Results: 128

O impacto clínico e imunológico da matriz derivada de esmalte na cicatrização de cirurgias para recobrimento radicular

O objetivo do presente estudo foi avaliar o impacto clínico e imunológico da matriz derivada de esmalte (EMD) na cicatrização periodontal, após a realização de cirurgias de recobrimento radicular. Dezesseis pacientes, com média de idade de 47,7 anos (DP=7,0), foram submetidos à cirurgia de recob...

Kaempferol inhibited VEGF and PGF expression and in vitro angiogenesis of HRECs under diabetic-like environment

Braz. j. med. biol. res; 50 (3), 2017
Diabetic retinopathy (DR) is one of the common and specific microvascular complications of diabetes. This study aimed to investigate the anti-angiogenic effect of kaempferol and explore its underlying molecular mechanisms. The mRNA expression level of vascular endothelial growth factor (VEGF) and placent...

Expression of the c-MET, HGF and VEGF biomarkers in intestinal and diffuse gastric cancer in the Brazilian population: a pilot study for the standardization of the quantitative PCR technique

Appl. cancer res; 37 (), 2017
Background: Gastric carcinoma (GC) is the third leading cause of death among malignant tumors worldwide, causing approximately 900,000 deaths/year. Changes in oncogenes that encode tyrosine kinase receptors play an important role in the pathogenesis of GC. MET gene is a proto-oncogene that encodes a tyro...

Serum concentration of vascular endothelial growth factor and depth of trophoblastic invasion in ampullary ectopic pregnancy

Clinics; 71 (12), 2016
OBJECTIVE: To evaluate the association between the depth of trophoblastic infiltration and serum vascular endothelial growth factorconcentration in patients with an ampullary pregnancy. METHODS: This prospective cross-sectionalstudy involved 34 patients with an ampullary ectopic pregnancy who underwent ...

Potential therapeutic strategies for non - muscle invasive bladder cancer based on association of intravesical immunotherapy with P-MAPA and systemic administration of cisplatin and doxorubicin

Int. braz. j. urol; 42 (5), 2016
ABSTRACT The present study describes the histopathological and molecular effects of P-MAPA (Protein aggregate magnesium-ammonium phospholinoleate-palmitoleate anhydride) intravesical immunotherapy combined with systemic doxorubicin or cisplatin for treatment of non-muscle invasive bladder cancer (NMIBC) ...

Estrogen deficiency in ovariectomized rats: can resistance training re-establish angiogenesis in visceral adipose tissue?

Clinics; 71 (9), 2016
OBJECTIVE: The purpose of this study was to investigate the effects of resistance training on angiogenesis markers of visceral adipose tissue in ovariectomized rats. METHOD: Adult Sprague-Dawley female rats were divided into four groups (n=6 per group): sham-sedentary, ovariectomized sedentary, sham-res...

Effect of intravitreal anti-VEGF on choroidal thickness in patients with diabetic macular edema using spectral domain OCT

Arq. bras. oftalmol; 79 (3), 2016
ABSTRACT Purpose: To evaluate choroidal thickness (CT) using spectral domain optical coherence tomography (SD-OCT) imaging at baseline and 6 months after intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment in patients with diabetic macular edema (DME). Methods: A retrospective ch...

Análisis de impacto presupuestal de ranibizumab comparado con aflibercept, triamcinolona y bevacizumab para tratamiento de pacientes con edema macular secundario a oclusión de la vena central de retina en Colombia
Ranibizumab budget impact analysis compared to aflibercept, triamcinolone and bevacizumab for treatment of patients with macular edema secondary to central retinal vein occlusion in Colombia

Tecnologías evaluadas: Intervención: Ranibizumab; Comparadores: Aflibercept, triamcinolona y bevacizumab. Población: Pacientes con edema macular secundario a oclusión de la vena central de la retina en Colombia. Perspectiva: Tercer pagado - Sistema General de Seguridad Social en Salud (SGSSS). Horizo...

Análisis de impacto presupuestal de ranibizumab, aflibercept y bevacizumab, para tratamiento de pacientes con degeneración macular relacionada a la edad en Colombia
Análise de impacto orçamentário de ranibizumab, aflibercept e bevacizumab para o tratamento de pacientes com degeneração macular relacionada à idade na Colômbia

Tecnologías evaluadas: Intervención: Ranibizumab; Comparadores: Aflibercept y bevacizumab. Población: Pacientes con degeneración macular relacionada a la edad en Colombia. Perspectiva: Tercer pagador, el Sistema General de Seguridad Social en Salud (SGSSS). Horizonte temporal: El horizonte temporal d...