Results: 277

Esclerosis tuberosa, diagnóstico fetal y materno
Tuberous sclerosis, fetal and maternal diagnosis

La esclerosis tuberosa (ET) es una enfermedad genética, autosómica dominante que tiene expresividad variable y que se caracteriza por la presencia de hamartomas en múltiples órganos de diferentes sistemas (piel, cerebro y corazón). Es causada por mutaciones en los genes TSC1 locus 9q34 y TSC2 locus ...

The impact of interleukin-13 receptor expressions in cell migration of astrocytomas

INTRODUCTION: Astrocytomas are common brain tumors. Increased expression levels of Interleukin-13 Receptor α2 (IL-13RA2) have been reported in astrocytomas. The Interleukin-13 signaling pathway may be associated with cell migration when binding to Interleukin-13 Receptor α1. OBJECTIVE: To inves...

Atypical Teratoid Rhabdoid Tumor in a Child: Case Report

Arq. bras. neurocir; 34 (3), 2015
Atypical teratoid/rhabdoid tumor (ATRT) is a rare and aggressive type of embryonal tumor of the central nervous system (CNS) occurring in childhood. The present study aims to describe the case of a 16-year-old girl who presented with an occipital mass lesion that was diagnosed as ATRT.We present a brief ...

Fundamentals of Brain Tumor Surgery in Eloquent Areas

Arq. bras. neurocir; 34 (2), 2015
Central nervous system tumors are a major cause of morbidity and mortality. Themain pathology involved is brainmetastases, followed by intrinsic gliomas. In nearly all cases, surgery is the initial and most important measure to change natural course of disease. In brain metastases and meningiomas, gross ...

Chondroma of the Cerebral Falx: Case Report of a Very Rare Intracranial Tumor

Arq. bras. neurocir; 34 (2), 2015
Chondromas are a benign cartilaginous tumor that account for approximately 0.5% of primary intracranial tumors. They usually arise from the synchondrosis of the skull base, being rarely reported elsewhere (dura convexity, falx, or even intraparenchymal). Because they are very rare tumors sharing clinical...

Angiolipoma intracraniano adjacente a aneurisma sacular cerebral: relato de caso e revisão da literatura

Arq. bras. neurocir; 34 (2), 2015
Angiolipomas são neoplasias benignas compostas por adipócitos maduros e proliferação vascular angiomatosa de rara ocorrência no Sistema Nervoso Central. É relatado o caso de angiolipoma em cisterna silviana adjacente a aneurisma sacular de artéria cerebral média. São discutidas as característic...

A resistência das células T98G e U87MG à temozolamida está correlacionada com a expressão de genes de reparo de DNA

Os gliomas são tumores cerebrais definidos patologicamente pela presença de células com características histológicas e imuno-histoquímicas que evidenciam diferenciação glial. Dentre eles, os astrocitomas são os mais frequentes em adultos. Estes tumores normalmente apresentam infiltração difusa...

Suppression of miR-221 inhibits glioma cells proliferation and invasion via targeting SEMA3B

Biol. Res; 48 (), 2015
BACKGROUND: Gliomas are the most common primary tumors in the central nervous system. Due to complicated signaling pathways involved in glioma progression, effective targets for treatment and biomarkers for prognosis prediction are still scant. RESULTS: In this study we revealed that a new microRNA (miR)...