Results: 154

Cytotoxicity and bacterial membrane destabilization induced by Annona squamosa L. extracts

An. acad. bras. ciênc; 89 (3,supl), 2017
ABSTRACT This study aimed to further investigate the cytotoxicity against tumor cell lines and several bacterial strains of Annona squamosa and its mode of action. Methanol extracts of A. squamosa leaves (ASL) and seeds (ASS) were used. ASL showed significant antibacterial activity against S. aureus, K. ...

Relación clonal y detección del gen blaKPC en cepas de Klebsiella pneumoniae resistentes a carbapenémicos, en un hospital de Venezuela

Rev. chil. infectol; 33 (5), 2016
In order to study the clonal relationship and blaKPC gene detection in clinical isolates of Klebsiella pneumoniae resistant to carbapenems, we analyzed 22 clinical isolates of K. pneumoniae with resistance to imipenem and/ or meropenem, isolated in the laboratory of bacteriology at the University Hospita...

First report of TEM-104-, SHV-99-, SHV-108-, and SHV-110-producing Klebsiella pneumoniae from Iran

Abstract: INTRODUCTION: Extended-spectrum beta-lactamases (ESBLs) are bacterial enzymes capable of hydrolyzing beta-lactams. The aim of this study was to describe the prevalence of TEM- and SHV-type ESBL-producing Klebsiella pneumoniae strains in Zahedan, Southeast Iran. METHODS: A total of 170 non-rep...

Resistencia a aminoglucósidos y quinolonas en cepas de Klebsiella pneumoniae aisladas en dos unidades de cuidados intensivos del Hospital Universitario de Los Andes Mérida, Venezuela, entre 2007 y 2009

Med. UIS; 29 (2), 2016
Introducción: el incremento en la resistencia a aminoglucósidos y quinolonas es un grave problema para el tratamiento de las infecciones a nivel mundial. Sin duda uno de los factores que ha contribuido a este incremento, es la gran plasticidad que poseen para adquirir genes que le confieren resistencia...

Factores de riesgo asociados a infecciones por bacterias multirresistentes derivadas de la atención en salud en una institución hospitalaria de la ciudad de Medellín 2011-2014

Infectio; 20 (2), 2016
Objetivo: Establecer los factores de riesgo clínicos relacionados con infecciones asociadas a la atención en salud (IAAS) por bacterias multirresistentes (GMR) en una institución clínica de Medellín, entre los años 2011 y 2014. Materiales y métodos: Estudio de casos y controles, retrospectivo, con...

Klebsiella pneumoniae ESBL formando esferoplastos em sedimento urinário a fresco sem coloração

J. bras. nefrol; 38 (2), 2016
Resumo Um homem de 60 anos de idade foi submetido a transplante renal em 2013 devido à insuficiência renal crônica causada por hipertensão. Ele teve episódios recorrentes de infecção do trato urinário e veio para o hospital devido a 4 dias de febre, dor abdominal, ardência para urinar e náusea....

Over expression of AdeABC and AcrAB-TolC efflux systems confers tigecycline resistance in clinical isolates of Acinetobacter baumannii and Klebsiella pneumoniae

Abstract: INTRODUCTION: Due to the wide use of tigecycline in the treatment of severe infections caused by multidrug-resistant (MDR) bacteria, clinical resistance to tigecycline has increased in recent years. Here, we investigated the relationship between tigecycline resistance and the expression of ef...

Secular trends in Klebsiella pneumoniae isolated in a tertiary-care hospital: increasing prevalence and accelerated decline in antimicrobial susceptibility

Abstract: INTRODUCTION Klebsiella pneumoniae has become an increasingly important etiologic agent of nosocomial infections in recent years. This is mainly due to the expression of virulence factors and development of resistance to several antimicrobial drugs. METHODS This retrospective study examines ...

Carbapenem-resistant Klebsiella pneumoniae colonization in pediatric and neonatal intensive care units: risk factors for progression to infection

Braz. j. infect. dis; 20 (2), 2016
Abstract Background Little is known about factors associated with carbapenem-resistant Klebsiella pneumoniae infections in pediatric patients, who are initally colonized with carbapenem-resistant Klebsiella pneumoniae. Materials and methods A retrospective case–control study was conducted involvi...

Experiencia clínica con infecciones causadas por Klebsiella pneumoniae productora de carbapenemasa, en una institución de enseñanza universitaria en Medellín, Colombia

Infectio; 20 (1), 2016
Antecedentes: Las infecciones por Klebsiella pneumoniae productora de carbapenemasa (KPC) son un problema de salud pública mundial. Desde 2008 nuestra institución experimenta casos endémicos de infecciones por KPC posteriores a un brote cuyo caso índice fue un paciente de Israel admitido para traspla...