Abstract The effect of hypothermia treatment on white blood cell (WBC), neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR) and platelet-to-lymphocyte ratio (PLR) values as an indicator of inflammation was evaluated in newborns with hypoxic ischemic encephalopathy (HIE). The study wa...
Araújo, Aurigena Antunes de;
Silva, Edna Maria;
Mafra, Cristiane Assunção da Costa Cunha;
Costa, Íris do Céu Clara;
Barbalho, Amanda Lanna Andrade;
Matos, Iolanda Augusta Fernandes de;
Santos, Matheus Araujo dos;
Lopes, Maria Luiza Diniz de Sousa;
Medeiros, Caroline Addison Carvalho Xavier de;
Soares, Luiz Alberto Lira;
Machado, Janaina Carla Barbosa;
Ferreira, Magda Rhayanny Assunção;
Araújo, Raimundo Fernandes de;
Nascimento, Rubens Maribondo do;
Guerra, Gerlane Coelho Bernardo.
Abstract Curcumin, contained at Turmeric (Curcumalonga), can exert many beneficial pleiotropic activities in the gastrointestinal tract. This study evaluated the antioxidant and anti-inflammatory activity of C. longa on 5-fluorouracil (5-FU)-induced oral mucositis (OM) in hamsters. Phytochemical analysi...
SUMMARY: Diabetes and hypertension account for the majority of chronic kidney injury cases that can lead to renal failure. The link between the leukocytes common antigen (CD45) and diabetic kidney disease (DKD) with and without metformin incorporation in an animal model has not been investigated before. ...
Diabetes Mellitus,
Metformina/administración & dosificación,
Metformina/uso terapéutico,
Hipoglucemiantes/administración & dosificación,
Hipoglucemiantes/uso terapéutico,
Lesión Renal Aguda/prevención & control,
Inflamación,
Modelos Animales de Enfermedad,
Biomarcadores,
Estrés Oxidativo/efectos de los fármacos,
Antígenos Comunes de Leucocito,
Riñón/efectos de los fármacos
SUMMARY: The aim of our study was to investigate the effect of inflammation in the placenta on the pro-apoptotic development after severe preeclampsia. Placenta tissue samples of 15 HELLP syndrome and 15 healthy 35-38th week-pregnant women were involved in the study. Tissue samples were taken only from t...
ABSTRACT This study objective to compare the acute effects between one resistance training bout with high versus moderate intensities on inflammatory markers in women with severe obesity. Experimental crossover study, performed with adult women with severe obesity (BMI ≥ 40.0 kg/m²; age ≥ 18...
Objetivo: Avaliar a severidade da periodontite apical (PA) em ratos expostos à fumaça do cigarro, por meio da análise histológica do perfil inflamatório e imunomarcação macrofágica. Material e Métodos: Foram utilizados trinta e dois ratos machos Wistar distribuídos em quatro grupos (n=8): PA (r...
Objetivo: Avaliação histológica da influência da administração sistêmica de solução de Breu-branco, sob o reparo periodontal e pulpar de incisivos de ratos submetidos a reimplante dentário. Material e método: O composto testado foi obtido a partir do fracionamento da resina de P. heptaphyllum ...
Abstract Acrylamide is a neurotoxic compound. Moreover, anakinra is an interleukin-1 (IL-1) receptor antagonist used in rheumatoid arthritis treatment. This study investigated the effect of anakinra on acrylamide-related neuropathy and neuropathic pain. Acrylamide exposure caused a significant decrease ...
Abstract Curcumin is a plant-derived compound with polypharmacological properties that are hampered by its poor solubility, fast degradation, etc. Wound closure complications that follow tooth extraction are numerous, and relatively frequently additional treatment is needed to prevent unwanted process ch...
Abstract The consumption of cosmetics has been increasing every year and is expected to reach $675 billion by 2020 at an estimated growth rate of 6.4% per year. Exposure to skin irritants is the major cause of non-immunological inflammation of the skin. Therefore, the safety evaluation of cosmetic preser...