BACKGROUND: Therapeutic high-frequency ultrasound, microcurrent, and a combination of the two have been used as potential interventions in the soft tissue healing process, but little is known about their effect on the immune system. OBJECTIVE: To evaluate the effects of therapeutic high frequency ultr...
ABSTRACT Objective The present study aimed to validate homeostasis model assessment of insulin resistance (HOMA-IR) in relation to the insulin tolerance test (ITT) in a model of insulin-resistance in Wistar rats induced by a 19-week high-fat diet. Materials and methods A total of 30 male Wistar rats ...
Glucemia/análisis,
Peso Corporal,
Dieta Alta en Grasa,
Ayuno,
Prueba de Tolerancia a la Glucosa/métodos,
Homeostasis,
Insulina/sangre,
Resistencia a la Insulina/fisiología,
Ratas Wistar,
Estándares de Referencia,
Reproducibilidad de los Resultados,
Sensibilidad y Especificidad,
Factores de Tiempo
ABSTRACT Objective To evaluate, in rat offspring, bone changes induced by excess maternal thyroxin during pregnancy and lactation, and to assess the reversibility of these changes after weaning. Material and methods Twenty Wistar rats were distributed in two groups, hyperthyroid and control, that wer...
Factores de Edad,
Animales Recién Nacidos/crecimiento & desarrollo,
Huesos/efectos de los fármacos,
Huesos/metabolismo,
Huesos/patología,
Lactancia/efectos de los fármacos,
Intercambio Materno-Fetal,
Ratas Wistar,
Tiroxina/metabolismo,
Tiroxina/farmacología,
Factores de Tiempo,
Destete
ABSTRACT Purpose: The goal of the present study was to establish a protocol for primary culture of lacrimal gland acinar cells (LGACs) and to assess the effect of adding insulin to the culture media. Methods: LGACs were isolated and cultured from lacrimal glands of Wistar male rats. The study outcomes ...
Células Acinares/citología,
Células Acinares/efectos de los fármacos,
Células Acinares/metabolismo,
Carbacol/metabolismo,
Recuento de Células/métodos,
Separación Celular/métodos,
Insulina/metabolismo,
Insulina/farmacología,
Aparato Lagrimal/citología,
Aparato Lagrimal/metabolismo,
Peroxidasa/metabolismo,
Cultivo Primario de Células/normas,
Ratas Wistar
ABSTRACT Introduction: Osteoclasts and osteoblasts are responsible for regulating bone homeostasis during which the trace element zinc has been shown to exert a cumulative effect on bone mass by stimulating osteoblastic bone formation and inhibiting osteoclastic bone resorption. Objective: The aim of ...
ABSTRACT Objective: to evaluate the effect of L-lysine in the bladder and intestinal epithelia in rats submitted to vesicosigmoidostomy. Methods: we divided forty Wistar rats into four groups: group I - control group (Sham); group II - submitted to vesicosigmoidostomy and treated with L-lysine 150mg/k...
ABSTRACT Objective: to evaluate the effectiveness of an collagen-based adhesive associated with fibrinogen and thrombin in experimental liver injuries in rats. Methods: we randomly divided 30 Wistar rats into three groups: A, B and C. All underwent a standard liver traumatic injury. In group A, the le...
ABSTRACT Objective: to know the effect of nicotine on angiogenesis and myofibroblast formation in anastomoses of the small bowel of rats. Methods: we randomly divided 60 Wistar rats into the groups Nicotine (N) and control (C), according to the proposed treatment. Each group was subdivided into three ...
ABSTRACT Dental materials in general are tested in different animal models prior to the clinical use in humans, except for bleaching agents. Objectives To evaluate an experimental rat model for comparative studies of bleaching agents, by investigating the influence of different concentrations and appli...
Recuento de Células,
Pulpa Dental/efectos de los fármacos,
Pulpa Dental/patología,
Cavidad Pulpar,
Fibroblastos/efectos de los fármacos,
Geles,
Peróxido de Hidrógeno/administración & dosificación,
Modelos Animales,
Odontoblastos/efectos de los fármacos,
Ratas Wistar,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Blanqueamiento de Dientes/métodos,
Blanqueadores Dentales/administración & dosificación
ABSTRACT The understanding of bone repair phenomena is a fundamental part of dentistry and maxillofacial surgery. Objective The present study aimed to evaluate the influence of buried magnetic field stimulation on bone repair in rat calvaria after reconstruction with autogenous bone grafts, synthetic p...
Regeneración Ósea/fisiología,
Sustitutos de Huesos/uso terapéutico,
Trasplante Óseo/métodos,
Durapatita/uso terapéutico,
Magnetoterapia/métodos,
Campos Magnéticos,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Cráneo/cirugía,
Factores de Tiempo,
Resultado del Tratamiento