Objetivo. Verificar el efecto protector del extracto acuoso de hojas y tallos de Desmodium molliculum EAM (manayupa), en la toxicidad hepática inducida por el naproxeno en ratas Ratus novergicus variedad Wistar albino, hembras. Materiales y métodos. Estudio experimental. Se utilizaron 36 ratas hembras ...
RESUMEN Objetivo Evaluar el efecto analgésico del extracto etanólico de las hojas de Pereskia lychnidiflora, la prospección de metabolitos secundarios y el análisis toxicológico. Materiales y métodos La actividad analgésica fue evaluada mediante la prueba del ácido acético y la formalina en ...
Analgesia,
Analgésicos/toxicidad,
Analgésicos/uso terapéutico,
Cactaceae,
Fitoterapia,
Extractos Vegetales/toxicidad,
Extractos Vegetales/uso terapéutico,
Hojas de la Planta/química,
Analgésicos/química,
Analgésicos/farmacología,
Etanol,
Fitoquímicos/análisis,
Extractos Vegetales/química,
Extractos Vegetales/farmacología
Background: Taraxacum officinale G.H. Weber ex Wiggers is a wild plant used in folk medicine to treat several diseases owing to bioactive secondary metabolites present in its tissue. The accumulation of such molecules in plant cells can occur as a response against abiotic stress, but these metabolites ar...
Abstract This study aimed to evaluate the in vitro antibacterial activity of the phytochemicals thymol, linalool, and citronellol against Streptococcus mutans, Streptococcus salivarius and Streptococcus oralis. Disk diffusion screening on solid medium and measurement of the diameter of the bacterial grow...
Barth, E F;
Pinto, L S;
Dileli, P;
Biavatti, D C;
Silva, Y L;
Bortolucci, W;
Gazim, Z C;
Takemura, O S;
Romagnolo, M B;
Laverde-Junior, A.
Abstract This work describes the preliminary evaluation of cytotoxic, antimicrobial, molluscicidal, antioxidant and anticholinesterase activities from leaf (LECF) and stem bark alcoholic extracts (BECF) of the species Croton floribundus Spreng. (Euphorbiaceae), popularly known as capixingui or tapixingui...
Antibacterianos/farmacología,
Antiinfecciosos/farmacología,
Antioxidantes/farmacología,
Artemia/efectos de los fármacos,
Biomphalaria/efectos de los fármacos,
Croton/química,
Evaluación Preclínica de Medicamentos,
Pruebas de Sensibilidad Microbiana,
Fitoquímicos/análisis,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Hojas de la Planta/química,
Tallos de la Planta/química
Irrespective of progressive treatments, cancer remains to have the utmost rate of treatment failure due to numerous reasons associated. In recent years, the use of traditional medicine in cancer research has established considerable interest. Natural products represent an amazing source for cancer therap...
Abstract Valeriana L. genus is represented in Venezuela by 16 species, 9 of these are endemic of Venezuelan Andes growing in high mountains at 2 800 masl. In this investigation, four species were analyzed in order to determine the main secondary metabolites and antimicrobial activity of extracts obtained...
Background: Epigenetic modifications are key factors modulating the expression of genes involved in the synthesis of phytochemicals. The knowledge of plant epigenetic and genetic variations can contribute to enhance the production of bioactive compounds. These issues have been little explored thus far in...
Nasturtium/genética,
Nasturtium/química,
Brassicaceae/genética,
Brassicaceae/química,
Compuestos Fenólicos/análisis,
Variación Genética,
Epigenómica,
Fitoquímicos,
Metilación de ADN,
Citosina/metabolismo,
Plantas Comestibles,
Repeticiones de Microsatélite,
Análisis del Polimorfismo de Longitud de Fragmentos Amplificados,
Análisis por Conglomerados
Abstract Aspergillus sp., Fusarium sp., and Ramularia sp. were endophytic fungi isolated from Rumex gmelini Turcz (RGT), all of these three strains could produce some similar bioactive secondary metabolites of their host. However the ability to produce active components degraded significantly after cultu...
Ascomicetos/crecimiento & desarrollo,
Ascomicetos/aislamiento & purificación,
Ascomicetos/metabolismo,
Técnicas de Cocultivo,
Endófitos/crecimiento & desarrollo,
Endófitos/aislamiento & purificación,
Endófitos/metabolismo,
Fitoquímicos/metabolismo,
Rumex/crecimiento & desarrollo,
Rumex/metabolismo,
Rumex/microbiología,
Plantones/crecimiento & desarrollo,
Plantones/metabolismo,
Plantones/microbiología,
Factores de Tiempo
ABSTRACT BACKGROUND: Extracts obtained from plants and fruits provide a relatively safe and practical alternative for the conventional medicine of gastrointestinal diseases. The specie Eugenia mattosii, popularly known in Brazil as "cerejinha", belongs to Myrtaceae family. Species of this family present...
Antiulcerosos/administración & dosificación,
Antiulcerosos/farmacología,
Antioxidantes/análisis,
Antioxidantes/farmacología,
Brasil,
Modelos Animales de Enfermedad,
Etanol,
Eugenia/química,
Frutas/química,
Mucosa Gástrica/efectos de los fármacos,
Indometacina,
Fitoquímicos/farmacología,
Fitoterapia,
Extractos Vegetales/administración & dosificación,
Extractos Vegetales/farmacología,
Sustancias Protectoras/farmacología,
Semillas/química,
Úlcera Gástrica/inducido químicamente,
Úlcera Gástrica/prevención & control
