Results: 147

Effect of magnesium ion on human osteoblast activity

Braz. j. med. biol. res; 49 (7), 2016
Magnesium, a promising biodegradable metal, has been reported in several studies to increase bone formation. Although there is some information regarding the concentrations of magnesium ions that affect bone remodeling at a cellular level, little is known about the effect of magnesium ions on cell gap ju...

Efectos in vivo del ranelato de estroncio sobre células progenitoras de médula ósea de ratas diabéticas
In vivo effects of strontium ranelate on bone marrow progenitor cells of diabetic rats

Actual. osteol; 12 (2), 2016
La diabetes mellitus (DM) crónica se asocia con reducción en el contenido mineral óseo (osteopenia y osteoporosis). El objetivo de este trabajo fue evaluar la acción del ranelato de estroncio (RaSr) administrado por vía oral a animales control y diabéticos, sobre el potencial osteogénico de célul...

Medium modification with bone morphogenetic protein 2 addition for odontogenic differentiation

Braz. oral res. (Online); 30 (1), 2016
Abstract The aim of this study was to evaluate whether medium modification improves the odontogenic differentiation of human dental pulp stem cells (DPSC) in vitro and in vivo. DPSC isolated from human impacted third molar teeth were analysed for clusters of differentiation with flow cytometry. Odontogen...

Effect of lectin (ScLL) on fibroblasts stimulated with LPS - an in vitro study

Braz. oral res. (Online); 30 (1), 2016
Abstract: The lectin (ScLL) extracted from the Synadenium carinatum plant has been evaluated as an immunomodulator in diseases such as asthma, neosporosis and leishmaniasis. However, it has not yet been evaluated in the oral cavity. This study evaluated the effect of ScLL on viability, proliferation and ...

Response of a co-culture model of epithelial cells and gingival fibroblasts to zoledronic acid

Braz. oral res. (Online); 30 (1), 2016
Abstract Osteonecrosis of the jaw is an adverse effect of bisphosphonates. While the etiopathogenesis of this condition has been investigated, the interactions and effects of bisphosphonates on oral mucosa cells remain unclear. It is hypothesized that cell culture models, such as co-culture or three-dime...

Cytotoxicity and genotoxicity of calcium silicate-based cements on an osteoblast lineage

Braz. oral res. (Online); 30 (1), 2016
Abstract Several calcium silicate-based biomaterials have been developed in recent years, in addition to Mineral Trioxide Aggregate (MTA). The aim of this study was to evaluate the cytotoxicity, genotoxicity and apoptosis/necrosis in human osteoblast cells (SAOS-2) of pure calcium silicate-based cements ...

Chitosan-collagen biomembrane embedded with calcium-aluminate enhances dentinogenic potential of pulp cells

Braz. oral res. (Online); 30 (1), 2016
Abstract The development of biomaterials capable of driving dental pulp stem cell differentiation into odontoblast-like cells able to secrete reparative dentin is the goal of current conservative dentistry. In the present investigation, a biomembrane (BM) composed of a chitosan/collagen matrix embedded w...

Shenhua Tablet inhibits mesangial cell proliferation in rats with chronic anti-Thy-1 nephritis

Biol. Res; 49 (), 2016
BACKGROUND: In China, mesangial proliferative glomerulonephritis (MsPGN) is one of the most common kidney diseases. In this study, we treated a rat model of chronic anti-Thy-1 MsPGN with Shenhua Tablet and evaluated whether the tablet was able to protect the kidney function. Thirty-six Wistar rats were r...

The anti-cancerous activity of recombinant trichosanthin on prostate cancer cell PC3

Biol. Res; 49 (), 2016
CONTEXT: Trichosanthin produced in the root tube of Trichosanthes kirilowii shows anti-tumor activity on a series of cancer cells including Hela, MCF-7, HL-60. But there is little information about its effect on the carcinogenesis of prostate cancer. OBJECTIVE: This work was designed to study the role of...

Ácido hipocloroso: una nueva alternativa como agente antimicrobiano y para la proliferación celular para uso en odontología

El ácido hipocloroso (HOCl) es un potente antimicrobiano no antibiótico utilizado en medicina clínica para el control de infecciones y reparación de heridas. In vivo el HOCl es sintetizado por células del sistema inmune para el control del agente patógeno durante la fagocitosis y ha sido sintetizad...