Results: 1100
Mecanismo de Ação do Anti-hipertensivo Manidipino em Trypanosoma cruzi: Uma Abordagem de Reposicionamento de Fármaco
A doença de Chagas (DC), também conhecida como tripanossomíase americana, afeta cerca de 6 a 7 milhões de pessoas em todo o mundo, com aproximadamente 70 milhões de pessoas em áreas de risco. Causada pelo parasita Trypanosoma cruzi, a DC é um problema de saúde pública, ocorrendo do sul dos Estad...
Analyzing weight evolution in mice infected by Trypanosoma cruzi
Acta sci., Health sci; 42 (), 2020
Concerning the specificities of a longitudinal study, the trajectories of a subject's mean responses not always present a linear behavior, which calls for tools that take into account the non-linearity of individual trajectories and that describe them towards associat...
Ratones, Trayectoria del Peso Corporal, Trypanosoma cruzi/inmunología, Pesos y Medidas Corporales, Bioterápicos/antagonistas & inhibidores, Pollos, Suero/inmunología, Trypanosoma cruzi/parasitología, Enfermedad de Chagas/tratamiento farmacológico, Antígenos de Protozoos/inmunología, Anticuerpos Antiprotozoarios/inmunología, Ensayo Clínico Controlado Aleatorio Veterinario, Suero/parasitología
Use of tissue doppler imaging for the early detection of myocardial dysfunction in patients with the indeterminate form of Chagas disease
Rev. Soc. Bras. Med. Trop; 53 (), 2020
Abstract INTRODUCTION: Chagas disease is one of the most common diseases in Latin America and heart involvement is the main cause of death. This study aimed to determine differences in tissue Doppler imaging (TDI) parameters in the assessment left and right ventricular function in patients with the ind...
Estudios de Casos y Controles, Enfermedad de Chagas/diagnóstico por imagen, Enfermedad de Chagas/fisiopatología, Diagnóstico Precoz, Ecocardiografía, Ecocardiografía Doppler, Corazón/diagnóstico por imagen, Corazón/fisiopatología, Persona de Mediana Edad, Variaciones Dependientes del Observador, Disfunción Ventricular Izquierda/diagnóstico por imagen, Disfunción Ventricular Izquierda/fisiopatología
Actividad repelente del aceite esencial de Laurelia sempervirens (Ruiz & Pav.) Tul. (Monimiaceae) en Triatoma infestans (Klug)(Reduviidae)
Repellent activity of the essential oil from Laurelia sempervirens (Ruiz & Pav.) Tul. (Monimiaceae) on Triatoma infestans (Klug) (Reduviidae)
Bol. latinoam. Caribe plantas med. aromát; 19 (4), 2020
Triatoma infestans (Klug) es el vector principal de la enfermedad de Chagas en Bolivia y los países vecinos. El objetivo de este estudio fue determinar la composición química del AE del laurel chileno, Laurelia sempervirens (Ruiz & Pav.) Tul. (Monimiaceae) y evaluar su efecto repelente en ninfas del q...
Influence of Angiotensin-converting Enzyme Insertion/Deletion Gene Polymorphism in Progression of Chagas Heart Disease
Rev. Soc. Bras. Med. Trop; 53 (), 2020
Abstract INTRODUCTION: Chagas disease (CD) is a neglected disease caused by the parasite Trypanosoma cruzi. One-third of infected patients will develop the cardiac form, which may progress to heart failure (HF). However, the factors that determine disease progression remain unclear. Increased angiotens...
Inhibidores de la Enzima Convertidora de Angiotensina, Brasil, Estudios de Casos y Controles, Enfermedad de Chagas/genética, Enfermedad de Chagas/fisiopatología, Estudios de Cohortes, Progresión de la Enfermedad, Genotipo, Insuficiencia Cardíaca/genética, Insuficiencia Cardíaca/fisiopatología, Persona de Mediana Edad, Peptidil-Dipeptidasa A/genética, Polimorfismo Genético/genética
Preliminary study between Y chromosome haplogroups and chagasic cardiomyopathy manifestations in patients with Chagas disease
Rev. Soc. Bras. Med. Trop; 53 (), 2020
Abstract INTRODUCTION: Among patients with Chagas disease, men have a higher risk of worse pathological symptoms than women. We aimed to explore the role of the Y chromosome in men diagnosed with Chagas disease and assess the relationship between their ancestry and disease status. METHODS In this comp...
Triatomine bugs (Hemiptera, Reduviidae, Triatominae) in the Domiciles of the Guaribas Valley Territory, in Northeastern Brazil
Rev. Soc. Bras. Med. Trop; 53 (), 2020
Abstract INTRODUCTION Triatomine bugs are hematophagous insects that are extremely important in public health because they are natural vectors of Trypanosoma cruzi, the causative agent of Chagas disease. In this study, we aimed to assess the occurrence of triatomine species and the natural T. cruzi inf...
Epidemiological profile of acute Chagas disease in individuals infected by oral transmission in northern Brazil
Rev. Soc. Bras. Med. Trop; 53 (), 2020
Abstract INTRODUCTION: Oral infection by Trypanosoma cruzi is currently the most important route of transmission of acute Chagas disease (ACD) in the North region of Brazil, and the reported outbreaks are usually related to ingestion of contaminated food, especially unprocessed açaí pulp. METHODS A ...
The challenge of concomitant infections in the coronavirus disease 2019 pandemic era: Severe acute respiratory syndrome coronavirus 2 infection in a patient with chronic Chagas disease and dimorphic leprosy
Rev. Soc. Bras. Med. Trop; 53 (), 2020
Abstract Coronavirus disease 2019 (COVID-19) was first officially described in Brazil on February 26th, 2020. The accumulation of reports of concomitant infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and pathogens that cause diseases endemic to tropical countries, such as de...