Results: 131

Transplantation and survival of mouse inner ear progenitor/stem cells in the organ of Corti after cochleostomy of hearing-impaired guinea pigs: preliminary results

Braz. j. med. biol. res; 49 (4), 2016
In mammals, damage to sensory receptor cells (hair cells) of the inner ear results in permanent sensorineural hearing loss. Here, we investigated whether postnatal mouse inner ear progenitor/stem cells (mIESCs) are viable after transplantation into the basal turns of neomycin-injured guinea pig cochleas....

Anti-inflammatory effects of Salvia plebeia R. Br extract in vitro and in ovalbumin-induced mouse model

Biol. Res; 49 (), 2016
BACKGROUND: Asthma is an increasing global health problem, and novel strategies to prevent or ameliorate the condition are needed. Here, the effects of 80 % ethanol extracts of Salvia plebeia R. Br. (SE) on an induced inflammatory response were investigated RESULTS: Salvia plebeia R. Br. inhibited produc...

Morphometric alterations induced by the toxicity of variable sizes of silver nanoparticles

Int. j. morphol; 33 (2), 2015
Silver nanoprticles (SNPs) are invested in medical, industrial and environmental applications. Little if any, is known about the morphometric alterations induced by the toxicity of SNPs. The aim of the present work is to find out the effect of variable size of SNPs on different morphometric parameters. A...

Protective effect of Tribulus terrestris hydroalcoholic extract against cisplatin­induced apoptosis on testis in mice

Int. j. morphol; 33 (1), 2015
Cisplatin is an anti-cancer drug used in chemotherapy. One of the limiting side effects of cisplatin is decreasing genital gland function, azoospermia and oligospermia. Tribulus terrestris (TT) has been used as an aphrodisiac. The present study amid to investigate protective effect of TT hydroalcoholic e...

Protective effect of Tribulus terrestris hydroalcoholic extract against cisplatin-induced cytotoxicity on sperm parameters in male mice

Int. j. morphol; 32 (2), 2014
Cisplatin is an anti-cancer drug used in chemotherapy. One of the limiting side effects of cisplatin is decreasing genital gland function, azoospermia and oligospermia. Tribulus terrestris has been used as an aphrodisiac. The present study amid to investigate protective effect of Tribulus terrestris hydr...

Regulatory B cells present in lymph nodes draining a murine tumor

Medicina (B.Aires); 74 (3), 2014
In cancer, B cells have been classically associated with antibody secretion, antigen presentation and T cell activation. However, a possible role for B lymphocytes in impairing antitumor response and collaborating with tumor growth has been brought into focus. Recent reports have described the capacity o...

Protection effect of sanguinarine on whole-body exposure of X radiation in BALB/c mice

Braz. j. pharm. sci; 50 (1), 2014
To investigate the effects of sanguinarine (SAN) on acute radiation induced injury in mice, 45 mice were randomly divided into control, 10 Gy and SAN+10 Gy groups. Mice in the 10 Gy and SAN+10 Gy groups were exposed to single X-ray radiation with an accumulated dose of 10 Gy. Mice in the SAN+10 Gy group ...

Immune enhancement activities of silk lutein extract from Bombyx mori cocoons

Biol. Res; 47 (), 2014
BACKGROUND: Declining immune function poses an important clinical challenge worldwide and supplementation with natural products that possessing immune enhancing properties is a promising approach for preventing or delaying immune function decline. Cocoons from yellow silkworms are a significant source of...

Immunopathological features developing in the mosquito midgut after feeding on anopheles gambiae mucin-1 / interleukin-12 cDNA immunized mice

Int. j. morphol; 31 (1), 2013
The mosquito midgut is the organ into which the blood meal passes and in which, within a peritrophic membrane secreted by the epithelium, the blood is retained during digestion and absorption. The mosquito midgut is lined with an actin filled microvilli that are exposed to the harsh environment of the gu...

El lipofosfoglicano de Leishmania major modula la expresion de receptores involucrados en la internalización del parasito en celulas de Langerhansde la piel
Leishmania major lipophosphoglycan modulates the expression of receptors involved in parasite internalization in skin Langerhans cells

Acta cient. venez; 53 (3), 2002
Debido a la importancia demostrada de las células de Langerhans (LC) de la piel, que al ser expuestas a antígenos los fagocitan y adquieren la capacidad de presentarlos a los linfocitos T, en el presente trabajo exploramos si el lipofosfoglicano (LPG), el glicolípido más abundante en la superficie de...