Lopez-Lopez, Nallely;
Martinez, Ana Gabriela Ramos;
Garcia-Hernandez, Mariana Haydee;
Hernandez-Pando, Rogelio;
Castañeda-Delgado, Julio Enrique;
Lugo-Villarino, Geanncarlo;
Cougoule, Céline;
Neyrolles, Olivier;
Rivas-Santiago, Bruno;
Valtierra-Alvarado, Monica Alejandra;
Rubio-Caceres, Marisela;
Enciso-Moreno, Jose Antonio;
Serrano, Carmen Judith.
BACKGROUND Type 2 diabetes (T2D) is a risk factor for the development of tuberculosis (TB), although the associated mechanisms are not known. OBJECTIVES To study the association between T2D and the basal phenotype of macrophages, and their immune response to Mycobacterium tuberculosis (Mtb) infection....
Resumen Objetivo: Establecer las características clínicas, sociodemográficas y farmacológicas de pacientes con tuberculosis pulmonar. Metodología: Se realizó un estudio descriptivo, retrospectivo y de corte transversal con una muestra de 157 pacientes. La información se recolectó de la base d...
Background: Latent tuberculosis has been associated with the persistence of dormant Mycobacterium tuberculosis in the organism of infected individuals, who are reservoirs of the bacilli and the source for spreading the disease in the community. New active anti-TB drugs exerting their metabolic action at ...
ABSTRACT Objective: To analyze the impact that the 2009 changes in tuberculosis treatment in Brazil had on the rates of cure, tuberculosis recurrence, mortality, treatment abandonment, and multidrug-resistant tuberculosis (MDR-TB). Methods: An ordinary least squares regression model was used in order t...
Antituberculosos/uso terapéutico,
Brasil/epidemiología,
Notificación de Enfermedades,
Farmacorresistencia Bacteriana,
Análisis de Series de Tiempo Interrumpido,
Mycobacterium tuberculosis/efectos de los fármacos,
Factores de Riesgo,
Tuberculosis Resistente a Múltiples Medicamentos/tratamiento farmacológico,
Tuberculosis Resistente a Múltiples Medicamentos/mortalidad,
Tuberculosis Resistente a Múltiples Medicamentos/prevención & control,
Tuberculosis Pulmonar/tratamiento farmacológico,
Tuberculosis Pulmonar/mortalidad,
Tuberculosis Pulmonar/prevención & control
ABSTRACT Objective: To estimate the prevalence of and determine the risk factors associated with latent Mycobacterium tuberculosis infection (LTBI) among primary health care workers in the city of Vitória, Brazil. Methods: This was a cross-sectional study with data collected through a survey regarding...
Brasil/epidemiología,
Estudios Transversales,
Personal de Salud/estadística & datos numéricos,
Tuberculosis Latente/diagnóstico,
Tuberculosis Latente/epidemiología,
Tuberculosis Latente/microbiología,
Tuberculosis Latente/prevención & control,
Mycobacterium tuberculosis/aislamiento & purificación,
Enfermedades Profesionales/diagnóstico,
Enfermedades Profesionales/epidemiología,
Enfermedades Profesionales/microbiología,
Enfermedades Profesionales/prevención & control,
Prevalencia,
Factores de Riesgo,
Prueba de Tuberculina
Resumo:Tuberculose (TB) é uma doença infectocontagiosa que tem na forma pulmonar a maior importância clínica e epidemiológica.O Brasil apresenta alta incidência de TB, ocupando o 20º lugar no mundo e a situação entre as pessoas privadas de liberdade (PPL) é ainda mais grave. Por meio de pesquis...
Objectivo: Evaluar la utilidad de Anyplex™II_MTB/MDR/XDR para la detección de Mycobacterium tuberculosis y sensibilidad a medicamentos de primera y segunda línea, además del impacto en la conducta terapéutica en pacientes con sospecha de tuberculosis pulmonar atendidos en una institución de a...
BACKGROUND Mycobacterium tuberculosis (MTB) is one of the most significant causes of mortality and morbidity. Early diagnose is important especially in multiple drug resistant tuberculosis to avoid transmission. Traditional techniques requires at least one to three weeks for diagnosis of tuberculosis. Di...
Cytidine deaminase (MtCDA), encoded by cdd gene (Rv3315c), is the only enzyme identified in nucleotide biosynthesis pathway of Mycobacterium tuberculosis that is able to recycle cytidine and deoxycytidine. An M. tuberculosis knockout strain for cdd gene was obtained by allelic replacement. Evaluation of ...
Dantas, Nayanne Gama Teixeira;
Suffys, Phillip Noel;
Carvalho, Wânia da Silva;
Gomes, Harrison Magdinier;
Almeida, Isabela Neves de;
Figueiredo, Lida Jouca de Assis;
Gonçalves, Alan Douglas;
Gomgnimbou, Michel Kireopori;
Refregier, Guislaine;
Sola, Christophe;
Miranda, Silvana Spíndola de.
BACKGROUND The accurate detection of multidrug-resistant tuberculosis (MDR-TB) is critical for the application of appropriate patient treatment and prevention of transmission of drug-resistant Mycobacterium tuberculosis isolates. The goal of this study was to evaluate the correlation between phenotypic a...
