Results: 410

Comparison of lupus patients with early and late onset nephritis: a study in 71 patients from a single referral center

Adv Rheumatol; 60 (), 2020
Abstract Background: Nephritis occurs frequently in systemic lupus erythematosus (SLE) and may worsen disease morbidity and mortality. Knowing all characteristics of this manifestation helps to a prompt recognition and treatment. Aim: To compare the differences in clinical data, serological profile and...

Comparison of urinary parameters, biomarkers, and outcome of childhood systemic lupus erythematosus early onsetlupus nephritis

Adv Rheumatol; 60 (), 2020
Abstract Background: Urinary parameters, anti-dsDNA antibodies and complement tests were explored in patients with childhood-Systemic Lupus Erythematosus (cSLE) early-onset lupus nephritis (ELN) from a large multicenter cohort study. Methods: Clinical and laboratory features of cSLE cases with kidney i...

Periodontal Tissue Condition on Systemic Lupus Erythematosus Patients: A Clinical Study

Abstract Objective: To evaluate periodontal tissue condition on systemic lupus erythematosus (SLE) patients and its characteristics. Material and Methods: This descriptive and cross-sectional study involved 61 SLE patients. Clinical examination of the oral cavity was performed using periodontal index (...

Relationship between neutrophil-to-lymphocyte ratio and systemic lupus erythematosus: a meta-analysis

Clinics; 75 (), 2020
Systemic lupus erythematosus (SLE) is a chronic systematic autoimmune disease. Current methods of diagnosing SLE or evaluating its activity are complex and expensive. Numerous studies have suggested that neutrophil-to-lymphocyte ratio (NLR) is closely correlated with the presence of SLE and its activity,...

Neuropsychiatric lupus erythematosus: future directions and challenges; a systematic review and survey

Clinics; 75 (), 2020
This study aimed to systematically review neuropsychiatric lupus erythematosus (NPSLE) and establish a simplified diagnostic criterion for NPSLE. Publications from 1994 to 2018 in the database (Wanfang data (http://www.wanfangdata.com.cn/index.html) and China National Knowledge Internet (http://www.cnki....

MALAT1 is involved in type I IFNs-mediated systemic lupus erythematosus by up-regulating OAS2, OAS3, and OASL

Braz. j. med. biol. res; 53 (5), 2020
Systemic lupus erythematosus (SLE) is an autoimmune disease associated with an aberrant activation of immune cells partly due to the dysfunction of cytokines such as type I interferons (IFNs). Long non-coding RNA MALAT1 has been found to play a pathogenic role in SLE; however, the underlying mechanisms a...

Associação entre o lúpus eritematoso sistêmico e as doenças periodontais – revisão de literatura

Periodontia; 30 (3), 2020
O Lúpus Eritematoso Sistêmico (LES) é uma desordem reumática, crônica-inflamatória sistêmica e autoimune, mediada pela forte resposta anticorpo-antígeno, sob diversas formas de manifestação. Sua incidência e prevalência têm crescido mundialmente, sendo assim uma doença que ganhou destaque m...

Lupus eritematoso sistémico en actividad y cociente albúmina/globulina invertido, ¿hallazgo propio de la enfermedad?
Systemic Erythematosus Lupus and Albumin-Globulin Index, a specific finding in lupus flares?

Rev. cuba. reumatol; 22 (supl.1), 2020
Introducción: El lupus eritematoso sistémico es el modelo clásico de enfermedad autoinmune. En el desarrollo de la enfermedad intervienen varios tipos de inmunoglobulinas, con predominio de la IgG, IgM e IgA. Objetivo: Describir la utilidad del cociente albúmina/globulina como un indicador de activi...

Sangrado digestivo alto como complicación en un paciente lúpico con síndrome de Eisenmenger
High digestive bleeding as a complication in a lupus patient with Eisenmenger syndrome

Rev. cuba. reumatol; 22 (supl.1), 2020
El síndrome de Eisenmenger es un trastorno multisistémico caracterizado por hipertensión pulmonar con inversión o bidireccionalidad del flujo a través de una comunicación intracardiaca o aortopulmonar. El propósito de este estudio es dar a conocer las características generales del síndrome de Ei...

Endocarditis de Libman-Sacks de válvulas nativas derechas en contexto de síndrome antifosfolípido y lupus eritematoso sistémico: ¡cuando el tratamiento marca la diferencia!

Rev. chil. anest; 49 (4), 2020
We report the case of a 54 years old woman with antiphospholipid syndrome in irregular therapy, admitted due to exertional dyspnea and orthopnea. The transthoracic echocardiogram showed dilated cardiomyopathy with biventricular systolic dysfunction, pulmonary hypertension and masses related to the pulmon...