5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) are modified cytosines found in mammals that are involved in the regulation of gene expression. The aim of this study was to characterize the global patterns of 5-mC and 5-hmC of the fetal placenta of Nellore cattle as well as blood and sperm as...
Abstract INTRODUCTION: Serological cross-reactivity between leishmaniasis and Chagas disease, especially at low titers, leads to difficulties of the seroepidemiological interpretation. METHODS: We have studied the ability of urea as a chaotrope to select high-avidity antibodies in IgG ELISA, thus red...
Anticuerpos Antiprotozoarios/sangre,
Afinidad de Anticuerpos/inmunología,
Biomarcadores/química,
Brasil/epidemiología,
Enfermedad de Chagas/complicaciones,
Enfermedad de Chagas/diagnóstico,
Enfermedad de Chagas/epidemiología,
Enfermedad de Chagas/inmunología,
Ensayo de Inmunoadsorción Enzimática,
Inmunoglobulina G/sangre,
Leishmaniasis/complicaciones,
Leishmaniasis/diagnóstico,
Leishmaniasis/epidemiología,
Leishmaniasis/inmunología,
Vigilancia de la Población,
Sensibilidad y Especificidad,
Urea/química,
Urea/farmacología,
Reacciones Cruzadas/inmunología
Abstract Purpose: To investigate the protective effects of Polygonatum sibiricum polysaccharide (PSP) on acute heart failure (AHF) in rats. Methods: Sixty rats were randomly divided into control, model, and low-, middle- and high-dose PSP groups, 12 rats in each group. The low-, medium- and high-dose...
Enfermedad Aguda,
Apoptosis/efectos de los fármacos,
Modelos Animales de Enfermedad,
Doxorrubicina/farmacología,
Insuficiencia Cardíaca/prevención & control,
Estrés Oxidativo/efectos de los fármacos,
Polygonatum/química,
Polisacáridos/uso terapéutico,
Ratas Sprague-Dawley,
Proteína X Asociada a bcl-2/efectos de los fármacos,
Proteína X Asociada a bcl-2/metabolismo
ABSTRACT Nature has always provided an unlimited source of biologically-active compounds. Since the beginning of mankind, humans have sought resources in fauna and flora to treat eye diseases. However, it was only after the Industrial Revolution that extracts of plants and substances of animal origin cou...
SUMMARY BACKGROUND: To determine the concentration of the Lipid Peroxidation Marker: Malondialdehyde (MDA), and Antioxidant Markers: Superoxide Dismutase (SOD), Glutathione Peroxidase (GPX), Catalase (CAL) in umbilical cord blood and in unstimulated saliva in the first 24 and 48 hours of life in the PTN...
Antioxidantes/análisis,
Antioxidantes/metabolismo,
Biomarcadores/análisis,
Catalasa/análisis,
Estudios Transversales,
Sangre Fetal/química,
Rotura Prematura de Membranas Fetales,
Glutatión Peroxidasa/análisis,
Recien Nacido Prematuro,
Malondialdehído/análisis,
Sepsis Neonatal/diagnóstico,
Sepsis Neonatal/metabolismo,
Factores de Riesgo,
Saliva/química,
Superóxido Dismutasa/análisis
Background: Emergence of antibiotic resistance among pathogenic and food spoilage bacteria such as Staphylococcus aureus, Micrococcus luteus, Streptococcus pyogenes, Streptococcus sanguinis, Streptococcus mutans, Bacillus cereus, and Listeria monocytogenes triggered the search for alternative antimicrobi...
Bacteriocinas/biosíntesis,
Bacteriocinas/aislamiento & purificación,
Bacteriocinas/química,
Ligilactobacillus salivarius/metabolismo,
Antibacterianos/química,
Intestinos/microbiología,
Heces/microbiología,
Estabilidad Proteica,
Pruebas de Sensibilidad Microbiana,
Bacterias/crecimiento & desarrollo,
Concentración de Iones de Hidrógeno,
Farmacorresistencia Microbiana,
Pared Celular,
Percepción de Quorum
ABSTRACT Multiple sclerosis (MS) is a demyelinating, progressive and neurodegenerative disease. A disturbance on the hypothalamic-pituitary-adrenal axis can be observed in patients with MS, showing altered cortisol levels. We aimed to identify basal cortisol levels and verify the relationship with clinic...
Resumo Este estudo objetivou determinar o limiar de redução na espessura do compósito de cor da dentina necessário para resultar em mudanças de cor perceptíveis e aceitáveis em restaurações simuladas. Três sistemas de compósitos (Charisma Diamond, IPS Empress Direct e Filtek Z350 XT) foram ava...
Abstract It evaluated the effect of aging by Low Temperature Degradation (LTD), executed after post- processing surface treatments (polishing, heat treatment and glazing), on the surface characteristics (micromorphology and roughness) and on the structural stability (phase transformation and mechanical b...
Materiales Dentales/química,
Pulido Dental/métodos,
Resistencia Flexional,
Calor,
Ensayo de Materiales,
Microscopía de Fuerza Atómica,
Microscopía Electrónica de Rastreo,
Propiedades de Superficie,
Difracción de Rayos X,
Itrio/química,
Circonio/química
