Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the in vitro and in vivo antioxidant potential of the methanolic extracts of Inula glomerata and Salacia kraussii. The plant materials were pulverized and extracted with methan...
Inula/química,
Asteraceae/química,
Salacia/química,
Celastraceae/química,
Antioxidantes/química,
Antioxidantes/farmacología,
Estrés Oxidativo/efectos de los fármacos,
Especies Reactivas de Oxígeno,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Compuestos Fenólicos/análisis,
Flavonoides/análisis,
Fitoquímicos/análisis,
Óxido Nítrico/metabolismo,
Ácidos Sulfónicos/metabolismo,
Benzotiazoles/metabolismo,
Ratas Sprague-Dawley
BACKGROUND: In fish farming, the plant extracts containing antioxidant compounds have been added to the diet for enhancing pathogen resistance. In vitro studies evaluating the antioxidant effect of herbal extracts on fish cell models have focused on ROS production and the respiratory burst mechanism. How...
Salmón,
Salmo salar,
Extractos Vegetales/farmacología,
Sambucus nigra/química,
Estrés Oxidativo,
Leucocitos,
Polifenoles/farmacología,
Antioxidantes,
Acuicultura,
Depuradores de Radicales Libres,
Peroxidación de Lípido,
Resistencia a la Enfermedad,
Especies Reactivas de Oxígeno
SUMMARY OBJECTIVE: Many chronic diseases such as malignancy, cardiovascular diseases, endothelial dysfunction, and autoimmune diseases, which have been shown to be related to vitamin D in various studies; have similar relations with CTRP-9, TNFα, and thiol-disulfide hemostasis. We aimed to contribu...
This study was aimed to explore the comparative efficacy of cinnamon bark extract, cinnamaldehyde and kaempferol against acetaminophen (APAP)-induced oxidative stress. Cinnamon bark extract, cinnamaldehyde and kaempferol were utilized or in-vivo analysis. From the results of in-vitro screening tests, ...
Cinnamomum zeylanicum/química,
Acroleína/análogos & derivados,
Acroleína/química,
Quempferoles/química,
Antioxidantes/administración & dosificación,
Fitoquímicos,
Estrés Oxidativo/efectos de los fármacos,
Acetaminofén/toxicidad,
Modelos Animales de Enfermedad,
Extractos Vegetales/administración & dosificación,
Ratones Endogámicos BALB C,
Hígado/efectos de los fármacos,
Cromatografía Líquida de Alta Presión,
Riñón/efectos de los fármacos,
Hígado/patología,
Riñón/patología
Introdução: Diversos alvos farmacológicos têm sido estudados com o objetivo de minimizar as consequências da infecção causada pelo vírus da COVID-19. A hiperinflamação pulmonar foi associada ao estresse oxidativo embasando a administração de antioxidantes, especialmente N-acetilcisteína, que...
Desde o primeiro caso de COVID-19, ocorrido na China em dezembro de 2019, o espec-
tro da doença tem se mostrado muito amplo, incluindo uma miríade de manifestações
hematológicas. Relatamos aqui o caso de um paciente com diagnóstico confirmado de
COVID-19, o qual apresentou, no sangue periférico, ...
Abstract Due to the ethnopharmacological use of Campsiandra laurifolia (Fabaceae), popularly known as Acapurana, to treat wounds and ulcers, associated with the lack of alternative treatments for intestinal inflammations such as ulcerative colitis (UC), the present work sought to characterize its phytoch...
ABSTRACT Introduction Mutations affecting genes involved in oxidative and signaling pathways may be associated with kidney disease in sickle cell anemia. We determined the allele and genotype frequencies of some polymorphisms in the promoter regions of the Heme Oxygenase-1 (HMOX1) [rs2071746 (A > T) ...
ABSTRACT Background Carica papaya Linn. has high nutraceutical and pharmacological values. The leaves possess antimicrobial, anti-tumor and antioxidant properties. They are used to treat thrombocytopenia during dengue fever and the leaf extract is commercially available as tablets under the name Caripil...
Siqueira, Juliana Silva;
Francisqueti-Ferron, Fabiane Valentini;
Garcia, Jéssica Leite;
Silva, Carol Cristina Vágula de Almeida;
Costa, Mariane Róvero;
Nakandakare-Maia, Erika Tiemi;
Moreto, Fernando;
Ferreira, Ana Lúcia A.;
Minatel, Igor Otávio;
Ferron, Artur Junio Togneri;
Corrêa, Camila Renata.
Abstract Introduction: Obesity, diabetes, and hypertension are common risk factors for chronic kidney disease (CKD). CKD arises due to many pathological insults, including inflammation and oxidative stress, which affect renal function and destroy nephrons. Rice bran (RB) is rich in vitamins and minerals...
