Abstract The purpose of this study was to analyze the differential expression of DEC1 in oral normal mucosa (NM), oral leukoplakia (OLK) and oral squamous cell carcinoma (OSCC). Surgically excised specimens from patients with OLK (n = 47), OSCC (n = 30) and oral normal mucosa (n=11) were immunostained fo...
Factores de Edad,
Análisis de Varianza,
Biomarcadores de Tumor/análisis,
Carcinoma de Células Escamosas/patología,
Transformación Celular Neoplásica/patología,
Inmunohistoquímica,
Leucoplasia Bucal/patología,
Persona de Mediana Edad,
Neoplasias de la Boca/patología,
Valores de Referencia,
Reproducibilidad de los Resultados,
Factores de Riesgo,
Estadísticas no Paramétricas,
Proteínas Supresoras de Tumor/análisis
O Bisfenol A (BPA) é um monômero utilizado na produção de garrafas plásticas,
embalagens alimentícias, resinas odontológicas e vários outros materiais. Este
monômero age como um desregulador do sistema endócrino e seus efeitos estão
associados a cânceres em diferentes órgão e tecidos, como ...
Abstract Objective: To determine the relationship between tobacco and alcohol consumption and staging of head and neck cancer in patients treated at a referral hospital for cancer treatment. Material and Methods: This is a cross-sectional study based on medical records of patients with head and neck ca...
Estudios Transversales/métodos,
Neoplasias de Cabeza y Cuello/patología,
Uso de Tabaco/efectos adversos,
Neoplasias de la Boca/patología,
Registros Médicos/estadística & datos numéricos,
Epidemiología Descriptiva,
Estudios Retrospectivos,
Distribución de Chi-Cuadrado,
Factores de Riesgo,
Consumo de Bebidas Alcohólicas/efectos adversos,
Trabajadores Rurales,
Brasil/epidemiología
Abstract Objective: To investigate the involvement of young Brazilian students about five behaviors: tobacco use, alcohol consumption, sexual intercourse, knowledge about HPV, and knowledge about oral and oropharyngeal cancer. Material and Methods: Through a cross-section design, we explored some facto...
Abstract Objectives To evaluate apoptotic levels of peripheral blood mononuclear cells (PBMCs) and apoptotic regulatory proteins (Bax and Bcl-2) in lymphocyte subsets of oral cancer (OC) patients and healthy controls (HC). Methodology The percentage of apoptotic cells and lymphocyte counts were measu...
Tobacco and betel quid are the most common cause of oral cancer in India. Very often oral cancers are preceded by a visible oral precursor lesion called as potentially malignant disorder (PMD). Aim: The aim of this study was to assess the prevalence of oral PMDs associated with habits in urban and rural ...
INTRODUCCIÓN: El cáncer oral tiene una tasa de supervivencia a los cinco años de 50%, debido a que frecuentemente su diagnóstico es realizado en estadios avanzados. Por lo tanto, son necesarias nuevas ayudas diagnósticas. Actualmente, existe un número significativo de publicaciones científicas sug...
OBJECTIVE: We aimed to estimate the overall survival (OS) and conditional survival (CS) in patients diagnosed with oral and oropharyngeal squamous cell carcinoma (SCC) and to determine their survival trends. METHODS: The study included all consecutive patients treated at the A.C. Camargo Cancer Center f...
Brasil/epidemiología,
Carcinoma de Células Escamosas/mortalidad,
Carcinoma de Células Escamosas/patología,
Estimación de Kaplan-Meier,
Neoplasias de la Boca/mortalidad,
Neoplasias de la Boca/patología,
Estadificación de Neoplasias,
Neoplasias Orofaríngeas/mortalidad,
Neoplasias Orofaríngeas/patología,
Pronóstico,
Modelos de Riesgos Proporcionales,
Estudios Retrospectivos,
Análisis de Supervivencia
Abstract Objective This study aimed to investigate the effects of Maras powder (a type of smokeless tobacco obtained from Nicotiana rustica Linn and mixed with the ashes of wood, especially from oak, walnut or grapevine) on the microRNA (miRNA) deregulation of oral mucosa, and it compares these effects...
Análisis de Varianza,
Estudios Transversales,
Regulación hacia Abajo,
Expresión Génica,
MicroARNs/análisis,
MicroARNs/efectos de los fármacos,
Mucosa Bucal/efectos de los fármacos,
Neoplasias de la Boca/genética,
Polvos,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Factores de Riesgo,
Factores de Tiempo,
Tabaco sin Humo/efectos adversos
Rodrigues, Renata Miranda;
Bernardo, Vagner Gonçalves;
Da Silva, Sabrina Daniela;
Camisasca, Danielle Resende;
Faria, Paulo Antônio de Silvestre;
Dias, Fernando Luiz;
Pinto, Luís Felipe Ribeiro;
Albano, Rodolpho Mattos;
Bergmann, Anke;
Lourenço, Simone de Queiroz Chaves.
Abstract Pathological parameters have been indicated as tumor prognostic factors in oral carcinoma. Objective: The objective of this study was to investigate the impact of pathological parameters on prognosis of patients affected only by tongue and/or floor of the mouth squamous cell carcinoma (SCC). M...
Carcinoma de Células Escamosas/mortalidad,
Carcinoma de Células Escamosas/patología,
Carcinoma de Células Escamosas/cirugía,
Supervivencia sin Enfermedad,
Estimación de Kaplan-Meier,
Suelo de la Boca/patología,
Neoplasias de la Boca/mortalidad,
Neoplasias de la Boca/patología,
Neoplasias de la Boca/cirugía,
Disección del Cuello/métodos,
Clasificación del Tumor/métodos,
Estadificación de Neoplasias,
Análisis de Regresión,
Factores de Tiempo,
Neoplasias de la Lengua/mortalidad,
Neoplasias de la Lengua/patología,
Neoplasias de la Lengua/cirugía