Results: 3610

Treatment of patients with metastatic colorectal cancer and poor performance status: current evidence and challenges

Clinics; 73 (supl.1), 2018
Patients with unresectable metastatic colorectal cancer live for a median of three years when treated with standard therapies. While the evidence guiding cancer-directed treatment of this disease comes from phase III trials that have mostly enrolled patients with good performance status, some patients pr...

Survival and prognosis of young adults with gastric cancer

Clinics; 73 (supl.1), 2018
OBJECTIVES: Survival data for young adults (YA) with gastric cancer is conflicting and scarce in Brazil. The aim of this study was to compare the clinicopathological factors and survival rates of younger and older patients with gastric cancer. METHODS: Hospital registries for 294 gastric cancer patients...

Older adults with cancer in the city of São Paulo: what factors determine the place of death?

ABSTRACT OBJECTIVE Investigate factors associated with death at home among older adults who died of cancer in a large city. METHODS This is a descriptive study, including all cancer deaths (ICD C00-C97) occurring between 2006 and 2012, among residents of the city of São Paulo, 60 years of age or old...

Burden of ischemic heart disease mortality attributable to physical inactivity in Brazil

ABSTRACT OBJECTIVE To analyze if the burden of ischemic heart disease mortality trend attributed to physical inactivity in Brazil differs from the global estimates. METHODS Databases from the Global Burden of Disease Study for Brazil, Brazilian states, and global information were used. We estimated t...

Advances in Mexico in the middle of the decade of action for road safety 2011-2020

ABSTRACT OBJECTIVE To analyze the progress towards the accomplishment of the expected goal in the middle of the Decade of Action for Road Safety 2011-2020 in Mexico and its states. METHODS This is a secondary analysis of road traffic deaths in Mexico between 1999 and 2015. We projected the trend for ...

Hospital mortality in older patients in the Brazilian Unified Health System, Southeast region

ABSTRACT OBJECTIVE To evaluate factors associated with hospital death in older inpatients for specific diseases of the circulatory system in the Brazilian Unified Health System considering the risk-adjusted hospital mortality as an indicator of effectiveness. METHODS The data were extracted from the ...

Impact of discharge medication counseling in the cardiology unit of a tertiary hospital in Brazil: A randomized controlled trial

Clinics; 73 (), 2018
OBJECTIVES: This study aimed to evaluate the impact of pharmacist-provided discharge counseling on mortality rate, hospital readmissions, emergency department visits, and medication adherence at 30 days post discharge. METHODS: This randomized controlled trial was approved by the local ethics committee ...

Burkholderia cepacia, cystic fibrosis and outcomes following lung transplantation: experiences from a single center in Brazil

Clinics; 73 (), 2018
OBJECTIVES: To evaluate the impact of Burkholderia cepacia complex colonization in cystic fibrosis patients undergoing lung transplantation. METHODS: We prospectively analyzed clinical data and respiratory tract samples (sputum and bronchoalveolar lavage) collected from suppurative lung disease patients...

Comorbidities increase in-hospital mortality in dengue patients in Brazil

Mem. Inst. Oswaldo Cruz; 113 (8), 2018
Dengue remains an unmet public health burden. We determined risk factors for dengue in-hospital mortality in Brazil. Of 326,380 hospitalised dengue cases in 9-45-year-old individuals, there were 971 deaths. Risk of dying was 11-times higher in the presence of underlying common comorbidities (renal, infec...

En bloc vertebrectomy for the treatment of spinal lesions. Five years of experience in a single institution: a case series

Clinics; 73 (), 2018
OBJECTIVES: The objective of this study is to describe the experience of a Brazilian public university hospital regarding the treatment of metastatic or benign spine lesions with en bloc vertebrectomy of the thoracic and lumbar spines. METHODS: This study was a retrospective case series and included all...