ABSTRACT Positron emission tomography (PET) is a non-invasive nuclear imaging technique that uses radiotracers to track cell activity. The radiopharmaceutical 18F-fluoro-2-deoxyglucose ([18F] FDG) is most commonly used in nuclear medicine for the diagnosis of various diseases, including stroke. A stroke ...
Abstract Bauhinia forficata Link aqueous extract is usually recommended as a phytomedicine to reduce blood glucose levels and its biological activity has been linked to the presence of phenolic compounds from B. forficata preparations. Several drying processes are used in the production of dry herbal ext...
Abstract Chagas disease is a neglected parasitic disease caused by Trypanosoma cruzi, whose treatment has remained unsatisfactory for over 50 years, given that it is limited to two drugs. Benznidazole (BZN) is an efficient antichagasic drug used as the first choice, although its poor water-solubility, i...
Trypanosoma cruzi/aislamiento & purificación,
Enfermedades Desatendidas/clasificación,
Análisis Espectral/instrumentación,
Difracción de Rayos X/instrumentación,
Enfermedad de Chagas/patología,
Enfermedades Parasitarias/patología,
Esguinces y Distensiones/clasificación,
Espectroscopía Infrarroja por Transformada de Fourier/métodos,
Preparaciones Farmacéuticas/análisis,
d0129950,
Termogravimetría/métodos,
Técnicas In Vitro/métodos
Abstract The present study investigated the effects of valerian methanolic extract and valerenic acid on the expression of LL-37 gene and protein in A549 and MRC5 line cells. After preparing Valerian seeds, sowing them in March 2020, and harvesting the rhizome in October 2020, the extract was prepared fr...
Valeriana/efectos adversos,
Extractos Vegetales/efectos adversos,
Catelicidinas/efectos adversos,
Genes/genética,
Cromatografía Líquida de Alta Presión/métodos,
ddcs0244440,
Células A549/clasificación,
Hígado/anomalías,
Péptidos Catiónicos Antimicrobianos/agonistas,
d0024700,
Western Blotting/instrumentación
ABSTRACT Herein, we examined the protective effect of metoprolol combined with atractylenolide I (Atr I) in acute myocardial infarction (AMI) by regulating the SIRT3 (silent information regulator 3)/β-catenin/peroxisome proliferator-activated receptor gamma (PPAR-γ) signaling pathway. Briefly, 50 rats...
Abstract We aimed to compare the effects of oxycodone hydrochloride and dezocine on hemodynamics and inflammatory factors in patients receiving gynecological laparoscopic surgery under general anesthesia. A total of 246 patients were divided into group A and B (n=123). Hemorheology indices were recorded ...
Santos, Thais Menezes dos;
Sousa, Danieli Silva Feijó de;
Di Piero, Karina Chamma;
Todeschini, Adriane Regina;
Dias, Wagner Barbosa;
Oliveira, Catarina Amorim;
Santos, Elisabete Pereira dos;
Monteiro, Mariana Sato de Souza Bustamante;
Gomes, Maria Kátia;
Moura, Cristiano dos Reis;
Teixeira, Pedro Antônio Castelo;
Ricci-Junior, Eduardo;
Freitas, Zaida Maria Faria de.
Abstract Hydrogels are used for wound treatment, as they may contain one or more active components and protect the wound bed. Papain is one of the active substances that have been used with this purpose, alongside urea. In this paper, carboxypolymethylene hydrogels containing papain (2% and 10% concentra...
O presente trabalho tem como objeto de análise os usos e sentidos das práticas de treinamento cerebral na realidade brasileira. Este tipo de treinamento, também chamado de treinamento cognitivo e ginástica cerebral, diz respeito à prática guiada de determinados exercícios e jogos com o objetivo de...
Abstract Betamethasone (BET) is a synthetic glucocorticoid recommended for pregnant women at imminent risk of preterm birth before 34 weeks to reduce neonatal complications. There are different techniques to describe BET plasma quantification. However, none quantified the plasmatic concentration of BET ...
Jovanović, Marija;
Kovačević, Milena;
Catić-Đorđević, Aleksandra;
Ćulafić, Milica;
Stefanović, Nikola;
Mitić, Branka;
Vučićević, Katarina;
Kovačević, Sandra Vezmar;
Veličković-Radovanović, Radmila;
Miljković, Branislava.
Abstract The study aimed to estimate and compare the prevalence and type of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) between the STOPP/START original (v1) and updated version (v2) among older patients in various settings, as well as associated factors. The ...