Oliveira-Macêdo, L A R;
Pacheco, A G M;
Lima-Saraiva, S R G;
Silva, J C;
Oliveira-Júnior, R G;
Souza, G R;
Lavor, E M;
Silva, M G;
Ferro, J N S;
Barreto, E;
Oliveira, V R;
Almeida, J R G S.
Abstract Selaginella convoluta (Arn.) Spring is a species popularly known as "jericó", and used in folk medicine as analgesic and anti-inflammatory. This study aimed to investigate in mice the antinociceptive and anti-inflammatory activities of the hexane (Sc-Hex) and chloroform (Sc-CHCl3) fractions (10...
Introdução: A Punica granatum L. (PG), utilizada como medicamento fitoterápico, apresenta propriedades terapêuticas, anti-inflamatórias e antioxidante. Embora diversos estudos já tenham sido realizados com este fitoterápico, seus possíveis efeitos citotóxicos nos tecidos humanos ainda não são ...
Granada (Fruta),
Medicamento Fitoterápico,
Antiinflamatorios,
Antioxidantes,
Fibroblastos,
Técnicas de Cultivo de Célula,
Mucosa Bucal,
Carcinoma de Células Escamosas,
Plantas Medicinales,
Citotoxicidad Inmunológica,
Neoplasias
Existe una tendencia mundial de incremento en prevalencia de enfermedades no transmisibles, que se caracterizan por un estado pro-inflamatorio crónico. Por lo tanto, es importante estudiar la relación entre alimentos y salud. La palta (Persea americana), sobresale en la industria por su valor nutricion...
Abstract Objective: To determine the total level of flavonoids in brown algae extract Padina sp., Sargassum sp., and Turbinaria sp., which could serve as an analgesic and anti-inflammatory drug. Material and Methods: This is an experimental study with a one-shot case study research design. The study s...
28573,
Preparaciones Farmacéuticas,
Flavonoides,
Espectrofotómetros/métodos,
Algas Marinas,
Antiinflamatorios/uso terapéutico,
Phaeophyceae,
Fitoquímicos,
Indonesia/epidemiología,
Estadísticas no Paramétricas,
Sargassum,
Proyectos de Investigación
Cascabulho, Cynthia M;
Meuser-Batista, Marcelo;
Moura, Kelly Cristina G de;
Pinto, Maria do Carmo;
Duque, Thabata Lopes Alberto;
Demarque, Kelly C;
Guimarães, Ana Carolina Ramos;
Manso, Pedro Paulo de Abreu;
Pelajo-Machado, Marcelo;
Oliveira, Gabriel M;
Castro, Solange L De;
Menna-Barreto, Rubem FS.
BACKGROUND Chagas disease, which is caused by the protozoan Trypanosoma cruzi, is endemic to Latin America and mainly affects low-income populations. Chemotherapy is based on two nitrocompounds, but their reduced efficacy encourages the continuous search for alternative drugs. Our group has characterise...
Enfermedad Aguda,
Antiinflamatorios,
Enfermedad de Chagas/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Electrocardiografía,
Naftoquinonas/química,
Naftoquinonas/uso terapéutico,
Nitroimidazoles/química,
Nitroimidazoles/uso terapéutico,
Parasitemia/tratamiento farmacológico,
Factores de Tiempo,
Tripanocidas/química,
Tripanocidas/uso terapéutico
Abstract Glucosamine is known as anti-inflammatory, antioxidant and as neuroprotective as well as using to treat many of diseases. This work aimed to investigate the remedial effect of glucosamine (20mg/kg b.wt) against the damage induced by a single dose of γ-radiation (8Gy) or aluminium chloride (...
Enfermedades Cardiovasculares/etiología,
Exposición a la Radiación/efectos adversos,
Glucosamina/uso terapéutico,
Encefalopatías/etiología,
Cloruro de Aluminio/efectos adversos,
Encefalopatías/tratamiento farmacológico,
Enfermedades Cardiovasculares/tratamiento farmacológico,
Ratas Wistar,
Encefalopatías/patología,
Enfermedades Cardiovasculares/patología,
Reacción en Cadena de la Polimerasa,
Antiinflamatorios/uso terapéutico,
Modelos Animales de Enfermedad
The objective of this study was to compare the safety and efficacy of 0.2% hyaluronic acid (HA) topical gel and dexamethasone topical ointment in the treatment of recurrent aphthous ulcers (RAU) in children. This retrospective observational study included 104 patients who had more than two episodes of or...
Foschetti, D A;
Braga-Neto, M B;
Bolick, D;
Moore, J;
Alves, LA;
Martins, CS;
Bomfin, LE;
Santos, AAQA;
Leitão, RFC;
Brito, GAC;
Warren, CA.
Clostridium difficile causes intestinal inflammation, which increases adenosine. We compared the expression of adenosine receptors (AR) subtypes A1, A2A, A2B, and A3 in HCT-8, IEC-6 cells, and isolated intestinal epithelial cells, challenged or not with Clostridium difficile toxin A and B (TcdA and TcdB)...
Antiinflamatorios,
Proteínas Bacterianas,
Toxinas Bacterianas,
Clostridioides difficile,
Infecciones por Clostridium,
Modelos Animales de Enfermedad,
Enterotoxinas,
Infecciones,
Interleucina-6,
Receptores Purinérgicos P1/metabolismo,
Regulación hacia Arriba
Ávila, Caroline Nickel;
Trindade, Fernanda Moura Ribeiro;
Penteado, Júlia Oliveira;
Janke, Fernanda;
Schneider, Janaína Pereira;
Uecker, Júlia Neitzel;
Rincón, Joao Alveiro Alvarado;
Barros, Carlos Castilho de;
Andreazza, Robson;
Pieniz, Simone.
Abstract The present study aimed to evaluate the anti-inflammatory potential of a Lycium barbarum (L. barbarum) fruit extract in Wistar rats submitted to a palatable diet presenting systemic inflammation induced by lipopolysaccharides (LPS). Forty-two Wistar female rats (Rattus Novergicus) were used with...