Abstract INTRODUCTION Anopheles stephensi is the main malaria vector in Southeast Asia. Recently, plant-sourced larvicides are attracting great interests. METHODS: The essential oil was extracted from the leaf of Cinnamomum camphora (L.), and a bioassay was conducted to determine the larvicidal effica...
Anopheles/clasificación,
Anopheles/efectos de los fármacos,
Bioensayo,
Cinnamomum camphora/química,
Insecticidas/aislamiento & purificación,
Insecticidas/farmacología,
Larva/efectos de los fármacos,
Dosificación Letal Mediana,
Mosquitos Vectores/clasificación,
Mosquitos Vectores/efectos de los fármacos,
Aceites Volátiles/aislamiento & purificación,
Aceites Volátiles/farmacología
Abstract INTRODUCTION: The aim of this study was to evaluate some virulence factors in Candida albicans isolates from patients with onychomycosis and determine the correlation between these factors and the antifungal resistance profile. METHODS: Seventy species of C. albicans were confirmed using pol...
Antifúngicos/farmacología,
Proteasas de Ácido Aspártico/biosíntesis,
Biopelículas/crecimiento & desarrollo,
Candida albicans/efectos de los fármacos,
Candida albicans/patogenicidad,
Candida albicans/ultraestructura,
Farmacorresistencia Fúngica,
Hemólisis,
Pruebas de Sensibilidad Microbiana,
Microscopía Electrónica de Rastreo,
Uñas/microbiología,
Onicomicosis/microbiología,
Fosfolipasas/biosíntesis,
Reacción en Cadena de la Polimerasa,
Factores de Virulencia
Abstract INTRODUCTION: Nosocomial and community acquired urinary tract infections (UTIs) are one of the most encountered infections in the world. METHODS: This study aimed to determine the antibiotic susceptibility, phylogeny, and virulence genes of 153 Escherichia coli strains isolated from UTIs. An...
Antibacterianos/farmacología,
Escherichia coli/efectos de los fármacos,
Escherichia coli/genética,
Escherichia coli/aislamiento & purificación,
Infecciones por Escherichia coli/microbiología,
Genotipo,
Pruebas de Sensibilidad Microbiana,
Filogenia,
Reacción en Cadena de la Polimerasa,
ARN Ribosómico 16S,
Infecciones Urinarias/microbiología,
Factores de Virulencia/genética
ABSTRACT Chloroquine (CQ) and its analog hydroxychloroquine (HCQ) were recently included in several clinical trials as potential prophylactic and therapeutic options for SARS-COV-2 infection/covid-19. However, drug effectiveness in preventing, treating, or slowing the progression of the disease is still ...
Antimaláricos/efectos adversos,
Antimaláricos/farmacocinética,
Antimaláricos/farmacología,
Betacoronavirus/efectos de los fármacos,
COVID-19,
Cloroquina/efectos adversos,
Cloroquina/farmacocinética,
Cloroquina/farmacología,
Contraindicaciones de los Medicamentos,
Infecciones por Coronavirus/tratamiento farmacológico,
Hidroxicloroquina/efectos adversos,
Hidroxicloroquina/farmacocinética,
Hidroxicloroquina/farmacología,
Pandemias,
Neumonía Viral/tratamiento farmacológico,
Medición de Riesgo,
SARS-CoV-2
Bello, Graziele Lima;
Morais, Franciele Costa Leite;
de Jesus, Sheile Pinheiro;
Wolf, Jonas Michel;
Gehlen, Mirela;
de Almeida, Isabela Neves;
Figueiredo, Lida Jouca de Assis;
Soares, Tainá dos Santos;
Barcellos, Regina Bones;
Dalla Costa, Elis Regina;
de Miranda, Silvana Spíndola;
Rossetti, Maria Lucia Rosa.
BACKGROUND Early diagnosis of tuberculosis (TB) and identification of strains of Mycobacterium tuberculosis resistant to anti-TB drugs are considered the main factors for disease control. OBJECTIVES To standardise a real-time polymerase chain reaction (qPCR) assay technique and apply it to identify mu...
Antituberculosos/farmacología,
ADN Bacteriano/genética,
Farmacorresistencia Bacteriana/genética,
Marcadores Genéticos/genética,
Genotipo,
Isoniazida/farmacología,
Pruebas de Sensibilidad Microbiana,
Mutación/genética,
Mycobacterium tuberculosis/efectos de los fármacos,
Mycobacterium tuberculosis/genética,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Sensibilidad y Especificidad
BACKGROUND The mechanism of resistance to SbIII in Leishmania is complex, multifactorial and involves not only biochemical mechanisms, but also other elements, such as the immune system of the host. OBJECTIVES In this study, putative changes in the immunological profile of human monocytes infected wit...
Antimonio/farmacología,
Antiprotozoarios/farmacología,
Resistencia a Medicamentos,
Citometría de Flujo,
Inmunidad Innata,
Leishmania braziliensis/efectos de los fármacos,
Leishmania braziliensis/inmunología,
Leishmania infantum/efectos de los fármacos,
Leishmania infantum/inmunología,
Monocitos/inmunología,
Monocitos/parasitología,
Óxido Nítrico/biosíntesis,
Fagocitosis/inmunología
Aydın, Emre;
Yıldırım, Yaşar;
Aydin, Fatma Yilmaz;
Bahadir, Mehmet Veysi;
Kaplan, Ibrahim;
Kadiroğlu, Berfin;
Ketani, Muzaffer Aydin;
Yilmaz, Zülfükar;
Kadiroğlu, Ali Kemal;
Yilmaz, Mehmet Emin.
Abstract INTRODUCTION: Sepsis is an important cause of mortality and morbidity, and inflammatory response and oxidative stress play major roles underlying its pathophysiology. Here, we evaluated the effect of intraperitoneal etanercept administration on oxidative stress and inflammation indicators in t...
Antiinflamatorios no Esteroideos/administración & dosificación,
Antiinflamatorios no Esteroideos/farmacología,
Modelos Animales de Enfermedad,
Etanercept/administración & dosificación,
Etanercept/farmacología,
Inflamación/patología,
Inflamación/prevención & control,
Inyecciones Intraperitoneales,
Riñón/efectos de los fármacos,
Estrés Oxidativo/efectos de los fármacos,
Ratas Sprague-Dawley,
Sepsis/sangre,
Sepsis/patología,
Factor de Necrosis Tumoral alfa/sangre
ABSTRACT OBJECTIVE To describe the process of elaboration and validation of the Scale of Perceptions about Alcohol Consumption in Higher Education Students in a Portuguese sample, considering the relationship between alcohol use rates and students' perceptions about the effects of this consumption. ME...
Consumo de Alcohol en la Universidad/psicología,
Análisis Factorial,
Conductas de Riesgo para la Salud/efectos de los fármacos,
Percepción,
Portugal,
Valores de Referencia,
Reproducibilidad de los Resultados,
Factores Sexuales,
Estudiantes/psicología,
Encuestas y Cuestionarios/normas,
Universidades
Abstract INTRODUCTION: The larvicidal potential of Saussurea costus (Falc.) Lipsch. was studied against the early 4th instar larvae of Anopheles stephensi Liston., Aedes aegypti Linn.,and Culex quinquefasciatus Say. because of the emergence of mosquito resistance to conventional synthetic insecticides. ...
Recent evidence suggests that aerobic physical training may attenuate the deleterious effects of cancer risk factors, including smoking. We investigated the effects of cigarette smoke inhalation and aerobic physical training on the expression of steroid receptors and inflammatory and apoptotic proteins i...
