Results: 1938

A study of the modification of Y-TZP and resin cement with titanium dioxide nanotubes

Titanium dioxide nanotubes (TiO2) have been applied to enhance the mechanical properties of dental materials. Yttria-stabilized tetragonal zirconia polycrystals (Y-TZP) has been increasingly used in dentistry. Aside from its optimal clinical results, Y-TZP is prone to failures related to insufficient thi...

Efeito do laser de baixa intensidade na atividade biológica de células-tronco da polpa de dentes decíduos humanos

O laser de baixa intensidade (LBI) tem apresentado resultados positivos na proliferação de diversos tipos celulares in vitro. A primeira parte do trabalho avaliou o efeito do LBI na proliferação e viabilidade de células-tronco da polpa de dentes decíduos humanos esfoliados (SHED). As células foram...

Estaniocalcina 2 modula eventos importantes para a tumorigênese oral e é um marcador prognóstico para pacientes com carcinoma de células escamosas oral

O hormônio glicoproteico estaniocalcina 2 (STC2) está envolvido na carcinogênese e progressão de muitos tipos de câncer. No entanto, seu significado clínico e mecanismos moleculares no carcinoma de células escamosas oral (CCEO) foram pouco estudados e permanecem incertos. O presente estudo investi...

Análise da expressão imunoistoquímica de regy e de proteínas envolvidas na regulação da apoptose em carcinomas epidermoides de língua oral

O câncer na cavidade oral é uma das lesões malignas mais frequentes na população mundial. Como o processo de desenvolvimento das neoplasias malignas remete a danos que promovem um desequilíbrio na regulação da divisão e morte celular, nos últimos anos, diversos estudos foram realizados com o in...

Effect of the exercise of walkers performed in public squares with spontaneous or prescribed intensity on post-exercise hypotension

ABSTRACT OBJECTIVE To quantify the intensity adopted by walkers in public squares and check the occurrence and magnitude of post-exercise hypotension in the spontaneously adopted intensity and in a prescribed intensity. METHODS In 98 volunteers (38 of them being hypertensive), walkers in public squar...

Cytokine profile in childhood-onset systemic lupus erythematosus: a cross-sectional and longitudinal study

Braz. j. med. biol. res; 50 (4), 2017
Childhood-onset systemic lupus erythematosus (cSLE) exhibits an aggressive clinical phenotype and severe complications. This could be due to a pro-inflammatory cytokine milieu. Therefore, we determined plasma levels of Th1 (IL-2, IFN-γ, TNF), Th2 (IL-4), Th17 (IL-17A, IL-6), and Treg (IL-10) cytokin...

Upregulation of microRNA 142-3p in the peripheral blood and urinary cells of kidney transplant recipients with post-transplant graft dysfunction

Braz. j. med. biol. res; 50 (4), 2017
We analyzed microRNA (miR)-142-3p expression in leucocytes of the peripheral blood and urinary sediment cell samples obtained from kidney transplant recipients who developed graft dysfunction. Forty-one kidney transplant recipients with kidney graft dysfunction and 8 stable patients were included in the ...

Recombinant 60-kDa heat shock protein from Paracoccidioides brasiliensis: is it a good antigen for serological diagnosis of paracoccidioidomycosis?

Braz. j. med. biol. res; 50 (4), 2017
Paracoccidioides brasiliensis and P. lutzii are fungi that cause paracoccidioidomycosis (PCM), the most prevalent systemic mycosis in South America. For serological diagnosis, although 43-kDa glycoprotein (gp43) is regarded as highly specific for PCM, the occurrence of false negative reactions in sera fr...

Cerebral blood flow and vasoreactivity in aging: an arterial spin labeling study

Braz. j. med. biol. res; 50 (4), 2017
Regional cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) in young and elderly participants were assessed using pulsed arterial spin labeling (ASL) and blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) techniques in combination with inhalation of CO2. Pulsed ASL and ...

Seroprevalence of bactericidal antibodies against serogroup B and C Meningococci in a University Hospital

Braz. j. med. biol. res; 50 (5), 2017
Meningococcus serogroup B (MenB), clonal complex 32 (cc 32), was the Brazilian epidemic strain of meningococcal disease (MD) in the 1990’s. Currently, meningococcus serogroup C (MenC), cc 103, is responsible for most of the cases of the disease in Brazil. The aim of this study was to investigate th...