Abstract The aim of the current study was to assess the physicochemical characteristics and wound healing activity of chitosan-polyvinyl alcohol (PVA) crosslinked hydrogel containing recombinant human epidermal growth factor (rh-EGF) or recombinant mouse epidermal growth factor (rm-EGF). The hydrogels we...
Abstract Objective: To compare the high-cycle fatigue behavior of four commercially available NiTi orthodontic wires. Material and Methods: Twelve NiTi orthodontic wires, round, 0.016-in, three per brand, were selected and divided into four groups: G1 - Heat-activated NiTi, G2 - Superelastic NiTi, G3 -...
Rodrigues, Gabriella Fernandes;
Monteiro, Amanda Souza Nunes;
Vollú, Ana Lúcia;
Pires, Paula Maciel;
Silva, Aline Saddock de Sá;
Lopes, Ricardo Tadeu;
Oliveira, Branca Heloisa;
Neves, Aline de Almeida;
Barja-Fidalgo, Fernanda;
Fonseca-Gonçalves, Andréa.
Abstract Objective: To evaluate the efficacy of silver diamine fluoride (SDF) in arresting dentin caries lesions when applied under different concentrations and times. Material and Methods: Forty-two bovine blocks were selected and fixed in 24-well plates. Each well received a mixed bacterial inoculum ...
Estadísticas no Paramétricas,
Técnicas In Vitro/métodos,
Caries Dental/epidemiología,
Cariostáticos/uso terapéutico,
Dentina,
Estudios Longitudinales,
Remineralización Dental,
Diaminas/química,
Fluoruros/química,
Microtomografía por Rayos X/instrumentación,
Plata/uso terapéutico,
Biopelículas
Abstract Objective: To assess the antibacterial activity of Psidium guajava fractions and their effects on adhesion of a multispecies biofilm consisting of Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis in vitro. Material and Methods: Guava leaves were obtained from the m...
Abstract In the hospital environment, postoperative pain is a common occurrence that impairs patient recovery and rehabilitation and lengthens hospitalization time. Racemic bupivacaine hydrochloride (CBV) and Novabupi® (NBV) (S (-) 75% R (+) 25% bupivacaine hydrochloride) are two examples of local anest...
Abstract Despite decades of research, wound healing remains a significant public health problem. This study aimed to develop and evaluate a topical sodium alginate gel containing vancomycin (Van) loaded MMT NPs for wound healing applications. Van was loaded in MMT at different conditions (pHs of 6, 7 and...
Técnicas In Vitro/métodos,
Vancomicina/agonistas,
Infección de Heridas/patología,
Alginatos/análisis,
Bentonita/antagonistas & inhibidores,
Cicatrización de Heridas/efectos de los fármacos,
Antibacterianos/clasificación,
ddcs0285700,
Espectroscopía Infrarroja por Transformada de Fourier/métodos,
Heridas y Lesiones/tratamiento farmacológico,
d0121060,
Preparaciones Farmacéuticas/administración & dosificación
Abstract Serrapeptase, a proteolytic enzyme, has been used for the adjuvant treatment of many diseases. However, its fibrinolytic activity is still uncertain. Herein, the fibrinolytic activity of serrapeptase and its in vitro thrombolytic effects were investigated. The results showed that the fibrinolyti...
Abstract Quality is paramount and needs to be maintained throughout the shelf life of pharmaceuticals. The current study aimed to evaluate the quality, potency, and drug-drug interaction in an in vivo animal model by using two drugs, namely, metoprolol and glimepiride. Tablets were selected for their phy...
Abstract The present research evaluated the anti urolithic potential of Cyperus rotundus tubers extract using in silico, in vitro and in vivo techniques. In silicostudy was performed of Cyperus rotundus constituents and pathological protein oxalate oxidase (PDB Id: 2ETE). In vitrostudy, nucleation and ag...
Tubérculos de la Planta/clasificación,
Cyperus/efectos adversos,
Extractos Vegetales/análisis,
Técnicas In Vitro/métodos,
Urolitiasis/inducido químicamente,
Antioxidantes/farmacología,
Id,
d0036270,
Oxalato de Calcio/agonistas,
Programas Informáticos/clasificación,
Aceites Volátiles/efectos adversos
Abstract A phytochemical study of Tecoma genus (Bignoniaceae) was accomplished by antitumor activity of ethanolic extracts. Species of this genus are composed of small shrubs often used as ornamental plants. The Tecoma stans species is used in folk medicine for different purposes. Recent work shows in vi...