Results: 3722

Tadalafil-loaded PLGA microspheres for pulmonary administration: preparation and evaluation

Tadalafil, a long-acting PED-5 inhibitor, is commonly used for the treatment of pulmonary arterial hypertension (PAH). However, its efficacy and clinical application are severely limited by the poor water solubility, low bioavailability and a series adverse effects (e.g. headaches, indigestion). In this ...

Adaptación y validación de la escala de mishel de incertidumbre frente a la enfermedad en procedimientos diagnósticos
Adaptation and validation of mishel)s scale of uncertainty against disease in diagnostic procedures

Cienc. enferm; 25 (), 2019
RESUMEN La incertidumbre es un estado que puede estar presente en las personas cuando experimentan una enfermedad y es probable que se encuentre en su mayor grado en el momento del diagnóstico de esa enfermedad. Objetivo: Adaptar y validar la Escala de Incertidumbre frente a la Enfermedad en pacientes q...

Challenges in measuring angles between craniofacial structures

J. appl. oral sci; 27 (), 2019
Abstract Objective: Three-dimensional (3D) angular measurements between craniofacial planes pose challenges to quantify maxillary and mandibular skeletal discrepancies in surgical treatment planning. This study aims to compare the reproducibility and reliability of two modules to measure angles between ...

Micro-CT evaluation of apical enlargement of molar root canals using rotary or reciprocating heat-treated NiTi instruments

J. appl. oral sci; 27 (), 2019
Abstract Objective The aim of this study was to evaluate the root canal preparation and apical enlargement of molar root canals with rotary or reciprocating heat-treated nickel-titanium (NiTi) instruments, by using micro-computed tomography (micro-CT). Methodology Mesial root canals (n=48) of mandibu...

Dual-task demands in various motor skills through Parkinson's disease progression

Motriz (Online); 25 (1), 2019
Aim: The aim of this study was to investigate the effects of adding a cognitive task on the performance of three different motor tasks with different demands, discrete skills, serial skills and continuous skills, by individuals with mild, moderate, and severe idiopathic Parkinson’ disease (PD). We als...

Influence of age, sex, and visual information on postural control in children

Motriz (Online); 25 (1), 2019
Aim: This study aims to evaluate and identify the influence of age, sex, and visual information on postural control in children. Methods: Participants were 62 children (30 boys and 32 girls) divided into the following age groups (G): G1, aged 5-6 years (n = 23); G2, aged 7-8 years (n = 21); and G3, ag...

Use of CMAP tools® software to teaching muscle contraction: an experience with undergraduates students in physical education

Motriz (Online); 25 (1), 2019
Aim: To evaluate the use of CMAP tools® software as a teaching strategy of skeletal muscle components and contraction in undergraduates students of physical education. Methods: Nineteen students from the discipline of fundamentals of human physiology of the undergraduate course of physical education ...

Effects of concurrent training associated with N-acetylcysteine on bone density of spontaneously hypertensive rats

Motriz (Online); 25 (2), 2019
Abstract Aim: The present study aimed to analyze the effects of N-acetylcysteine supplementation associated with concurrent training on the bone mineral density of spontaneously hypertensive elderly rats. Methods: For the present study, 28 male spontaneously hypertensive rats, six months old, were di...

Efficacy of sonic and ultrasonic irrigation devices in the removal of debris from canal irregularities in artificial root canals

J. appl. oral sci; 27 (), 2019
Abstract Objective To evaluate the efficacy of different sonic and ultrasonic devices in the elimination of debris from canal irregularities in artificial root canals. Materials and Methods A resin model of a transparent radicular canal filled with dentin debris was used. Five groups were tested, namel...

Microdatasus: pacote para download e pré-processamento de microdados do Departamento de Informática do SUS (DATASUS)

O objetivo do estudo foi desenvolver um algoritmo capaz de realizar o download e o pré-processamento de microdados fornecidos pelo Departamento de Informática do SUS (DATASUS) para diversos sistemas de informações em saúde para a linguagem de programação estatística R. O pacote desenvolvido permi...