Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread around the world during 2020, but the precise time in which the virus began to spread locally is difficult to trace for most countries. Here, we estimate the probable onset date of the community spread of SARS-CoV-2 for heavily a...
Américas/epidemiología,
Betacoronavirus,
COVID-19,
Infecciones Comunitarias Adquiridas/epidemiología,
Infecciones Comunitarias Adquiridas/transmisión,
Infecciones Comunitarias Adquiridas/virología,
Infecciones por Coronavirus/epidemiología,
Infecciones por Coronavirus/transmisión,
Europa (Continente)/epidemiología,
Pandemias,
Neumonía Viral/epidemiología,
Neumonía Viral/transmisión,
SARS-CoV-2
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious infection that may break the healthcare system of several countries. Here, we aimed at presenting a critical view of ongoing drug repurposing efforts for COVID-19 as well ...
Nascimento, Valdinete Alves do;
Corado, André de Lima Guerra;
Nascimento, Fernanda Oliveira do;
Costa, Ágatha Kelly Araújo da;
Duarte, Debora Camila Gomes;
Luz, Sérgio Luiz Bessa;
Gonçalves, Luciana Mara Fé;
Jesus, Michele Silva de;
Costa, Cristiano Fernandes da;
Delatorre, Edson;
Naveca, Felipe Gomes.
A new coronavirus [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] is currently causing a life-threatening pandemic. In this study, we report the complete genome sequencing and genetic characterisation of a SARS-CoV-2 detected in Manaus, Amazonas, Brazil, and the protocol we designed to gen...
Infecciones Asintomáticas,
Betacoronavirus/genética,
Brasil,
COVID-19,
Infecciones por Coronavirus/virología,
Genoma Viral,
Genómica,
Mutación,
Pandemias,
Filogenia,
Filogeografía,
Neumonía Viral/virología,
SARS-CoV-2,
España
Chagas, Aline Lopes;
da Fonseca, Leonardo Gomes;
Coelho, Fabricio Ferreira;
da Cunha Saud, Lisa Rodrigues;
Abadala, Edson;
Andraus, Wellington;
Fiore, Lucas;
Moreira, Airton Mota;
Menezes, Marcos Roberto;
Carnevale, Francisco César;
Tani, Claudia Megumi;
Alencar, Regiane S S M;
DAlbuquerque, Luiz Augusto Carneiro;
Herman, Paulo;
Carrilho, Flair José.
More than 18 million people in 188 countries have been diagnosed as having coronavirus disease (COVID-19), and COVID-19 has been responsible for more than 600,000 deaths worldwide. Brazil is now the second most affected country globally. Faced with this scenario, various public health measures and change...
Betacoronavirus,
Brasil/epidemiología,
COVID-19,
Carcinoma Hepatocelular/epidemiología,
Carcinoma Hepatocelular/terapia,
Consenso,
Infecciones por Coronavirus,
Neoplasias Hepáticas/epidemiología,
Neoplasias Hepáticas/terapia,
Pandemias,
Neumonía Viral,
SARS-CoV-2
OBJECTIVES: Previous studies focusing on pediatric patients hospitalized with severe coronavirus disease 2019 (COVID-19) have been limited to small case series. We aimed to evaluate the characteristics of a large population of pediatric patients with severe COVID-19 and compare them with patients with se...
Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), became a pandemic in March 2020, affecting millions of people worldwide. However, COVID-19 in pediatric patients represents 1-5% of all cases, and the risk for developing severe disease and critical il...
Objetivo: Descrever o perfil dos óbitos e a letalidade de síndrome respiratória aguda grave (SRAG) por COVID-19 em crianças e adolescentes hospitalizados no Brasil. Métodos: Estudo transversal, realizado com dados das fichas de notificação de SRAG de crianças e adolescentes (0 a 19 anos) com con...
Infecciones por Coronavirus/complicaciones,
Infecciones por Coronavirus/epidemiología,
Infecciones por Coronavirus/mortalidad,
Mortalidad Hospitalaria,
Hospitalización/estadística & datos numéricos,
Síndrome Respiratorio Agudo Grave/epidemiología,
Síndrome Respiratorio Agudo Grave/mortalidad,
Betacoronavirus/clasificación,
Estudios Transversales,
Pandemias/estadística & datos numéricos,
Monitoreo Epidemiológico,
Brasil/epidemiología
Amorim Filho, Luiz;
Szwarcwald, Célia Landmann;
Mateos, Sheila de Oliveira Garcia;
Leon, Antonio Carlos Monteiro Ponce de;
Medronho, Roberto de Andrade;
Veloso, Valdiléa Gonçalves;
Lopes, Josiane Iole França;
Porto, Luis Cristovão de Moraes Sobrino;
Chieppe, Alexandre;
Werneck, Guilherme Loureiro.
ABSTRACT OBJECTIVE To estimate the seroprevalence of antibodies to SARS-CoV-2 among blood donors in the state of Rio de Janeiro, Brazil. METHODS Data were collected on 2,857 blood donors from April 14 to 27, 2020. This study reports crude prevalence of antibodies to SARS-CoV-2, population weighted prev...
Anticuerpos Antivirales/sangre,
Betacoronavirus/inmunología,
Donantes de Sangre/estadística & datos numéricos,
Brasil/epidemiología,
COVID-19,
Infecciones por Coronavirus/sangre,
Infecciones por Coronavirus/epidemiología,
Infecciones por Coronavirus/inmunología,
Estudios Transversales,
Inmunoglobulina G/sangre,
Inmunoglobulina M/sangre,
Persona de Mediana Edad,
Pandemias,
Neumonía Viral/sangre,
Neumonía Viral/epidemiología,
Neumonía Viral/inmunología,
Prevalencia,
Análisis de Regresión,
SARS-CoV-2,
Sensibilidad y Especificidad,
Estudios Seroepidemiológicos
ABSTRACT OBJECTIVE To describe the dietary characteristics of participants in the NutriNet Brasil cohort immediately before and during the covid-19 pandemic. METHODS Our data stem from an adult cohort created to prospectively investigate the relationship between diet and morbidity and mortality from ch...
Betacoronavirus,
Brasil,
COVID-19,
Estudios de Cohortes,
Infecciones por Coronavirus/epidemiología,
Dieta/tendencias,
Morbilidad,
Enfermedades no Transmisibles/mortalidad,
Pandemias,
Neumonía Viral/epidemiología,
SARS-CoV-2
ABSTRACT Chloroquine (CQ) and its analog hydroxychloroquine (HCQ) were recently included in several clinical trials as potential prophylactic and therapeutic options for SARS-COV-2 infection/covid-19. However, drug effectiveness in preventing, treating, or slowing the progression of the disease is still ...
Antimaláricos/efectos adversos,
Antimaláricos/farmacocinética,
Antimaláricos/farmacología,
Betacoronavirus/efectos de los fármacos,
COVID-19,
Cloroquina/efectos adversos,
Cloroquina/farmacocinética,
Cloroquina/farmacología,
Contraindicaciones de los Medicamentos,
Infecciones por Coronavirus/tratamiento farmacológico,
Hidroxicloroquina/efectos adversos,
Hidroxicloroquina/farmacocinética,
Hidroxicloroquina/farmacología,
Pandemias,
Neumonía Viral/tratamiento farmacológico,
Medición de Riesgo,
SARS-CoV-2
