Abstract: Specific variants in genes that encode adipokines and their mRNA and protein expression were previously studied in type 2 diabetes mellitus (T2DM) and obesity, and similar studies have been performed for chronic periodontitis (CP). The aim of this case-control study was to investigate the possi...
Adipoquinas/sangre,
Adipoquinas/genética,
Análisis de Varianza,
Biomarcadores/sangre,
Estudios de Casos y Controles,
Periodontitis Crónica/sangre,
Periodontitis Crónica/genética,
Diabetes Mellitus Tipo 2/sangre,
Diabetes Mellitus Tipo 2/genética,
Variación Genética,
Genotipo,
Persona de Mediana Edad,
Polimorfismo de Nucleótido Simple,
Valores de Referencia,
Estadísticas no Paramétricas
OBJECTIVES: We aimed to explore the effects of diet on the inflammatory response in middle-aged and elderly people with hypertension. METHODS: Thirty overweight or obese patients with stage one hypertension (age range, 45-75 years) were allocated to either the intervention or control group (n=15 per gro...
Adiponectina/sangre,
Biomarcadores/sangre,
Presión Sanguínea/efectos de los fármacos,
Proteína C-Reactiva/análisis,
China,
Suplementos Dietéticos/análisis,
Ingestión de Energía,
Hipertensión/sangre,
Inflamación/sangre,
Molécula 1 de Adhesión Intercelular/sangre,
FN-kappa B/sangre,
Encuestas Nutricionales/estadística & datos numéricos,
Sobrepeso/sangre,
Polvos/uso terapéutico,
Población Rural
OBJECTIVES: The inflammatory response is a key mechanism of neuronal damage and loss during acute ischemic stroke. Hypothermia has shown promise as a treatment for ischemic stroke. In this study, we investigated the molecular signaling pathways in ischemic stroke after hypothermia treatment. METHODS: Cy...
Enfermedad Aguda,
Biomarcadores/sangre,
Western Blotting,
Isquemia Encefálica/sangre,
Isquemia Encefálica/terapia,
Quinasa 5 Dependiente de la Ciclina/sangre,
Modelos Animales de Enfermedad,
Ensayo de Inmunoadsorción Enzimática,
Hipotermia Inducida/métodos,
Inflamación/sangre,
Interleucina-1beta/sangre,
FN-kappa B/sangre,
Ratas Sprague-Dawley,
Resultado del Tratamiento
Pregnancy of unknown location is a situation in which a positive pregnancy test occurs, but a transvaginal ultrasound does not show intrauterine or ectopic gestation. One great concern of pregnancy of unknown location is that they are cases of ectopic pregnancy whose diagnosis might be postponed. Transva...
Teixeira, R S;
Arriaga, M B;
Terse-Ramos, R;
Ferreira, T A;
Machado, V R;
Rissatto-Lago, M R;
Silveira-Mattos, P S;
Boa-Sorte, N;
Ladeia, A M T;
Andrade, B B.
Dyslipidemia has been described in sickle cell anemia (SCA) but its association with increased disease severity is unknown. Here, we examined 55 children and adolescents with SCA as well as 41 healthy controls to test the association between the lipid profiles in peripheral blood and markers of hemolysis...
Regucalcin is a soluble protein that is principally expressed in hepatocytes. Studies of regucalcin have mainly been conducted in animals due to a lack of commercially available kits. We aimed to develop an enzyme-linked immunosorbent assay (ELISA) to quantify serum regucalcin in patients with hepatitis ...
Anticuerpos Antivirales/inmunología,
Biomarcadores/sangre,
Proteínas de Unión al Calcio/sangre,
Estudios de Casos y Controles,
Ensayo de Inmunoadsorción Enzimática/métodos,
Hepatitis B Crónica/sangre,
Hepatitis B Crónica/virología,
Insuficiencia Renal/sangre,
Insuficiencia Renal/virología,
Reproducibilidad de los Resultados,
Sensibilidad y Especificidad,
Índice de Severidad de la Enfermedad
Vitoria, Webster Oliveira;
Thomé, Letícia Silva;
Kanashiro-Galo, Luciane;
Carvalho, Leda Viegas de;
Penny, Ricardo;
Santos, Washington Luis Conrado;
Vasconcelos, Pedro Fernando da Costa;
Sotto, Mirian Nacagami;
Duarte, Maria Irma Seixas;
Quaresma, Juarez Antonio Simões;
Pagliari, Carla.
Abstract INTRODUCTION: Dengue is an important mosquito-borne disease in tropical and subtropical regions. Adhesion molecules have not been systematically characterized in the renal tissue of patients with severe dengue (SD). The objective of this study was to detect viral antigens in samples from patie...
Antígenos CD/sangre,
Antígenos CD/fisiología,
Antígenos Virales/sangre,
Biomarcadores/sangre,
Cadherinas/sangre,
Cadherinas/fisiología,
Progresión de la Enfermedad,
Selectina E/sangre,
Selectina E/fisiología,
Endotelio/fisiopatología,
Inmunohistoquímica,
Molécula 1 de Adhesión Intercelular/sangre,
Molécula 1 de Adhesión Intercelular/fisiología,
Persona de Mediana Edad,
Dengue Grave/sangre,
Dengue Grave/fisiopatología,
Regulación hacia Arriba,
Molécula 1 de Adhesión Celular Vascular/sangre,
Molécula 1 de Adhesión Celular Vascular/fisiología
Abstract Purpose: To evaluate the cardioprotective response of the pharmacological modulation of β-adrenergic receptors (β-AR) in animal model of cardiac ischemia and reperfusion (CIR), in spontaneously hypertensive (SHR) and normotensive (NWR) rats. Methods: CIR was induced by the occlusion...
Antagonistas de Receptores Adrenérgicos beta 1/farmacología,
Agonistas Adrenérgicos beta/farmacología,
Atenolol/farmacología,
Biomarcadores/sangre,
Presión Sanguínea/efectos de los fármacos,
Cardiotónicos/farmacología,
Forma MB de la Creatina-Quinasa/sangre,
Pruebas de Función Cardíaca,
Isoproterenol/farmacología,
Daño por Reperfusión Miocárdica/sangre,
Daño por Reperfusión Miocárdica/tratamiento farmacológico,
Daño por Reperfusión Miocárdica/fisiopatología,
Ratas Endogámicas SHR,
Receptores Adrenérgicos beta/efectos de los fármacos,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Resultado del Tratamiento
Abstract Background: Recommendations of the Myopathy Committee of the Brazilian Society of Rheumatology for the management and therapy of systemic autoimmune myopathies (SAM). Main body: The review of the literature was done in the search for the Medline (PubMed), Embase and Cochrane databases includin...
Enfermedades Autoinmunes/tratamiento farmacológico,
Glucocorticoides/uso terapéutico,
Inmunosupresores/uso terapéutico,
Enfermedades Musculares/tratamiento farmacológico,
Enfermedades Autoinmunes/rehabilitación,
Biomarcadores/Sangre,
Brasil,
Dermatomiositis/terapia,
Ejercicio Físico,
Terapia por Ejercicio,
Glucocorticoides/efectos adversos,
Inmunoglobulinas Intravenosas/uso terapéutico,
Inmunosupresores/efectos adversos,
Metilprednisolona/administración & dosificación,
Metilprednisolona/efectos adversos,
Enfermedades Musculares/rehabilitación,
Educación del Paciente como Asunto,
Polimiositis/terapia,
Prednisona/administración & dosificación,
Prednisona/efectos adversos,
Ensayos Clínicos Controlados Aleatorios como Asunto,
Reumatología,
Rituximab/uso terapéutico,
Sociedades Médicas
Vascular surgery is considered high risk, due to the characteristics of patients and surgical procedures. Recently, the diagnosis of myocardial injury after non-cardiac surgery (MINS) was introduced to focus attention on the prognostic relevance of elevated ischemic troponin after non-cardiac surgery. In...
