Accidents or diseases can affect the peripheral part of the nervous system, which raises clinical and surgical therapies, among others. In this context, the technique of end-to-side neurorrhaphy is a treatment option, yet its modification loop needs some additional efficacy studies. The purpose of this s...
Nicotine is the most important alkaloid compound in tobacco. One of the major effects of nicotine is stimulation of mesocorticolimbic system. Prefrontal cortex plays a pivotal role in personality and mental state. It is considered the main cause of addiction as it is located in mesocorticolimbic dopamine...
The pharmacological manipulation with selective inhibitor of serotonin reuptake (SSRIs) can modify the operation of the serotonergic system and may facilitate or inhibit the action of this system, inducing changes in the morphology of the skeletal muscle of rats. The objective of this study was to evalua...
The aim of this research was to investigate the effect of testosterone propionate administration in the liver of rats. The rats were divided in the following groups: Initial control (SC), Aged control (SE) and Anabolic group (SA). Testosterone propionate was administered three times per week during 16 we...
We tested the hypothesis that Moringa oleifera impairs the morphology and functions of the kidney in rats. Twenty-four adult male Wistar rats were employed in the study. Rats of Control Group I received physiological saline while rats of Groups II IV received 250, 500 and 750 mg/kg bodyweight of metha...
Moringa oleifera,
Extractos Vegetales/toxicidad,
Riñón/efectos de los fármacos,
Tamaño de los Órganos/efectos de los fármacos,
Alanina Transaminasa/efectos de los fármacos,
Alanina Transaminasa/análisis,
Aspartato Aminotransferasas/efectos de los fármacos,
Aspartato Aminotransferasas/análisis,
Urea/análisis,
Ratas Wistar,
Moringa oleifera,
Extractos Vegetales/toxicidad,
Riñón/efectos de los fármacos,
Tamaño de los Órganos/efectos de los fármacos,
Alanina Transaminasa/efectos de los fármacos,
Alanina Transaminasa/análisis,
Aspartato Aminotransferasas/efectos de los fármacos,
Aspartato Aminotransferasas/análisis,
Urea/análisis,
Ratas Wistar
La encefalopatía por hipoxia es causa de discapacidad y requiere de nuevas estrategias terapéuticas. El pirofosfato de tiamina (PPT) es un cofactor esencial de enzimas fundamentales en el metabolismo de la glucosa, cuya disminución puede conducir a la falla en la síntesis de ATP y a la muerte celular...
Tiamina Pirofosfato/administración & dosificación,
Tiamina Pirofosfato/farmacología,
Apoptosis/efectos de los fármacos,
Hipoxia/tratamiento farmacológico,
Encefalopatías/prevención & control,
Animales Recién Nacidos,
Sustancias Protectoras/administración & dosificación,
Sustancias Protectoras/farmacología,
Análisis de los Gases de la Sangre,
Oxígeno/sangre,
Concentración de Iones de Hidrógeno,
Ratas Wistar,
Modelos Animales de Enfermedad
Dichlorvos (DDVP), an organophosphorus pesticide is a volatile compound which enters the human body through oral, dermal and inhalational routes and is excreted via the kidney. This study assessed the effects of DDVP on the histology of the kidney. Twenty five male rats (75.05 ± 5.55 g) were divided int...
Antioxidantes/administración & dosificación,
Antioxidantes/farmacología,
Vitaminas/administración & dosificación,
Vitaminas/farmacología,
Diclorvos/toxicidad,
Plaguicidas/toxicidad,
Ratas Wistar,
Glomérulos Renales/efectos de los fármacos,
Riñón/efectos de los fármacos,
Suplementos Dietéticos,
Glomérulos Renales/ultraestructura,
Administración por Inhalación
El núcleo supraquiasmático (NSQ) es el principal reloj biológico de los mamíferos y sincroniza la actividad de la glándula pineal al ciclo luz-oscuridad a través de una vía polisináptica. El efecto de asa de retroalimentación neuroendocrina se lleva a cabo por la melatonina. El presente trabajo ...
Previous study has shown the adverse effects of gestational diabetes on hippocampal neuronal density in animal model. This study was conducted to determine the effect of gestational diabetes on rat cerebellum in early postnatal life. In this experimental study, 10 dams randomly allocated into control and...
The rat is probably the most commonly used animal in scientific research. There are many benefits to its use such as: ability to work a large number of animals allowing greater statistical validity, the relatively short life cycles. However, the scant literature regarding the anatomy and morphology of th...
