Results: 3723

Chemical composition and in vitro antibacterial activity of essential oils from Murraya paniculata (L. ) Jack (Rutaceae) ripe and unripe fruits against bacterial genera Mycobacterium and Streptococcus

This study aims to investigate chemical composition of essential oils from Murraya paniculata (L.) Jack (Rutaceae) ripe and unripe fruits and determine their in vitro antibacterial activity. Essential oils were extracted by hydrodistillation from Murraya paniculata (L.) Jack ripe and unripe fruits collec...

Polymeric micelles containing resveratrol: development, characterization, cytotoxicity on tumor cells and antimicrobial activity

Antimicrobial and antitumor activities of resveratrol, a compound found mainly in grapes, have already been demonstrated. However, its low bioavailability is a limiting factor for therapeutic application. Polymeric micelles can be an approach to solve this problem since they can encapsulate hydrophobic s...

Agrobacterium rhizogenes-mediated transformation of Hypericum sinaicum L. for the development of hairy roots containing hypericin

Hypericum sinaicum L. is an endangered Egyptian medicinal plant of high importance due to the presence of naphthodianthrones (hypericins), which have photodynamic properties and pharmaceutical potential. We sought to assess H. sinaicum ability to develop hairy roots that could be cultured in contained co...

Is the efflux pump inhibitor Verapamil a potential booster for isoniazid against Mycobacterium tuberculosis?

The membrane-based efflux pump systems are recognized to have an important role in pathogenicity and drug resistance in Mycobacterium tuberculosis by the extrusion of toxic substrates and drugs from the inner bacillus. This study aimed to investigate the in vitro interaction of Verapamil (VP), an efflux ...

Targeting of temozolomide using magnetic nanobeads: an in vitro study

Temozolomide, a chemotherapeutic drug that is often administered for the treatment of brain cancer has severe side effects and a poor aqueous solubility. In order to decrease the detrimental effect of the drug over healthy cells, a novel drug delivery vehicle was developed where the therapeutic drug was ...

El diagnóstico imagenológico en la atención al paciente con infección por SARS-CoV-2
Imaging diagnosis in SARS-CoV-2 patient care

Rev. inf. cient; 99 (6), 2020
Introducción: La pandemia de la COVID-19 ha requerido de una rápida respuesta de la especialidad Imagenología. Objetivo: Ofrecer un referente respecto a la expresión de la COVID-19 en la tomografía computarizada del pulmón y en la radiografía simple de tórax. Método: En el Hospital General Docen...

El diagnóstico imagenológico en la atención al paciente con infección por SARS-CoV-2

Rev. inf. cient; 99 (6), 2020
RESUMEN Introducción: La pandemia de la COVID-19 ha requerido de una rápida respuesta de la especialidad Imagenología. Objetivo: Ofrecer un referente respecto a la expresión de la COVID-19 en la tomografía computarizada del pulmón y en la radiografía simple de tórax. Método: En el Hospital Ge...

Compreensão dos acadêmicos de medicina sobre os princípios de atendimento inicial aos pacientes queimados

Rev. bras. queimaduras; 19 (1), 2020
OBJETIVO: Avaliar a compreensão dos acadêmicos de medicina sobre o atendimento inicial a pacientes queimados, bem como o aprendizado sobre a temática ao longo do curso. MÉTODO: Trata-se de um estudo transversal descritivo realizado em uma instituição de ensino superior de Minas Gerais, por meio da ...

Development, in vitro biocompatibility, and antitumor efficacy of acetic acid-modified Cordyceps sinensis polysaccharide nanoparticle drug delivery system

Docetaxel-loaded acetic acid conjugated Cordyceps sinensis polysaccharide (DTX-AA-CSP) nanoparticles were prepared through dialysis and their release rates in vitro, particle sizes, zeta potentials, drug loading capacities, and encapsulation efficiencies were characterized for the synthesis of AA-modifie...

Acute Strength Exercise Decreases Satiety by Modifying Blood Cytokines Levels in Physically Active Men

Motriz (Online); 26 (4), 2020
Abstract Aim: Exercise elicits adaptations in several physiological systems, such as the gastrointestinal tract. We evaluated the effects of an acute strength exercise (acute-SE) on gastric satiety and its correlation with creatinine kinase (CK), lactate, and plasma cytokine levels in humans. Methods:...