Results: 1561

Antioxidant effect of Legalon(r) SIL in ischemia-reperfusion injury of rat skeletal muscle

Acta cir. bras; 31 (4), 2016
PURPOSE: To evaluated the potential antioxidant agent Legalon (r) SIL (silibinin-C-2',3-bis(hydrogensuccinat)) in the skeletal muscle of rats. METHODS: IRI was achieved via tourniquet application in Wistar-albino rats. Experimental groups were chosen as (i) sham control, (ii) IRI (3+2 h), (iii) IRI a...

Medical ozone treatment ameliorates the acute distal colitis in rat

Acta cir. bras; 31 (4), 2016
PURPOSE: To investigate the effect of medical ozone treatment on the experimental acute distal colitis in rats. METHODS: Eighteen rats were randomly distributed into three equal groups; control, acute distal colitis (ADC) without and with medical ozone treatment. Rats in the control group were taken sal...

The effects of low level laser therapy on Staphylococcus aureus infected third-degree burns in diabetic rats

Acta cir. bras; 31 (4), 2016
PURPOSE: To characterize the effects of low-level laser (LLL) on third-degree burn wounds which were infected with Staphylococcus aureus (S. aureus) in diabetic rats. METHODS: Thirty streptozotocin-induced diabetic rats were divided into two groups: the control and the LLL groups. Third-degree burns w...

Effects of thymoquinone against cisplatin-induced cardiac injury in rats

Acta cir. bras; 31 (4), 2016
PURPOSE: T o investigate the possible protective effect of thymoquinone (TQ) in cisplatin (CP) induced myocardial injury. METHODS: A total of 28 adult male Wistar-Albino rats were randomly and equally divided into four groups as follows: Group 1 (control), Group 2 (CP at 15 mg/kg dose), Group 3 (TQ 40 ...

Sex differences on solid organ histological characteristics after brain death1

Acta cir. bras; 31 (4), 2016
PURPOSE: To investigate gender differences in the evolution of the inflammatory process in rats subjected to brain death (BD). METHODS: Adult Wistar rats were divided into three groups: female; ovariectomized female; and male rats. BD was induced using intracranial balloon inflation and confirmed by ma...

Evaluation of the inflammatory response induced by different materials in the treatment of perianal fistulas: experimental study in rats

The medical literature has no study evaluating the effectiveness of different materials used as setons in the treatment of perianal fistulas; therefore, there is no evidence of availability of a more effective material than others for this purpose. Objective: To evaluate the inflammatory response induce...

Inflamação renal, alterações metabólicas e oxidativas após 6 semanas de dieta de cafeteria em ratos

J. bras. nefrol; 38 (1), 2016
Resumo Introdução: A obesidade é uma doença em que a inflamação está inteiramente envolvida e pode causar insuficiência renal. Objetivo: Avaliar a influência da exposição a curto prazo de uma dieta de cafeteria sobre a inflamação no tecido renal e a formação de produtos de glicação ava...

ADMINISTRATION OF H2 BLOCKERS IN NSAID INDUCED GASTROPATHY IN RATS: effect on histopathological changes in gastric, hepatic and renal tissues

Arq. gastroenterol; 53 (1), 2016
ABSTRACT Background Nonsteroidal anti-inflammatory drugs induces gastric mucosal lesions because of its acidic properties. Ranitidine, an H2 receptor antagonist, has proved beneficial in patients with gastric ulcers. Objective The present study was performed to assess the effect of administering raniti...

Can thiamine pyrophosphate prevent desflurane induced hepatotoxicity in rats?

Acta cir. bras; 31 (3), 2016
ABSTRACT PURPOSE : To investigate the effects of thiamine pyrophosphate (TPP) against desflurane induced hepatotoxicity. METHODS : Thirty experimental animals were divided into groups as healthy (HG), desflurane control (DCG) , TPP and desflurane group (TDG). 20 mg/kg TPP was injected to intraperitonea...

The effect of amifostine on bacterial translocation after radiation induced acute enteritis

Acta cir. bras; 31 (3), 2016
ABSTRACT PURPOSE: To investigate the effects of amifostine on bacterial translocation and overgrowth in colonic flora after acute radiation enteritis in a rat model. METHODS: Thirty-two female Wistar albino rats were divided into four groups: Group-1 (n=8): only normal saline was administered intrape...