Results: 571

DEC1: a potential biomarker of malignant transformation in oral leukoplakia

Abstract The purpose of this study was to analyze the differential expression of DEC1 in oral normal mucosa (NM), oral leukoplakia (OLK) and oral squamous cell carcinoma (OSCC). Surgically excised specimens from patients with OLK (n = 47), OSCC (n = 30) and oral normal mucosa (n=11) were immunostained fo...

Avaliação dos efeitos do Bisfenol A em queratinócitos e células de neoplasia de cavidade oral

O Bisfenol A (BPA) é um monômero utilizado na produção de garrafas plásticas, embalagens alimentícias, resinas odontológicas e vários outros materiais. Este monômero age como um desregulador do sistema endócrino e seus efeitos estão associados a cânceres em diferentes órgão e tecidos, como ...

Tobacco and Alcohol Use and Clinical Staging of Head and Neck Tumors

Abstract Objective: To determine the relationship between tobacco and alcohol consumption and staging of head and neck cancer in patients treated at a referral hospital for cancer treatment. Material and Methods: This is a cross-sectional study based on medical records of patients with head and neck ca...

Smoking-Alcohol-Sex Exposure and Knowledge About Oral and Oropharyngeal Cancer Among Brazilian Adolescents: An Exploratory-Observational Approach

Abstract Objective: To investigate the involvement of young Brazilian students about five behaviors: tobacco use, alcohol consumption, sexual intercourse, knowledge about HPV, and knowledge about oral and oropharyngeal cancer. Material and Methods: Through a cross-section design, we explored some facto...

Evaluation of lymphocyte apoptosis in patients with oral cancer

J. appl. oral sci; 28 (), 2020
Abstract Objectives To evaluate apoptotic levels of peripheral blood mononuclear cells (PBMCs) and apoptotic regulatory proteins (Bax and Bcl-2) in lymphocyte subsets of oral cancer (OC) patients and healthy controls (HC). Methodology The percentage of apoptotic cells and lymphocyte counts were measu...

Prevalence of oral potentially malignant disorders associated with habits in Puducherry - a Cross-sectional study

Braz. j. oral sci; 19 (), 2020
Tobacco and betel quid are the most common cause of oral cancer in India. Very often oral cancers are preceded by a visible oral precursor lesion called as potentially malignant disorder (PMD). Aim: The aim of this study was to assess the prevalence of oral PMDs associated with habits in urban and rural ...

Precisión diagnóstica de biomarcadores salivales para cáncer oral y desórdenes potencialmente malignos: protocolo de revisión sistemática

Medwave; 20 (5), 2020
INTRODUCCIÓN: El cáncer oral tiene una tasa de supervivencia a los cinco años de 50%, debido a que frecuentemente su diagnóstico es realizado en estadios avanzados. Por lo tanto, son necesarias nuevas ayudas diagnósticas. Actualmente, existe un número significativo de publicaciones científicas sug...

Survival trends of patients with oral and oropharyngeal cancer treated at a cancer center in São Paulo, Brazil

Clinics; 75 (), 2020
OBJECTIVE: We aimed to estimate the overall survival (OS) and conditional survival (CS) in patients diagnosed with oral and oropharyngeal squamous cell carcinoma (SCC) and to determine their survival trends. METHODS: The study included all consecutive patients treated at the A.C. Camargo Cancer Center f...

The effect of Maras powder and smoking on the microRNA deregulation of oral mucosa

J. appl. oral sci; 28 (), 2020
Abstract Objective This study aimed to investigate the effects of Maras powder (a type of smokeless tobacco obtained from Nicotiana rustica Linn and mixed with the ashes of wood, especially from oak, walnut or grapevine) on the microRNA (miRNA) deregulation of oral mucosa, and it compares these effects...

How pathological criteria can impact prognosis of tongue and floor of the mouth squamous cell carcinoma

J. appl. oral sci; 28 (), 2020
Abstract Pathological parameters have been indicated as tumor prognostic factors in oral carcinoma. Objective: The objective of this study was to investigate the impact of pathological parameters on prognosis of patients affected only by tongue and/or floor of the mouth squamous cell carcinoma (SCC). M...