Results: 3070

The effect of periodontal therapy on neopterin and vascular cell adhesion molecule-1 levels in chronic periodontitis patients with and without acute myocardial infarction: a case-control study

J. appl. oral sci; 26 (), 2018
Abstract The presence of neopterin in gingival crevicular fluid (GCF) is a marker for local and acute immune activation, and the presence of vascular cell adhesion molecule (VCAM-1) in GCF is accepted as a marker for chronic vascular inflammation. Objectives This study aimed to evaluate effects of perio...

Structural and mechanical properties of a giomer-based bulk fill restorative in different curing conditions

J. appl. oral sci; 26 (), 2018
ABSTRACT Objective: The main goal of this study was to compare the polymerization degree of bulk-fill giomer resin cured with three different light-curing units (LCUs): a polywave third-generation (Valo); a monowave (DemiUltra: DU); and a second-generation LED (Optima 10: Opt) LCUs by using structural a...

A disponibilização de fósforo nas águas pelo uso de detergentes em pó: aspectos ambientais e de Saúde Pública

Resumo Este artigo aborda a interface social e ambiental da presença de fósforo nas águas de abastecimento, dimensionando os impactos ocasionados pelo uso de detergentes fosfatados em pó sobre a qualidade e a disponibilidade dos recursos hídricos, no tocante à ocorrência da eutrofização. Com bas...

Insulin-loaded polymeric mucoadhesive nanoparticles: development, characterization and cytotoxicity evaluation

Abstract Mucoadhesive nanoparticles are particularly interesting for delivery through nasal or pulmonary routes, as an approach to overcome the mucociliary clearance. Moreover, these nanoparticles are attractive for peptide and protein delivery, particularly for insulin to treat diabetes, as an alternati...

Chemistry Inspired by the Colors of Fruits, Flowers and Wine

An. acad. bras. ciênc; 90 (1,supl.1), 2018
ABSTRACT An overview is provided of the status of research at the frontiers of investigation of the chemistry and photochemistry of two classes of natural plant pigments, the anthocyanins and the betalains, as well as of the pyranoanthocyanin pigments formed from anthocyanins during the maturation of red...

From Medicinal Chemistry to Human Health: Current Approaches to Drug Discovery for Cancer and Neglected Tropical Diseases

An. acad. bras. ciênc; 90 (1,supl.1), 2018
ABSTRACT Scientific and technological breakthroughs have compelled the current players in drug discovery to increasingly incorporate knowledge-based approaches. This evolving paradigm, which has its roots attached to the recent advances in medicinal chemistry, molecular and structural biology, has unprec...

The long and successful journey of electrochemically active amino acids. From fundamental adsorption studies to potential surface engineering tools

An. acad. bras. ciênc; 90 (1,supl.1), 2018
ABSTRACT Proteins have been the subject of electrochemical studies. It is possible to apply electrochemical techniques to obtain information about their structure due to the presence of five electroactive amino acids that can be oriented to the outside of the peptidic chain. These amino acids are L-Trypt...

Brazilian Bioluminescent Beetles: Reflections on Catching Glimpses of Light in the Atlantic Forest and Cerrado

An. acad. bras. ciênc; 90 (1,supl.1), 2018
ABSTRACT Bioluminescence - visible and cold light emission by living organisms - is a worldwide phenomenon, reported in terrestrial and marine environments since ancient times. Light emission from microorganisms, fungi, plants and animals may have arisen as an evolutionary response against oxygen toxicit...

Enzymatic reactions involving the heteroatoms from organic substrates

An. acad. bras. ciênc; 90 (1,supl.1), 2018
ABSTRACT Several enzymatic reactions of heteroatom-containing compounds have been explored as unnatural substrates. Considerable advances related to the search for efficient enzymatic systems able to support a broader substrate scope with high catalytic performance are described in the literature. These ...

Advances in enzyme bioelectrochemistry

An. acad. bras. ciênc; 90 (1,supl.1), 2018
ABSTRACT Bioelectrochemistry can be defined as a branch of Chemical Science concerned with electron-proton transfer and transport involving biomolecules, as well as electrode reactions of redox enzymes. The bioelectrochemical reactions and system have direct impact in biotechnological development, in med...