Introduction: Previous retrospective studies have demonstrated that the concentration of chemokine ligand CXCL13 in cerebrospinal fluid (CSF-CXCL13) is a promising biomarker in the diagnosis of neurosyphilis and, additionally, in the monitoring of therapeutic efficacy. Objective: To describe three cases ...
Acetylcholinesterase (AChE), hydrolyzes acetylcholine to choline and acetate, thereby terminating this neurotransmitter effect at cholinergic synapses. Therefore, AChE inhibition is used for counterbalance the cholinergic deficit in Alzheimer’s disease (AD) patients. In the ...
Inhibidores de la Colinesterasa/farmacología,
Flavonoides/análisis,
Enfermedad de Alzheimer/tratamiento farmacológico,
Marruecos,
Fenoles/análisis,
Peroxidación de Lípido/efectos de los fármacos,
Antioxidantes/farmacología,
Rumex,
Taraxacum,
Hypericum,
Inhibidores de la Colinesterasa/química,
Antioxidantes/química,
Especies Reactivas de Oxígeno
Núñez, Marvin J;
Paz-González, Alma D;
Vásquez-Jiménez, Lenci K;
Castillo, Ulises G;
Moo-Puc, Rosa;
Chan-Bacab, Jesús M;
Aguilera-Arreola, Guadalupe;
Catalán-Gonzalez, Lucero;
Quintana-Gómez, Alexis Uriel;
Castañeda-Sánchez, Jorge Ismael;
Luna-Herrera, Julieta;
Rivera, Gildardo.
Currently, in developing countries, parasitic and bacterial diseases as amebiasis, giardiasis, trichonomiasis, leishmaniasis, trypanosomiasis, tuberculosis, and nocardiasis are a public health problem. The pharmacological treatment for these diseases is not completely effective and c...
Flora,
Extractos Vegetales/farmacología,
Antiparasitarios/farmacología,
Antibacterianos/farmacología,
Parásitos/efectos de los fármacos,
Técnicas In Vitro,
El Salvador,
Bacterias/efectos de los fármacos,
Mycobacterium tuberculosis,
Trypanosoma cruzi/efectos de los fármacos,
Extractos Vegetales/química,
Antiparasitarios/química,
Antibacterianos/química,
Pruebas de Sensibilidad Microbiana,
Flavonoides/análisis,
Monoterpenos/análisis,
Amoeba/efectos de los fármacos,
Cromatografía Líquida de Alta Presión
Plants are a source of multiple antineoplastic treatments. However, the effect of many species used in traditional medicine has yet to be demonstrated. In this work, the taxonomic identification of Agave mapisaga was made and a high-performance liquid chromatography-mass spectromet...
Urtica circularis is an Argentinean species traditionally used to treat inflammation symptoms and oxidative stress-related diseases. Considering the uses in folk medicine, the purpose of this work was to evaluate and compare the anti-inflammatory and antioxidant activities of two different U. ...
Kelussia odoratissima fruits are utilized in Persian traditional medicine as a painkiller and to prevent inflammation-based disorders. Considering the higher content of essential oil in the fruits, the oil’s anti-inflammatory and analgesic activities were investigated via the paw ...
Aceites Volátiles/administración & dosificación,
Extractos Vegetales/administración & dosificación,
Antiinflamatorios/administración & dosificación,
Analgésicos/administración & dosificación,
Ratas Wistar,
Apiaceae/química,
Frutas,
Aceites Volátiles/química,
Cromatografía de Gases y Espectrometría de Masas,
Benzofuranos/líquido cefalorraquídeo,
Sesquiterpenos de Germacrano/análisis
Ibervillea sonorae (S. Watson) Greene, is a plant native to Mexico, where its roots have been used traditionally for treating Diabetes Mellitus. The aim of this work was to establishment of cell cultures of stem explants of I. sonorae and evaluation of the anti-hyperglycemic activity of ...
Extractos Vegetales/administración & dosificación,
Extractos Vegetales/química,
Hipoglucemiantes/química,
México,
Hipoglucemiantes/administración & dosificación,
Hiperglucemia/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Técnicas de Cultivo de Célula,
Ácidos Grasos/análisis,
Ratas Wistar,
Fenoles/análisis,
Flavonoides/análisis,
Cromatografía Líquida de Alta Presión,
Glucemia/efectos de los fármacos
Fractions from the Hexane Extract (HE) of Eugenia uniflora L. leaves were subjected to various chromatographic systems. Germacrone sesquiterpene and bornyl acetate bicyclic ester were characterized by High Performance Liquid Chromatography coupled to Mass Spectrometry (HPLC-MS) w...
The stem bark of Geoffroea decorticans (Gill.ex Hook. etArn.) Burk. was used medicinally to cure several skin affections; however, phytochemical and biological antecedents were not found. Analyses of purified methanolic extract from G. decorticans bark (PFGB), realized by silylation d...
Extractos Vegetales/farmacología,
Antibacterianos/farmacología,
Extractos Vegetales/química,
Medicina Tradicional,
Fenoles/análisis,
Fabaceae/química,
Antibacterianos/química,
Corteza de la Planta,
Staphylococcus aureus/efectos de los fármacos,
Enterococcus faecalis/efectos de los fármacos,
Metanol,
Pruebas de Sensibilidad Microbiana,
Cromatografía Liquida/métodos,
Espectrofotometría/métodos
In this study, we investigated the influence of mixture design on the chemical profile of Eugenia unifloraleaves, evaluating the antioxidant and antimicrobial activities, the toxic and hemolytic potential, with the focus on the improvement of the polyphenol’s extraction for in...
Eugenia/química,
Extractos Vegetales/química,
Hemolíticos,
Fitoquímicos,
Antiinfecciosos/química,
Antiinfecciosos/toxicidad,
Antioxidantes,
Taninos/análisis,
Flavonoides/análisis,
Cromatografía Líquida de Alta Presión,
Espectrofotometría/métodos,
Análisis de Varianza,
Bacterias/efectos de los fármacos,
Hongos/efectos de los fármacos,
Pruebas de Sensibilidad Microbiana,
Extractos Vegetales/farmacología,
Antiinfecciosos/farmacología