Abstract Subthalamic nucleus deep brain stimulation (STN DBS) is an established treatment that improves motor fluctuations, dyskinesia, and tremor in Parkinson's disease (PD). After the surgery, a careful electrode programming strategy and medical management are crucial, because an imbalance between them...
Abstract Background: There are currently no methods to predict the development of levodopa-induced dyskinesia (LID), a frequent complication of Parkinson's disease (PD) treatment. Clinical predictors and single nucleotide polymorphisms (SNP) have been associated to LID in PD. Objective: To investigat...
Objective: Parkinson's disease (PD) is often accompanied by stigma, which could contribute to a worse prognosis. The objective of this study is to identify the variables associated with stigma in PD patients who are candidates for deep brain stimulation (DBS). Methods: We investigated sociodemographic a...
Actividades Cotidianas/psicología,
Estudios Transversales,
Estimulación Encefálica Profunda/métodos,
Persona de Mediana Edad,
Enfermedad de Parkinson/psicología,
Enfermedad de Parkinson/terapia,
Calidad de Vida/psicología,
Índice de Severidad de la Enfermedad,
Estigma Social,
Encuestas y Cuestionarios,
Resultado del Tratamiento
Current pharmacotherapy of Parkinson's disease (PD) is palliative and unable to modify the progression of neurodegeneration. Treatments that can improve patients' quality of life with fewer side effects are needed, but not yet available. Cannabidiol (CBD), the major non-psychotomimetic constituent of can...
ABSTRACT Although fatigue is an expressive symptom of Parkinson's disease (PD), few studies have investigated the association between fatigue, mobility and walking capacity of these patients. Objective: To investigate whether fatigue is an independent factor associated with mobility and the walking capac...
Obis, Javier;
Garcia-Martin, Elena;
Orduna, Elvira;
Vilades, Elisa;
Alarcia, Raquel;
Rodrigo, Maria J;
Pablo, Luis E;
Polo, Vicente;
Larrosa, Jose M;
Satue, Maria.
ABSTRACT Purpose: To assess the reproducibility of retinal and choroidal measurements in the macular and peripapillary areas using swept-source optical coherence tomography in patients with Parkinson's disease. Methods: A total of 63 eyes of 63 patients with idiopathic Parkinson's disease were evaluate...
Coroides/anatomía & histología,
Coroides/diagnóstico por imagen,
Coroides/fisiopatología,
Enfermedades de la Coroides/diagnóstico por imagen,
Enfermedades de la Coroides/etiología,
Enfermedad de Parkinson/complicaciones,
Reproducibilidad de los Resultados,
Retina/anatomía & histología,
Retina/diagnóstico por imagen,
Retina/fisiopatología,
Tomografía de Coherencia Óptica/métodos
A Doença de Parkinson (DP) é uma patologia neurodegenerativa, lentamente progressiva. As alterações posturais típicas da DP, associado à rigidez dos músculos intercostais, comprometem a mobilidade da caixa torácica, repercutindo na diminuição da expansibilidade pulmonar na inspiração e da dep...
Abstract Background: New protocols applied in the rehabilitation of Parkinson's disease enable different action strategies for health professionals, as well as a new range of activities for these individuals. However, no valid samba protocol with activity prescription for this population was found in the...
Actividades Cotidianas,
Brasil,
Terapia por Ejercicio/métodos,
Estudios de Factibilidad,
Musicoterapia/métodos,
Ensayos Clínicos Controlados no Aleatorios como Asunto,
Enfermedad de Parkinson/rehabilitación,
Calidad de Vida,
Factores Socioeconómicos,
Factores de Tiempo,
Resultado del Tratamiento
