Introduction Hypospadias is a multifactorial malformation. Among previously described genes, the MAMLD1 has recently been identified in association with the development of hypospadias. So far, there are no studies in Latin America addressing this gene. The aim of this paper is to describe the presence ...
Proteins are macromolecules exhibiting amphiphilic properties, good biocompatibility, biodegradability, high nutritional value, and show strong interactions with several types of active compounds via hydrogen bonding and electrostatic interactions (1). These plant or animal-derived macromolecules differ ...
Intense use of insecticides has resulted in the selection of extreme levels of resistance in insect populations. Therefore understanding the molecular basis of insecticide resistance mechanisms becomes critical. Penetration resistance refers to modifications in the cuticle that will eventually slow down ...
RESUMEN: La periodontitis crónica es una inflamación de los tejidos que rodean y dan soporte a los dientes. Diversos biomarcadores químicos y pro inflamatorios están aumentados durante el transcurso de la enfermedad. El objetivo del estudio fue determinar los distintos niveles salivales de proteínas...
As proteínas de transferência lipídica (LTPs) são pan-alergênios responsáveis pela reatividade cruzada entre frutos, vegetais e polens. A Pru p 3 (LTP presente no pêssego) é reconhecida como marcador de gravidade na alergia alimentar. A romã e a noz são frutos relatados como causas de reações...
ABSTRACT Objective To evaluate the protein quality and iron bioavailability of a fortifying mixture based on pork liver. Methods Determinations of protein efficiency ratio, net protein utilization, true digestibility and hemoglobin regeneration efficiency by depletion and repletion were performed. In t...
A recent study showed that infectivity of Zika virus (ZIKV) Asian genotype was enhanced by an alanine-to-valine amino acid substitution at residue 188 of the NS1 protein, but the precise time and location of origin of this mutation were not formally estimated. Here, we applied a Bayesian coalescent-based...
El amaranto, quinua y tarwi, son alimentos (cereales) de gran valor nutritivo y medicinal, consecuentemente es importante estudiar estas propiedades para el beneficio en la calidad de la alimentación (por su contenido en macronutrientes) como para la prevención de enfermedades. El desayuno como primera...
Abstract: Background: Mitochondriopathies are multisystem diseases affecting the oxidative phosphorylation (OXPHOS) system. Skin fibroblasts are a good model for the study of these diseases. Fibroblasts with a complex IV mitochondriopathy were used to determine the molecular mechanism and the main affe...
Abstract: Introduction: Relapse occurs in approximately 20% of Mexican patients with childhood acute lymphoblastic leukemia (ALL). In this group, chemoresistance may be one of the biggest challenges. An overview of complex cellular processes like drug tolerance can be achieved with proteomic studies. ...
Antineoplásicos Fitogénicos/farmacología,
Leucemia-Linfoma Linfoblástico de Células Precursoras/tratamiento farmacológico,
ProteómicaMétodos,
Vincristina/farmacología,
Adenosina Trifosfato/metabolismo,
Línea Celular Tumoral,
Proliferación Celular/efectos de los fármacos,
Cromatografía Líquida de Alta Presión,
Resistencia a Antineoplásicos,
Regulación Leucémica de la Expresión Génica,
Mitocondrias/metabolismo,
Leucemia-Linfoma Linfoblástico de Células Precursoras/genética,
Proteínas/metabolismo,
Proteoma/metabolismo,
Transducción de Señal/efectos de los fármacos,
Espectrometría de Masa por Ionización de Electrospray
