Araujo, Zaida;
Palacios, Andrea;
Enciso-Moreno, Leonor;
Lopez-Ramos, Juan Ernesto;
Wide, Albina;
Waard, Jacobus Henri de;
Rivas-Santiago, Bruno;
Serrano, Carmen Judith;
Bastian-Hernandez, Yadira;
Castañeda-Delgado, Julio Enrique;
Enciso-Moreno, Jose Antonio.
Abstract INTRODUCTION: Biomarkers are critical tools for finding new approaches for controlling the spread of tuberculosis (TB), including for predicting the development of TB therapeutics, vaccines, and diagnostic tools. METHODS: Expression of immune biomarkers was analyzed in peripheral blood cells...
ABSTRACT Objective: Pneumonia is a leading cause of mortality worldwide, especially in the elderly. The use of clinical risk scores to determine prognosis is complex and therefore leads to errors in clinical practice. Pneumonia can cause increases in the levels of cardiac biomarkers such as N-terminal ...
Biomarcadores/sangre,
Infecciones Comunitarias Adquiridas/sangre,
Infecciones Comunitarias Adquiridas/mortalidad,
Unidades de Cuidados Intensivos,
Tiempo de Internación,
Modelos Logísticos,
Análisis Multivariante,
Péptido Natriurético Encefálico/sangre,
Fragmentos de Péptidos/sangre,
Neumonía/sangre,
Neumonía/mortalidad,
Valor Predictivo de las Pruebas,
Pronóstico,
Estudios Prospectivos,
Curva ROC,
Valores de Referencia,
Medición de Riesgo,
Factores de Riesgo,
Índice de Severidad de la Enfermedad,
Estadísticas no Paramétricas
Abstract Purpose: To compare open Lichtenstein repair and laparoscopic transabdominal preperitoneal (TAPP) repair to treat primary unilateral hernia, regarding systemic inflammatory response, postoperative pain, and complications. Methods: A non-randomized prospective cohort study, with the preoperati...
Biomarcadores/sangre,
Proteína C-Reactiva,
Hernia Inguinal/sangre,
Hernia Inguinal/cirugía,
Herniorrafia/efectos adversos,
Herniorrafia/métodos,
Interleucina-6,
Laparoscopía/efectos adversos,
Laparoscopía/métodos,
Tiempo de Internación,
Ensayos Clínicos Controlados no Aleatorios como Asunto,
Tempo Operativo,
Dolor Postoperatorio/sangre,
Estudios Prospectivos,
Síndrome de Respuesta Inflamatoria Sistémica/sangre,
Resultado del Tratamiento,
Escala Visual Analógica
Abstract Purpose Coleus forskohlii Briq., a medicinal plant originally from India, has been indicated against heart disease, expiratory disorders, convulsions, and hepatic changes, among others. In view of the broad pharmacological potential of the plant and the scarce information about its effects, the...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Aspartato Aminotransferasas/sangre,
Biomarcadores/sangre,
Hepatectomía/métodos,
Hepatocitos/efectos de los fármacos,
Hiperplasia/tratamiento farmacológico,
Hígado/efectos de los fármacos,
Hígado/patología,
Hígado/cirugía,
Extractos Vegetales/administración & dosificación,
Plectranthus/química
RESUMO Objetivo Este estudo teve como objetivo determinar os níveis séricos de proteína 3 contendo um domínio NACHT, porção C-terminal rica em repetições de leucina e de domínio pirina (NLRP3) e catelicidina LL-37, bem como investigar sua importância prognóstica em pneumonia adquirida na comu...
Péptidos Catiónicos Antimicrobianos/sangre,
Biomarcadores/sangre,
Estudios de Casos y Controles,
Infecciones Comunitarias Adquiridas/sangre,
Infecciones Comunitarias Adquiridas/mortalidad,
Estimación de Kaplan-Meier,
Modelos Logísticos,
Análisis Multivariante,
Proteína con Dominio Pirina 3 de la Familia NLR/sangre,
Neumonía/sangre,
Neumonía/mortalidad,
Valor Predictivo de las Pruebas,
Estudios Prospectivos,
Proteínas/análisis,
Pirina/sangre
Dexmedetomidine (DEX), a selective agonist of α2-adrenergic receptors, has anti-inflammation properties and potential beneficial effects against trauma, shock, or infection. Therefore, this study aimed to investigate whether DEX might protect against multiple-organ dysfunction in a two-hit model of ...
Biomarcadores/sangre,
Dexmedetomidina/uso terapéutico,
Modelos Animales de Enfermedad,
Endotoxemia/tratamiento farmacológico,
Endotoxemia/patología,
Hemorragia/tratamiento farmacológico,
Hemorragia/patología,
Insuficiencia Multiorgánica/tratamiento farmacológico,
Insuficiencia Multiorgánica/patología,
Estrés Oxidativo/efectos de los fármacos,
Sustancias Protectoras/uso terapéutico,
Ratas Wistar,
Receptores Adrenérgicos beta 2/efectos de los fármacos,
Receptores Adrenérgicos beta 2/metabolismo,
Resucitación,
Factores de Tiempo
Toledo, Beatriz;
Corral, Marcelo A;
Meisel, Dirce Mary C L;
Gottardi, Maiara;
Abdala, Edson;
Costa, Silvia F;
Pierrotti, Lígia Camera;
Lescano, Susana A Z;
Gonçalves, Elenice M N;
Castilho, Vera L P;
Chieffi, Pedro P;
Gryschek, Ronaldo C B;
Paula, Fabiana M.
OBJECTIVES: Hyperinfection or disseminated strongyloidiasis has been frequently reported after transplants and is related to high mortality. This study aimed to screen for strongyloidiasis using serological diagnoses in transplant candidates. METHODS: An ELISA test was performed with filariform larvae o...
Anticuerpos Antihelmínticos/sangre,
Antígenos Helmínticos/inmunología,
Antígenos Helmínticos/aislamiento & purificación,
Biomarcadores/sangre,
Ensayo de Inmunoadsorción Enzimática,
Huésped Inmunocomprometido,
Inmunoglobulina G/sangre,
Tamizaje Masivo,
Trasplante de Órganos,
Sensibilidad y Especificidad,
Strongyloides stercoralis/inmunología,
Estrongiloidiasis/diagnóstico,
Estrongiloidiasis/parasitología
Acute coronary syndromes are associated with a high prevalence of complications including heart failure (HF). The aim of this study was to investigate the association of novel biomarkers with the occurrence of post-acute myocardial infarction (AMI) HF. A prospective study was conducted with patients admi...
Falcão, F J A;
Oliveira, F R A;
Cantarelli, F;
Cantarelli, R;
Brito-Júnior, P;
Lemos, H;
Silva, P;
Camboim, I;
Freire, M C;
Carvalho, O;
Sobral-Filho, D C.
Carbohydrate antigen 125 (CA125) has long been used as an ovarian cancer biomarker. However, because it is not specific for ovarian cells, CA125 could also be used to monitor congestion and inflammation in heart disease. Acute heart failure (HF) is used to identify patients with a worse prognosis in ST-s...
Biomarcadores/sangre,
Antígeno Ca-125/sangre,
Estudios Transversales,
Valor Predictivo de las Pruebas,
Edema Pulmonar/sangre,
Edema Pulmonar/diagnóstico,
Edema Pulmonar/etiología,
Curva ROC,
Factores de Riesgo,
Infarto del Miocardio con Elevación del ST,
Infarto del Miocardio con Elevación del ST/complicaciones
ABSTRACT Objective: To evaluate intervertebral disc levels of inflammatory factor (interleukin 6) and proteinase activity (cathepsin B) in patients with a degenerative disease and serum levels of interleukin 6, serum cathepsin B activity and hyaluronic acid biomarkers. Methods: We conducted immunohisto...
Adyuvantes Inmunológicos/sangre,
Análisis de Varianza,
Biomarcadores/sangre,
Estudios de Casos y Controles,
Catepsina B/sangre,
Ácido Hialurónico/sangre,
Inmunohistoquímica,
Mediadores de Inflamación/sangre,
Interleucina-6/sangre,
Disco Intervertebral/fisiopatología,
Degeneración del Disco Intervertebral/sangre,
Degeneración del Disco Intervertebral/diagnóstico,
Degeneración del Disco Intervertebral/fisiopatología,
Estudios Prospectivos,
Sensibilidad y Especificidad
