SUMMARY OBJECTIVE: Our study aimed to investigate the diagnostic value of lncRNA H19 for coronary artery disease (CAD) and to explore its possible mechanisms. Methods: A total of 30 CAD patients and 30 healthy individuals, as well as patients with different cardiovascular diseases, were included in thi...
Biomarcadores/sangre,
Estudios de Casos y Controles,
Enfermedad de la Arteria Coronaria/sangre,
Enfermedad de la Arteria Coronaria/diagnóstico,
Ensayo de Inmunoadsorción Enzimática,
Persona de Mediana Edad,
ARN Largo no Codificante/sangre,
Curva ROC,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
Factor de Crecimiento Transformador beta1/sangre,
Regulación hacia Arriba
ABSTRACT Objective: To assess the relationships between serum dehydroepiandrosterone sulfate (DHEA-S) levels and heart rate variability (HRV) among different age groups. Subjects and methods: Forty-five healthy men were divided into 3 groups: young age (YA; 20-39 yrs; n = 15), middle age (MA; 40-59 yrs...
ABSTRACT Objective: The aim of this study was to evaluate the relationship between inflammatory cytokines, placental weight, glycated hemoglobin and adverse perinatal outcomes (APOs) in women with gestational diabetes mellitus (GDM). Subjects and methods: This was a prospective, longitudinal and observ...
Biomarcadores/sangre,
Proteína C-Reactiva/análisis,
Diabetes Gestacional/sangre,
Hemoglobina Glucada/análisis,
Interleucina-6/sangre,
Estudios Longitudinales,
Placenta/patología,
Valor Predictivo de las Pruebas,
Resultado del Embarazo,
Estudios Prospectivos,
Factor de Necrosis Tumoral alfa/sangre
ABSTRACT Objective: In this study, we aimed to evaluate serum irisin and apelin levels in patients with subclinical hypothyroidism (SCH) when they were subclinical hypothyroid and become euthyroid after levothyroxine therapy and association of these adipokines with markers of atherosclerosis such as ser...
Apelina/sangre,
Aterosclerosis/sangre,
Aterosclerosis/diagnóstico,
Aterosclerosis/etiología,
Biomarcadores/sangre,
Grosor Intima-Media Carotídeo,
Estudios de Casos y Controles,
Fibronectinas/sangre,
Enfermedad de Hashimoto/sangre,
Enfermedad de Hashimoto/complicaciones,
Enfermedad de Hashimoto/tratamiento farmacológico,
Hipotiroidismo/sangre,
Hipotiroidismo/complicaciones,
Hipotiroidismo/tratamiento farmacológico,
Estudios Prospectivos,
Pruebas de Función de la Tiroides,
Tiroxina/uso terapéutico
ABSTRACT Purpose: To elucidate the prognostic value of systemic inflammatory response in patients with metastatic renal cell carcinoma (mRCC) who are treated with sunitinib, we evaluated the prognostic role of C-reactive protein (CRP) kinetics. This study also compared prognostic models containing CRP k...
Antineoplásicos/uso terapéutico,
Biomarcadores/sangre,
Proteína C-Reactiva/análisis,
Carcinoma de Células Renales/tratamiento farmacológico,
Carcinoma de Células Renales/metabolismo,
Carcinoma de Células Renales/patología,
Estudios de Cohortes,
Estimación de Kaplan-Meier,
Neoplasias Renales/tratamiento farmacológico,
Neoplasias Renales/metabolismo,
Neoplasias Renales/patología,
Persona de Mediana Edad,
Metástasis de la Neoplasia/tratamiento farmacológico,
Metástasis de la Neoplasia,
Pronóstico,
Estudios Retrospectivos,
Sunitinib/uso terapéutico
ABSTRACT OBJECTIVE Analyze whether inflammatory markers are associated with falls among older adults living in Bambuí. METHODS Study that analyzed baseline data from a Bambuí Cohort Study of Aging, involving 1,250 participants. Data about falls were collected from previous 12 months, classified as ...
Accidentes por Caídas,
Envejecimiento,
Biomarcadores/sangre,
Índice de Masa Corporal,
Brasil,
Quimiocinas/sangre,
Escolaridad,
Interleucinas/sangre,
Persona de Mediana Edad,
Estado Nutricional,
Reacción en Cadena de la Polimerasa,
Estudios Prospectivos,
Factores de Riesgo,
Factor de Necrosis Tumoral alfa/sangre
SUMMARY OBJECTIVE Association between type 2 diabetes mellitus and inflammation is well-established. We aimed to study platelet-to-lymphocyte ratio (PLR), a novel inflammatory index derived from hemogram, in diabetic patients in comparison to those in healthy volunteers. METHODS Medical data of type ...
SUMMARY OBJECTIVE Metabolic syndrome (MS) is a clinical entity that associated with increased risk of type 2 Diabetes Mellitus (DM) and cardiovascular diseases. Serum uric acid levels are correlated MS criteria. We hypothesized whether a uric acid to HDL-cholesterol ratio (UHR) could predict diabetic r...
Biomarcadores/sangre,
Colesterol/sangre,
Diabetes Mellitus Tipo 2/sangre,
Diabetes Mellitus Tipo 2/complicaciones,
Síndrome Metabólico/sangre,
Síndrome Metabólico/complicaciones,
Persona de Mediana Edad,
Valor Predictivo de las Pruebas,
Estudios Retrospectivos,
Sensibilidad y Especificidad,
Ácido Úrico/sangre
Abstract INTRODUCTION: Chagas disease (CD) is an important public health problem in Brazil and worldwide. Aging and obesity are important matters in patients with CD, as is hypovitaminosis D3, which can decrease the quality of life of these patients. Immunomodulation mediated by vitamin D3, especially ...
Abstract INTRODUCTION: The present study investigated the association of the rs2794521 polymorphism in the CRP gene in individuals with chronic hepatitis B and C, correlating it with markers of hepatic inflammation, fibrosis scores, viral load, and plasma protein levels. METHODS: The study analyzed 185...
Biomarcadores/sangre,
Proteína C-Reactiva/análisis,
Proteína C-Reactiva/genética,
Estudios de Casos y Controles,
Estudios Transversales,
Genotipo,
Hepatitis B Crónica/sangre,
Hepatitis B Crónica/genética,
Hepatitis C Crónica/sangre,
Hepatitis C Crónica/genética,
Cirrosis Hepática/sangre,
Cirrosis Hepática/virología,
Índice de Severidad de la Enfermedad,
Carga Viral
