Abstract Objectives: To capture evidence of the efficacy and safety of pharmacological analgesia for uncomplicated acute sickle-cell pain in pediatric patients compared to placebo. Sources of data: Searches for key evidence were performed from March 1 to 31, 2018, for randomized controlled trials of ph...
Abstract Introduction: Postoperative pain in thoracic surgery in adults is usually severe, and to control it there are many analgesic methods that include paravertebral blockade (PVB). Until now, there is no clarity on which is the most effective technique to perform this blockade. Objective: To descri...
Abstract Introduction Posttonsillectomy pain results in significant morbidity to the patients. There is a disagreement in the literature regarding the use of local anesthetics during tonsillectomy. The aim of this placebo-controlled, double-blind study is to evaluate the effect of peritonsillar a...
Cuidados Intraoperatorios,
Tonsilectomía,
Dolor Postoperatorio/tratamiento farmacológico,
Analgésicos/administración & dosificación,
Dimensión del Dolor/métodos,
Estudios Prospectivos,
Método Doble Ciego,
Placebos/administración & dosificación,
Bupivacaína/administración & dosificación,
Lidocaína/administración & dosificación,
Analgesia,
Dolor Postoperatorio/prevención & control,
Pakistán,
Inyecciones Intravenosas,
Complicaciones Posoperatorias,
Analgésicos/uso terapéutico,
Bupivacaína/uso terapéutico,
Lidocaína/uso terapéutico,
Dolor Postoperatorio/diagnóstico
Abstract Introduction and objectives: Magnesium sulphate has been used in anesthesia because it has relevant clinical features such as: analgesia, autonomic response control and muscle relaxation. Using the agent to establish adequate conditions for tracheal intubation remains controversial. The aim of ...
Oliveira-Macêdo, L A R;
Pacheco, A G M;
Lima-Saraiva, S R G;
Silva, J C;
Oliveira-Júnior, R G;
Souza, G R;
Lavor, E M;
Silva, M G;
Ferro, J N S;
Barreto, E;
Oliveira, V R;
Almeida, J R G S.
Abstract Selaginella convoluta (Arn.) Spring is a species popularly known as "jericó", and used in folk medicine as analgesic and anti-inflammatory. This study aimed to investigate in mice the antinociceptive and anti-inflammatory activities of the hexane (Sc-Hex) and chloroform (Sc-CHCl3) fractions (10...
Abstract Objective: The phytohormone abscisic acid (ABA) as a signaling molecule exists in various types of organisms from early multicellular to animal cells and tissues. It has been demonstrated that ABA has an antinociceptive effect in rodents. The present study was designed to assess the possible r...
Ácido Abscísico/farmacología,
Analgésicos/farmacología,
Western Blotting,
Proteínas Quinasas Dependientes de AMP Cíclico/análisis,
Proteínas Quinasas Dependientes de AMP Cíclico/efectos de los fármacos,
Quinasas MAP Reguladas por Señal Extracelular/análisis,
Quinasas MAP Reguladas por Señal Extracelular/efectos de los fármacos,
Péptidos y Proteínas de Señalización Intracelular/farmacología,
Reguladores del Crecimiento de las Plantas/farmacología,
Ratas Wistar,
Valores de Referencia,
Reproducibilidad de los Resultados,
Médula Espinal/efectos de los fármacos,
Médula Espinal/metabolismo,
Factores de Tiempo
La flexibilidad laboral es característica de la producción estacional agroindustrial, cuyo principal problema es aprovechar con intensidad los períodos en los que se incrementa la producción. Pero, ¿cómo la demandante competitividad laboral influye en las estrategias de los trabajadores para increm...
Trabajadores Rurales,
Analgésicos/efectos adversos,
Automedicación,
Bebidas Energéticas/efectos adversos,
16360,
Costas (Litoral),
Deshidratación/complicaciones,
Dolor/tratamiento farmacológico,
Eliminación Renal,
Insuficiencia Renal Crónica/economía,
Mercado de Trabajo,
Vitaminas/administración & dosificación,
Rendimiento Laboral,
Guatemala
Costa, Tereza Karla Vieira Lopes da;
Barros, Mariana Silva;
Braga, Renan Marrinho;
Viana, Jéssika de Oliveira;
Sousa, Frederico Barbosa de;
Scotti, Luciana;
Scotti, Marcus Tullius;
Batista, André Ulisses Dantas;
Almeida, Reinaldo Nóbrega de;
Castro, Ricardo Dias de.
Abstract We aimed to evaluate the orofacial antinociceptive effect of geraniol in mice and its molecular anchorage mechanism. Seven mice per group (probabilistic sample) were treated with geraniol (12.5, 25 and 50 mg/kg, i.p.), morphine (6 mg/kg, i.p.) and vehicle (saline + Tween 80 at 0.2%, i.p.) 30 min...
The essential oil of Laurus nobilis L. was used to test their antinociceptive efficacy. It was applied intraperitoneally (i.p.) to rats subjected to a nociception test (C reflex and spinal wind-up). The results showed that the essential oil applied at higher doses (0.06 mg/Kg) causes a complete aboliti...
