ABSTRACT Background A/H1N1 influenza is a viral disease that affects a significant part of the population mainly in winter, leading to increased number of medical consultations, hospitalizations and consequently care spending in emergency. Methods This is a case-series retrospective study, involving pa...
Brasil/epidemiología,
Comorbilidad,
Fiebre/epidemiología,
Hospitales Universitarios/estadística & datos numéricos,
Subtipo H1N1 del Virus de la Influenza A,
Gripe Humana/epidemiología,
Gripe Humana/patología,
Gripe Humana/terapia,
Tiempo de Internación,
Estudios Retrospectivos,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
Factores de Riesgo,
Taquipnea/epidemiología,
Factores de Tiempo
Abstract Purpose: To evaluate the effects of 1,25 dihydroxy vitamin D3 (1,25(OH)2D3) on the content of triglyceride (TG), as well as on the gene and protein expressions of adiponectin receptor 2 (AdipoR2), p38 mitogen-activated protein kinase (P38MAPK), and lipoprotein lipase (LPL) in the liver of rats...
Glucemia/análisis,
Western Blotting,
Peso Corporal,
Calcitriol/farmacología,
Diabetes Mellitus Tipo 2/metabolismo,
Diabetes Mellitus Tipo 2/prevención & control,
Ensayo de Inmunoadsorción Enzimática,
Expresión Génica,
Lipoproteína Lipasa/análisis,
Lipoproteína Lipasa/efectos de los fármacos,
Hígado/efectos de los fármacos,
Hígado/metabolismo,
Ratas Wistar,
Receptores de Adiponectina/análisis,
Receptores de Adiponectina/efectos de los fármacos,
Valores de Referencia,
Reproducibilidad de los Resultados,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
Triglicéridos/sangre,
Regulación hacia Arriba,
Proteínas Quinasas p38 Activadas por Mitógenos/análisis,
Proteínas Quinasas p38 Activadas por Mitógenos/efectos de los fármacos
Abstract INTRODUCTION: Dengue virus (DENV) is the most important arthropod-borne viral disease worldwide with an estimated 50 million infections occurring each year. METHODS: In this study, we present a flow cytometry assay (FACS) for diagnosing DENV, and compare its results with those of the non-str...
Anticuerpos Antivirales/sangre,
Separación Celular,
Cromatografía de Afinidad,
Dengue/diagnóstico,
Virus del Dengue/genética,
Virus del Dengue/inmunología,
Citometría de Flujo,
Fluorescencia,
Leucocitos Mononucleares/virología,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
Sensibilidad y Especificidad,
Proteínas no Estructurales Virales/genética
Background: Although immunosuppressive therapies have made organ transplantation a common medical procedure worldwide, chronic toxicity has a major issue for long-term treatment. One method to improve therapies and methods is the application of immunomodulatory agents from parasites such as Hypoderma lin...
Dípteros/inmunología,
Dípteros/enzimología,
Interferones/antagonistas & inhibidores,
Interleucinas/antagonistas & inhibidores,
Terapia de Inmunosupresión,
Rechazo de Injerto/inmunología,
Rechazo de Injerto/enzimología,
Ensayo de Inmunoadsorción Enzimática,
Rechazo de Injerto/prevención & control,
Serina Endopeptidasas/inmunología,
Serina Endopeptidasas/metabolismo,
Citocinas,
Western Blotting,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Interleucina-10/metabolismo,
Receptor Toll-Like 4
SUMMARY: Toxic effects of anti-cancer and other drugs on the normal tissues could be reduced by the herbal plants and their fractions. This study investigated the protective effect of Tribulus terrestris (TT) on Cisplatin- induced cytotoxicity germ cell apoptosis in male mice. In this experimental study,...
Abstract: IL-22 has been implicated in the pathogenesis of vitiligo. However, the role of aryl hydrocarbon receptor transcription factor that acts as a master regulator of IL-22-producing Th22 cells is not fully understood. The goal of this study was to investigate the expression pattern of aryl hydrocar...
ABSTRACT Saccharum spontaneum has been used for the development of energy cane a crop aimed to be used for the production of second-generation ethanol, or lignocellulosic ethanol. Lignin is a main challenge in the conversion of cell wall sugars into ethanol. In our studies to isolate the genes the lignin...
BACKGROUND The insect chitinase gene family is composed by more than 10 paralogs, which can codify proteins with different domain structures. In Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil, a chitinase cDNA from adult female insects was previously characterized. The predict...
ABSTRACT Dengue fever is a vector-transmitted viral infection. Non-vectorial forms of transmission can occur through organ transplantation. We reviewed medical records of donors and recipients with suspected dengue in the first post-transplant week. We used serologic and molecular analysis to confirm the...
BACKGROUND Aedes aegypti is considered the main Zika virus (ZIKV) vector, and is thought to be responsible for the 2015-2016 outbreak in Brazil. Zika positive Ae. aegypti males collected in the field suggest that vertical and/or venereal transmission of ZIKV may occur. OBJECTIVES In this study, we aime...
