ABSTRACT Introduction: The indiscriminate use of androgenic steroids may have deleterious effects on human tissue. Objectives: Evaluate the effects of chronic administration of the steroid nandrolone decanoate (DECA) on autonomic cardiovascular modulation, kidney morphometry and the association between...
Nandrolona Decanoato/efectos adversos,
Sistema Nervioso Autónomo/efectos de los fármacos,
Natación,
Presión Arterial/efectos de los fármacos,
Enfermedades Renales/inducido químicamente,
Sistema Cardiovascular/efectos de los fármacos,
Ratas Wistar,
Modelos Animales de Enfermedad,
Anabolizantes/efectos adversos,
Condicionamiento Físico Animal,
Enfermedades Renales/prevención & control
Vieira-Souza, Lúcio Marques;
Aidar, Felipe J;
Matos, Dihogo Gama de;
Silva, Albená Nunes da;
Miguel-dos-Santos, Rodrigo;
Santos, Jymmys Lopes dos;
Costa, Rôas de Araújo;
Marçal, Anderson Carlos;
Lauton-Santos, Sandra;
Cabral, Breno Guilherme de Araújo Tinôco;
Estevam, Charles dos Santos;
Araújo, Silvan Silva de.
ABSTRACT Introduction: High intensity interval training (HIIT) is a method that is widely used today. Objective: The present study aimed to evaluate the effects of HIIT on markers of oxidative stress and muscle damage in rats. Methods: The sample consisted of 60-day-old Wistar rats, divided into two g...
Introducción: La citología vaginal directa es un método muy utilizado para la evaluación del ciclo estral de las ratas de laboratorio, pero la información acerca de los procedimientos e interpretación de los resultados aparece disgregada en la literatura, lo cual dificulta su empleo en los estudios...
Abstract | Introduction: Strongyloides venezuelensis is a nematode whose natural host is rats. It is used as a model for the investigation of human strongyloidiasis caused by S. stercoralis. The latter is a neglected tropical disease in Ecuador where there are no specific plans to mitigate this parasitic...
Souza, Lidiane M;
Okoshi, Marina P;
Gomes, Mariana J;
Gatto, Mariana;
Rodrigues, Eder A;
Pontes, Thierres H. D;
Damatto, Felipe C;
Oliveira, Leiliane R. S;
Borim, Patrícia Aparecida;
Lima, Aline R. R;
Zornoff, Leonardo A. M;
Okoshi, Katashi;
Pagan, Luana U.
Resumo Fundamento: O exercício físico tem sido considerado uma importante terapia não farmacológica para a prevenção e tratamento das doenças cardiovasculares. No entanto, seus efeitos na remodelação cardíaca leve não são claros. Objetivo: Avaliar a influência do exercício aeróbico sobre...
SUMMARY: Renal ischemia-reperfusion injury (IRI)is an unavoidable consequence in renal transplantation and multiple clinical settings. A debate has been raised about the particular role of hypoxia-inducible factor (HF-1α) in the renal injury pathogenesis and the renal cortex ultrastructural alterati...
SUMMARY: Diabetes mellitus can lead to structural disorders in the brain. One of the most common complications of diabetes, diabetic neuropathy is associated with central nervous system disorders. Aloe vera has anti-diabetic, antioxidant, and neuroprotective effects. This study was designed to evaluate t...
Diabetes Mellitus Experimental/tratamiento farmacológico,
Aloe/química,
Extractos Vegetales/administración & dosificación,
Extractos Vegetales/farmacología,
Hipocampo/efectos de los fármacos,
Factor de Crecimiento Nervioso/efectos de los fármacos,
Administración Oral,
Proteínas Tirosina Quinasas Receptoras/efectos de los fármacos,
Proteínas Tirosina Quinasas Receptoras/genética,
Factor de Crecimiento Nervioso/genética,
Receptor de Factor de Crecimiento Nervioso/efectos de los fármacos,
Receptor de Factor de Crecimiento Nervioso/genética,
Ratas Wistar,
Reacción en Cadena en Tiempo Real de la Polimerasa
Abstract Background High dietary sodium intake can induce endothelial stiffness even without changes in blood pressure. Objectives To evaluate the effects of exercise training and chronic intake of sodium chloride solution on aortic morphology of male offspring of rat dams who consumed flaxseed during ...
SUMMARY: The aim of this study was to determine the relationship of autophagy-enhancing rapamycin (RAPA) and autophagy- inhibitor 3-methyladenine (3-MA) with Nitric oxide synthases (NOS) in Cisplatin (CIS)-induced neurotoxicity in rats. Rats were divided into 4 groups (n=10): Control was applied saline, ...
Síndromes de Neurotoxicidad,
Sirolimus/farmacología,
Adenina/análogos & derivados,
Adenina/farmacología,
Óxido Nítrico Sintasa/efectos de los fármacos,
Cisplatino/toxicidad,
Antineoplásicos/toxicidad,
Ratas Wistar,
Inmunohistoquímica,
Superóxido Dismutasa,
Catalasa,
Malondialdehído,
Interleucina-6,
Ensayo de Inmunoadsorción Enzimática
SUMMARY: The aim of this study is to determine the potential therapeutic effects of CAPE in CP-induced nephrotoxicity in rats. Cisplatin (CP) is an antineoplastic chemotherapeutic used for treatment of many cancer types but its applications may induce nephrotoxicity. Caffeic acid phenethyl ester (CAPE) i...
Riñón/efectos de los fármacos,
Alcohol Feniletílico/análogos & derivados,
Alcohol Feniletílico/farmacología,
Ácidos Cafeicos/farmacología,
Cisplatino/toxicidad,
Antineoplásicos/toxicidad,
Estrés Oxidativo/efectos de los fármacos,
Inflamación,
Ratas Wistar,
Inmunohistoquímica,
Ensayo de Inmunoadsorción Enzimática
