Abstract: This article describes the chemical composition of Vernonia chalybaea essential oil, and investigates its antimicrobial, antioxidant and hemolytic activities. The evaluation of the antifungal activity was performed by the broth microdilution method using strains of yeasts and dermatophytic fung...
Antifúngicos/farmacología,
Cetoconazol/farmacología,
Antifúngicos/química,
Antioxidantes/farmacología,
beta Carioferinas/farmacología,
Aceites Volátiles/farmacología,
Aceites Volátiles/química,
Hongos/efectos de los fármacos,
Vernonia/química,
Hongos/clasificación,
Ácido Linoleico/farmacología,
Artemia,
Bacterias/efectos de los fármacos,
Antibacterianos/farmacología
Abstract Anticarsia gemmatalis is one of the main pests of the soybean crop, being controlled mainly with agrochemicals. The environmental and health risks, as well as the development of resistance by the pests, has led to the search for alternative control measures, aiming to use more eco-friendly proce...
Abstract Whey, a by-product of dairy industry, is a feedstock widely employed in the production of biodegradable films. However, these films present some limitations when considering the performance of synthetic polymers, especially biological transformation by decomposition. This work aimed to evaluate ...
Abstract Curcumin (CUR) shows potential use for treating cancer. However, CUR has low solubility and reduced bioavailability, which limit its clinical effect. Therefore, the development of nanocarriers can overcome these problems and can ensure the desired pharmacological effect. In addition, it is manda...
Abstract Chronic inflammation is a common indication of several diseases, e.g. asthma, chronic obstructive pulmonary disease (COPD), atherosclerosis, etc. Benzimidazole derivatives are preferable compounds to design new analgesic and anti-inflammatory substances due to their unique biological features. W...
Abstract The bacterial species employ various types of molecular communication systems recognized as quorum sensing for the synchronization of differential gene expression to regulate virulence traits and biofilm formation. A variety of quorum sensing inhibitors; molecules that interfere with quorum sens...
Abstract Sophorolipids are glycolipids that have natural antimicrobial properties and present great potential in the pharmaceutical field. The present study aimed to produce sophorolipids from Candida bombicola using a chicken fat-based medium and evaluate the antimicrobial activity against Gram-negative...
El autor aborda el caso de la cloroquina y la hidroxicloroquina en el contexto de la actual pandemia de COVID-19, a través de dos ejes centrales. Por un lado, el escándalo a nivel editorial y de comunicación de la evidencia, y por otro, el de la toma de decisiones en salud pública. Describe flagrante...
Arritmias Cardíacas/inducido químicamente,
Azitromicina/uso terapéutico,
Bioética,
Cloroquina/efectos adversos,
Cloroquina/uso terapéutico,
Comunicación en Salud,
Comunicación y Divulgación Científica,
Ensayos Clínicos Controlados Aleatorios como Asunto,
Estudios Observacionales como Asunto,
Ética en Investigación,
Hidroxicloroquina/efectos adversos,
Hidroxicloroquina/uso terapéutico,
Infecciones por Coronavirus/tratamiento farmacológico,
Mala Conducta Científica,
Medicina Basada en la Evidencia,
Neuraminidasa/antagonistas & inhibidores,
Pandemias,
Paroxetina/uso terapéutico,
Práctica Clínica Basada en la Evidencia,
Revisión de la Investigación por Pares/ética,
Salud Pública,
Toma de Decisiones Clínicas,
Coronavirus Relacionado al Síndrome Respiratorio Agudo Severo/efectos de los fármacos
Rheumatoid arthritis (RA) is an autoimmune disease of knee joints involving pain and inflammation. Rhoifolin is a plant flavonoid known to have antioxidant and anti-inflammatory properties. This study was taken to identify the effect of rhoifolin on complete Freund's adjuvant (CFA)-induced arthritis in t...
Artritis Experimental/tratamiento farmacológico,
Artritis Experimental/metabolismo,
Artritis Reumatoide/tratamiento farmacológico,
Artritis Reumatoide/metabolismo,
Biomarcadores/sangre,
Citocinas/sangre,
Disacáridos/administración & dosificación,
Flavonoides/administración & dosificación,
Adyuvante de Freund/administración & dosificación,
Glicósidos/administración & dosificación,
Interleucina-1beta/sangre,
Interleucina-6/sangre,
FN-kappa B/efectos de los fármacos,
FN-kappa B/metabolismo,
Estrés Oxidativo/efectos de los fármacos,
Factor de Necrosis Tumoral alfa/sangre
Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors. Ethanol extract of Antrodia cinnamomea (EEA) has been widely studied for its health benefits including anticancer effects. The purpose of this study was to assess the effects of EEA on HNSCC. Cell proliferation, tra...
Antrodia/química,
Apoptosis/efectos de los fármacos,
Productos Biológicos/farmacología,
Western Blotting,
Línea Celular Tumoral,
Proliferación Celular/efectos de los fármacos,
Etanol/aislamiento & purificación,
Etanol/farmacología,
Neoplasias Pulmonares/tratamiento farmacológico,
Neoplasias Pulmonares/patología,
Ratones Endogámicos BALB C,
Carcinoma de Células Escamosas de Cabeza y Cuello/tratamiento farmacológico,
Carcinoma de Células Escamosas de Cabeza y Cuello/patología,
Factores de Tiempo
