Results: 272

Inhibition of quorum sensing by compounds from two eunicea species and synthetic saturated alkylglycerols

Vitae (Medellín); 25 (2), 2018
Background: the emergence of bacterial resistance has led to a search for new natural products as alternatives starting points to prevent and control diseases caused by microorganisms. Among the potential candidates were bioactive compounds from octocorals of the genus Eunicea due to their chemical struc...

Evolución y logros de la Gerencia de Producción y Servicios Básicos del Instituto Nacional de Higiene “Rafael Rangel”
Evolution and achievements of the Production Management and Basic Services of the National Institute of Hygiene “Rafael Rangel”

Rev. Inst. Nac. Hig; 49 (1), 2018
La Gerencia de Producción y Servicios Básicos del INHRR responde a las necesidades de las áreas técnicas del Instituto a través de la producción de insumos requeridos para el control de productos de uso y consumo humano, diagnóstico de enfermedades transmisibles, desarrollo de nuevas técnicas y l...

Capítulo 2. Enfermedad de Crohn
Chapter 2. Crohn's disease

Determinación de la eficacia de los desinfectantes empleados en las áreas asépticas de un centro productor de biofarmacéuticos
Determination of the efficacy of the disinfectants employed in the aseptic areas at a biopharmaceuticals production center

En la industria biofarmacéutica, la desinfección se ha hecho parte fundamental de las actividades para controlar el nivel de microorganismos contaminantes que puedan llegar a comprometer la calidad del producto final. El objetivo de este trabajo fue evaluar la eficacia de los desinfectantes AniosSpecia...

Gestión del desarrollo de productos en el Centro de Inmunología Molecular
Product development management at Molecular Immunology Center

El crecimiento de las empresas en un mundo altamente competitivo depende del rendimiento superior del proceso de desarrollo de sus productos. Estudios anteriores mostraron que hoy la dificultad principal del crecimiento del Centro de Inmunología Molecular está en la capacidad de penetrar los mercados d...

Reevaluation of the Strain Pressure Theory: Toward a Better Understanding the Biology of Tooth Movement

The aim of this report was to analyze the majority of publications referred to orthodontic movement Biological basis, principally strain- pressure theory taking account contemporaneous methodological study designs. The literature published in Pubmed from 1967 to 2014 was reviewed, in addition to well-kno...

Cost-minimization and budget impact analysis of certolizumab pegol for patients with Crohn’s disease, moderate or severe, with relapse after conventional treatment from the perspective of the Brazilian private payer

Objectives: Budget impact and cost-effectiveness analysis are often required by payers when discussing drug reimbursement. We hereby present a cost-minimization (CMA) and budget impact analysis (BIA) regarding the incorporation of certolizumab pegol (CZP) for the treatment of patients with Crohn’s dise...

Selection, isolation, and identification of fungi for bioherbicide production

Braz. j. microbiol; 48 (1), 2017
Abstract Production of a bioherbicide for biological control of weeds requires a series of steps, from selection of a suitable microbial strain to final formulation. Thus, this study aimed to select fungi for production of secondary metabolites with herbicidal activity using biological resources of the B...

Itinerário terapêutico de pacientes com artrite reumatoide em uso de medicamentos modificadores do curso da doença biológicos

Introdução A artrite reumatoide (AR) é uma doença crônica autoimune degenerativa, de alta prevalência e alta morbimortalidade, com difícil diagnóstico em todo o mundo. O seu pronto diagnóstico e o rápido início com medicamentos modificadores do curso da doença (MMCD) impactam de forma relevan...

Síntese de heteroaril oxazolinas e derivados triazólicos com potencial atividade biológica

Fungos no ambiente podem ser patogênicos ou oportunistas, dependendo da imunidade do hospedeiro. Existem várias espécies de fungos, por exemplo, Cândida albicans, Cryptococcus e Aspergillus. A primeira espécie fúngica pode ser tratada com o antifúngico fluconazol, que é um composto que contém an...