Results: 3275

[RETRACTED ARTICLE] Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis

Braz. j. med. biol. res; 51 (2), 2018
Caspase recruitment domain-containing protein 9 (Card9) is located upstream of the nuclear factor kappa B (NF-κB) and p38 mitogen-activated protein kinase (MAPK) inflammatory pathways. This study investigated the therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pa...

Characterization of air-liquid interface culture of A549 alveolar epithelial cells

Braz. j. med. biol. res; 51 (2), 2018
Alveolar epithelia play an essential role in maintaining the integrity and homeostasis of lungs, in which alveolar epithelial type II cells (AECII) are a cell type with stem cell potential for epithelial injury repair and regeneration. However, mechanisms behind the physiological and pathological roles o...

Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage

Braz. j. med. biol. res; 51 (2), 2018
Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has been widely reported to exert anti-inflammatory actions. This study aimed to reveal whether ginsenoside Rg1 also exhibits beneficial roles against lipopolysaccharide (LPS)-induced apoptosis and inflammation in human renal tu...

Specific questionnaire detects a high incidence of intra-operative hypersensitivity reactions

Clinics; 73 (), 2018
OBJECTIVE: To assess the incidence of intra-operative immediate hypersensitivity reactions and anaphylaxis. METHODS: A cross-sectional observational study was conducted at the Department of Anesthesiology, University of São Paulo School of Medicine, Hospital das Clínicas, São Paulo, Brazil, from Janu...

Standardization of a spinal cord lesion model and neurologic evaluation using mice

Clinics; 73 (), 2018
OBJECTIVE: To standardize a spinal cord lesion mouse model. METHODS: Thirty BALB/c mice were divided into five groups: four experimental groups and one control group (sham). The experimental groups were subjected to spinal cord lesion by a weight drop from different heights after laminectomy whereas the...

Evidence of validity of the stress-producing life events (SPLE) instrument

ABSTRACT OBJECTIVE Evaluate the construct validity of a list of eight Stressful Life Events in pregnant women. METHODS A cross-sectional study was conducted with 1,446 pregnant women in São Luís, MA, and 1,364 pregnant women in Ribeirão Preto, SP (BRISA cohort), from February 2010 to June 2011. In...

Autoeficacia cuestionario de autorregulación de estudio readiness

Aval. psicol; 17 (1), 2018
La investigación ha demostrado la importancia de los instrumentos que miden la autoeficacia ligada a áreas de funcionamiento diferenciado, como el aprendizaje autorregulado. El objetivo de este trabajo fue proyectar y estudiar el comportamiento psicométrico del Cuestionario de Autoeficacia para la Aut...

El esquema de triterapia de 14 días es superior al esquema de 10 días para la erradicación de Helicobacter pylori: un estudio canadiense realizado en un escenario “realista”

Gastroenterol. latinoam; 29 (1), 2018

Eficacia del sulfato de zinc en el tratamiento de la úlcera péptica: un estudio clínico randomizado doble ciego

Gastroenterol. latinoam; 29 (4), 2018

Association between quality of life and prognosis of candidate patients for heart transplantation: a cross-sectional study

ABSTRACT Objective: to verify the association between the prognostic scores and the quality of life of candidates for heart transplantation. Method: a descriptive cross-sectional study with a convenience sample of 32 outpatients applying to heart transplantation. The prognosis was rated by the Heart Fa...