Results: 410

The diagnostic benefit of antibodies against ribosomal proteins in systemic lupus erythematosus

Adv Rheumatol; 60 (), 2020
Abstract Background Anti-ribosomal P (anti-Rib-P) antibody is a specific serological marker for systemic lupus erythematosus (SLE) and routinely tested by targeting the common epitope of three ribosomal proteins of P0, P1 and P2. This study aimed to investigate if testing antibodies against individual r...

Serum interleukin-6 level is correlated with the disease activity of systemic lupus erythematosus: a meta-analysis

Clinics; 75 (), 2020
Interleukin-6 (IL-6) plays a crucial role in systemic autoimmunity and pathologic inflammation. Numerous studies have explored serum IL-6 levels in systemic lupus erythematosus (SLE) and their correlation with disease activity. Here, we performed a meta-analysis to quantitatively assess the correlation b...

Circulating exosomal micrornas as biomarkers of systemic lupus erythematosus

Clinics; 75 (), 2020
OBJECTIVES: Many studies indicate that microRNAs (miRNAs) could be potential biomarkers for various diseases. The purpose of this study was to investigate the clinical value of serum exosomal miRNAs in systemic lupus erythematosus (SLE). METHODS: Serum exosomes were isolated from 38 patients with SLE an...

Encefalitis por virus herpes humano tipo 6 en una adolescente con lupus eritematoso sistémico. Primer caso reportado en el ecuador

VozAndes; 31 (2), 2020
Se describe el caso de una paciente de catorce años con Lupus Eritematoso Sistémico (LES) con índice de actividad severo y en tratamiento inmunosupresor. Acudió al servicio de Urgencias Pediátricas del Hospital de Especialidades Carlos Andrade Marín, por presentar fiebre, cefalea, náuseas, alucina...

Cavidades pulmonares en Lupus Eritematoso Sistémico

Las lesiones pulmonares cavitadas en pacientes con Lupus Eritematoso Sistémico (LES) han sido descriptas en asociación con neumonitis por citomegalovirus, o secundarias a infecciones fúngicas. Haciendo una revisión en la literatura, se han descripto 13 casos de pacientes con estas lesiones. Presentam...

Polineuropatía desmielinizante inflamatoria crónica como forma de presentación de lupus eritematoso sistémico

Se describe el caso de una mujer de 35 años que presenta polineuropatía desmielinizante inflamatoria crónica como compromiso neurológico en su diagnóstico inicial de lupus eritematoso sistémico (LES). Si bien el compromiso neurológico es de una prevalencia variable en lupus, la asociación que se ...

The role of high mobility proteins (HMGB1) in systemic lupus erythematosus

Rev. colomb. reumatol; 27 (1), 2020
ABSTRACT Introduction: The high mobility group box 1 proteins (HMGB1) are non-histone nuclear proteins reported to be present at high levels in some autoimmune diseases, such as systemic lupus erythematosus (SLE). Likewise, in contrast to healthy individuals, patients with SLE have a higher prevalence ...

Report of a case of probable overlap between systemic erythematous lupus and polyarteritis nodosa

Rev. colomb. reumatol; 27 (1), 2020
ABSTRACT Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with a wide range of clinical manifestations that may affect any organ. Polyarteritis nodosa (PAN) is defined as necrotizing inflammatory changes in the medium and small vessels, a rare form of systemic necrotizing vasculit...

Oral Hygiene and Dental Caries Status on Systemic Lupus Erythematosus Patients: A Cross-Sectional Study

Abstract Objective: To evaluate the oral hygiene and dental caries status on Systemic Lupus Erythematosus (SLE) patients, also it's with SLE disease activity. Material and Methods: This is a descriptive study with a cross-sectional approach. The study was conducted on 93 SLE patients from 2017 to 2019...

Los reumatólogos en la pandemia COVID-19

Rev. chil. reumatol; 36 (1), 2020
Desde fines del 2019 enfrentamos el brote de una nueva infección por coronavirus llamada COVID-19, que rápidamente se transformó en una pandemia y llegó a nuestro país a principios del 2020. Esto ha traído muchas preguntas y desafíos, específicamente en nuestros pacientes con enfermedades autoinm...