Results: 182

Drug resistance in Schistosomiasis: a review

Bruce, John I; Dias, Luiz Candido de Souza; Yung-San, Liang; Coles, Gerald C.

Mem. Inst. Oswaldo Cruz; 82 (supl.4), 1987

Drug resistance associated with the treatment of human schistosomiasis appears to be an emerging problem requiring more attention from the scientific community than the subject currently receives. Drug-resistant strains of Schistosoma mansoni have been isolated by various investigators as a result of lab...

Antihelmínticos/farmacología, Resistencia a Medicamentos/efectos de los fármacos, Esquistosomicidas/uso terapéutico, Schistosoma mansoni, Esquistosomiasis mansoni/transmisión

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The significance of variation in the susceptibility of Schistosoma mansoni to the antischistosomal drug oxamniquine

Kinoti, G. K.

Mem. Inst. Oswaldo Cruz; 82 (supl.4), 1987

Clinical and laboratory evidence is reviewed which shows that there is a great deal of variation in the susceptibility of Schistosoma mansoni to oxamniquine. This variation occurs both among endemic regions and within endemic regions in Brazil and Kenya. It is genetically controlled. It is suggested that...

Resistencia a Medicamentos, Nitroquinolinas/farmacología, Oxamniquina, Schistosoma mansoni/genética, Schistosoma mansoni/efectos de los fármacos, Resistencia a Medicamentos, Nitroquinolinas/farmacología, Oxamniquina, Schistosoma mansoni/genética, Schistosoma mansoni/efectos de los fármacos

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