los fármacos,
Células Endoteliales de la Vena Umbilical Humana/metabolismo,
Inmunoprecipitación,
Inflamación/metabolismo,
Lipoproteínas LDL/metabolismo,
MicroARNs/efectos adversos,
MicroARNs/metabolismo,
FN-kappa B/antagonistas & inhibidores,
Estrés Oxidativo/efectos de los fármacos,
Especies Reactivas de Oxígeno,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Transducción de Señal,
Receptor Toll-Like 4/antagonistas & inhibidores,
Activación Transcripcional,
Regulación hacia Arriba
In this study, we aimed to analyze the anti-cancer effects of β-elemene combined with paclitaxel for ovarian cancer. RT-qPCR, MTT assay, western blot, flow cytometry, and immunohistochemistry were used to analyze in vitro and in vivo anti-cancer effects of combined treatment of β-elemene and pa...
Apoptosis/efectos de los fármacos,
Western Blotting,
Línea Celular Tumoral,
Movimiento Celular/efectos de los fármacos,
Proliferación Celular/efectos de los fármacos,
Inmunohistoquímica,
Ratones Endogámicos BALB C,
FN-kappa B/efectos adversos,
FN-kappa B/metabolismo,
Neoplasias Ováricas/tratamiento farmacológico,
Neoplasias Ováricas/metabolismo,
Neoplasias Ováricas/patología,
Paclitaxel/administración & dosificación,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Sesquiterpenos/administración & dosificación,
Transducción de Señal,
Transfección
Seregheti, T M Q;
Pinto, A P R;
Gonçalves, M da C;
Antunes, A dos S;
Almeida, W A da S;
Machado, R S;
Silva, J N;
Ferreira, P M P;
Pessoa, C;
Santos, V M R dos;
Nascimento, A M do.
In this paper, we complement our previous study on the antiproliferative activity of Calea fruticosa (Asteraceae) by isolating the compounds apigenin-4',7-dimethyl ether (1), budlein A (2), quercetin (3), and cichoriin (4) from the plant's aerial parts. The antiproliferative activity of these compounds w...
ABSTRACT This study ivestigated the association between noise and impaired sleep quality in 150 physical education instructors, in bodybuilding gyms. Two questionnaires were applied: evaluation of subjective sleep quality and analysis of explanatory variables. Noise exposure was analyzed. For the data an...
Abstract Objective This study evaluated the clinical effect of violet LED light on in-office bleaching used alone or combined with 37% carbamide peroxide (CP) or 35% hydrogen peroxide (HP). Methodology A total of 100 patients were divided into five groups (n=20): LED, LED/CP, CP, LED/HP and HP. Colorim...
Análisis de Varianza,
Peróxido de Carbamida/administración & dosificación,
Colorimetría,
Terapia Combinada,
Esmalte Dental/efectos de los fármacos,
Esmalte Dental/efectos de la radiación,
Sensibilidad de la Dentina/inducido químicamente,
Peróxido de Hidrógeno/administración & dosificación,
Luz,
Fototerapia/métodos,
Valores de Referencia,
Factores de Riesgo,
Espectrofotometría,
Estadísticas no Paramétricas,
Propiedades de Superficie/efectos de los fármacos,
Propiedades de Superficie/efectos de la radiación,
Blanqueamiento de Dientes/métodos,
Blanqueadores Dentales/administración & dosificación,
Resultado del Tratamiento
Abstract Proanthocyanidin has been shown to be efficient in inhibiting matrix metalloproteinases. Objective The aim of this in situ study was to evaluate the protective effect of Proanthocyanidin-based mouthrinses either with naturally acidic or with a neutral pH applied on dentin subjected to erosion. ...
Abstract Objectives This study evaluated if the use of a bioactive glass-ceramic-based gel, named Biosilicate (BS), before, after or mixed with bleaching gel, could influence the inflammation of the dental pulp tissue of rats' molars undergoing dental bleaching with hydrogen peroxide (H2O2). Methodolo...
Pulpa Dental/efectos de los fármacos,
Pulpa Dental/patología,
Vidrio/química,
Peróxido de Hidrógeno/efectos adversos,
Peróxido de Hidrógeno/química,
Diente Molar,
Pulpitis/inducido químicamente,
Pulpitis/patología,
Pulpitis/prevención & control,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Blanqueamiento de Dientes/efectos adversos,
Blanqueamiento de Dientes/métodos,
Blanqueadores Dentales/efectos adversos,
Blanqueadores Dentales/química,
Resultado del Tratamiento
Abstract The nucleus accumbens shell (NAcSh) plays a role in appetitive and negative motivation with sex differences in responses. NAcSh and its laterality in metabolic and hormonal responses to chronic stress in female rats is evaluated via transient inactivation of this nucleus during stress induction....
Abstract Norepinephrine in the basolateral amygdala (BLA) plays a pivotal role in mediating the effects of stress on memory functions in the hippocampus, however, the functional contribution of β1-adrenergic receptors on the BLA inputs to the CA1 region of hippocampus and memory function are not wel...
