ABSTRACT Introduction: Muscle strength is directly related to its cross-sectional area and the volume of its fibers, but there is no absolute linear relationship between hypertrophy and improvement in athletic performance. Under this complex perspective, muscle training strategies have been implemented ...
Resumo Objetivos descrever estratégia de treinamento mediado pela prática supervisionada à beira-leito para enfermeiros na pandemia de COVID-19 e identificar a percepção dos enfermeiros quanto à contribuição do treinamento na aquisição de conhecimentos e habilidades para o atendimento ao pacie...
Abstract Treatment with plant is considered an effective option against increased antibiotic resistance. In this study antibiofilm activity of methanol (CH3OH), chloroform (CHCl3), ethyl acetate (EtOAc) and water (H2O) extracts of Hypericum atomarium Boiss. which is member of Hypericum genus was evaluate...
Mashiba, Kayane Harumi;
Carobeli, Lucimara Rofrigues;
Souza, Maria Vítoria Felipe de;
Meirelles, Lyvia Eloiza de Freitas;
Mari, Natália Lourenço;
César, Gabriel Batista;
Gonçalves, Renato Sonchini;
Caetano, Wilker;
Damke, Edilson;
Silva, Vânia Ramos Sela da;
Damke, Gabrielle Marconi Zago Ferreira;
Consolaro, Marcia Edilaine Lopes.
Abstract Cervical cancer is a leading cause of death among women. The endocervical adenocarcinoma (ECA) represents an aggressive and metastatic type of cancer with no effective treatment options currently available. We evaluated the antitumoral and anti-migratory effects of hypericin (HYP) encapsulated o...
Poloxámero/análogos & derivados,
Adenocarcinoma/patología,
Fotoquimioterapia/clasificación,
Azida Sódica/administración & dosificación,
d0024230,
Células Epiteliales/clasificación,
Células HeLa/clasificación,
d0024600,
Microscopía Fluorescente/métodos,
d0149300,
Neoplasias/patología,
Neoplasias del Cuello Uterino/patología
Abstract Bauhinia forficata Link aqueous extract is usually recommended as a phytomedicine to reduce blood glucose levels and its biological activity has been linked to the presence of phenolic compounds from B. forficata preparations. Several drying processes are used in the production of dry herbal ext...
Abstract Chagas disease is a neglected parasitic disease caused by Trypanosoma cruzi, whose treatment has remained unsatisfactory for over 50 years, given that it is limited to two drugs. Benznidazole (BZN) is an efficient antichagasic drug used as the first choice, although its poor water-solubility, i...
Trypanosoma cruzi/aislamiento & purificación,
Enfermedades Desatendidas/clasificación,
Análisis Espectral/instrumentación,
Difracción de Rayos X/instrumentación,
Enfermedad de Chagas/patología,
Enfermedades Parasitarias/patología,
Esguinces y Distensiones/clasificación,
Espectroscopía Infrarroja por Transformada de Fourier/métodos,
Preparaciones Farmacéuticas/análisis,
d0129950,
Termogravimetría/métodos,
Técnicas In Vitro/métodos
Abstract Pterocarpus santalinoides is used in Nigerian ethnomedicine to treat diabetes mellitus. This study aimed to establish the antidiabetic property of the plant, and isolate and characterize its active principle. Dried and pulverized leaves (500 g) of P. santalinoides were extracted with 1.8 L of 80...
Extractos Vegetales/análisis,
Pterocarpus/efectos adversos,
Hipoglucemiantes/análisis,
Diabetes Mellitus/patología,
Acetatos/farmacología,
Cromatografía en Capa Delgada/métodos,
Espectrometría de Masas/métodos,
Espectroscopía de Resonancia Magnética/métodos,
Flavonoides/farmacología,
d0017860,
d0070040
Abstract The present study investigated the effects of valerian methanolic extract and valerenic acid on the expression of LL-37 gene and protein in A549 and MRC5 line cells. After preparing Valerian seeds, sowing them in March 2020, and harvesting the rhizome in October 2020, the extract was prepared fr...
Valeriana/efectos adversos,
Extractos Vegetales/efectos adversos,
Catelicidinas/efectos adversos,
Genes/genética,
Cromatografía Líquida de Alta Presión/métodos,
ddcs0244440,
Células A549/clasificación,
Hígado/anomalías,
Péptidos Catiónicos Antimicrobianos/agonistas,
d0024700,
Western Blotting/instrumentación
Abstract The form of drug administration affects the success of treatment, since it can influence adherence of the patient to the therapy. The use of orodispersible films has emerged as a way to overcome some drawbacks of conventional methods of drug delivery, especially for patients experiencing difficu...
Abstract Natural products are considered an important source of the therapeutic arsenal currently available. Among these alternatives are the seeds of Ambrosia peruviana (altamisa), whose extract has shown an anti-inflammatory effect. The main objective of this work was to perform a preformulation study ...
