Results: 22659

Frequency of ponticulus posticus in lateral cephalometric radiography of peruvian patients

Int. j. morphol; 32 (1), 2014
The Ponticulus posticus is an anomalous ossification of unknown origin that arches backward from the superior articular process to the posterior arch of the Atlas vertebra, it can be complete or partial and houses vascular and nervous elements; it is diagnosed by lateral cervical radiography, cephalometr...

Application of a more advanced procedure in defining morphological types

Int. j. morphol; 32 (1), 2014
It is well known that the most evident differences in humans are those related to anthropometric characteristics, and that during continuous monitoring the relation between human behavior and human abilities concerning their anthropometric characteristics was observed. The aim of this study was to detect...

Statistical approaches for analyzing a continuous outcome in experimental studies

Int. j. morphol; 32 (1), 2014
In experimental studies the outcome variable is measured at initial time, usually called "baseline", and then in several times called "follow-up" measurement(s). The study question of interest in an experimental study is whether there is a significant difference effect between treatment and comparison gr...

Bone augmentation with occlusive barriers and cortical particulate allograft in transverse maxillary defects: a pilot study

Int. j. morphol; 32 (1), 2014
The centripetal resorption of maxilla is a continuous process after tooth loss. For treatment of deficient bone sites, autologous bone grafts may be used, as an alternative, biomaterials can be applied which do not require intra or extraoral donor sites. The present report describes the use of occlusive ...

A study on enhanced intestinal permeability of clarithromycin nanoparticles

Braz. j. pharm. sci; 50 (1), 2014
The main objective of the present study was to determine the permeability of clarithromycin (CLA)-PLGA nanoparticles using single-pass intestinal perfusion technique in rats. Clarithromycin nanoparticles were prepared by nano-precipitation according to the modified quasi emulsion solvent diffusion techni...

Development and optimization of self microemulsifying drug delivery of domperidone

Braz. j. pharm. sci; 50 (1), 2014
The present investigation is aimed to develop self-microemulsifying drug delivery system (SMEDDS) to improve the in vitro dissolution of a BCS (Biopharmaceutical Classification System) class II anti emetic agent, domperidone. Solubility study was performed to identify the ingredients showing highest solu...

Anticonvulsant profile of 2-ethylthio-7-methyl-4-(4-methylphenyl)pyrazolo[1, 5-a][1, 3, 5]triazine

Braz. j. pharm. sci; 50 (1), 2014
This work evaluates the central nervous effects in ICR strain mice of 2-ethylthio-7-methyl-4-(4-methylphenyl)pyrazolo[1,5-a][1,3,5]triazine (MH4b1), a compound obtained by an efficient one-step reaction of S,S-diethyl 4-methylbenzoylimidodithiocarbonate with 5-amino-3-methyl-1H-pyrazole, in order to asse...

pH-sensitive polyvinylpyrrolidone-acrylic acid hydrogels: Impact of material parameters on swelling and drug release

Braz. j. pharm. sci; 50 (1), 2014
In this study, we fabricated pH-sensitive polyvinylpyrrolidone/acrylic acid (PVP/AA) hydrogels by a free-radical polymerisation method with variation in the content of monomer, polymer and cross-linking agent. Swelling was performed in USP phosphate buffer solutions of pH 1.2, 5.5, 6.5 and 7.5 with const...

Chemical constituents and pharmacological profile of Gunnera manicata L. extracts

Braz. j. pharm. sci; 50 (1), 2014
Gunnera perpensa L. (Gunneraceae) is a native South African plant widely used in traditional medicine as an antibacterial and antifungal. In southern Brazil there is the native species called Gunnera manicata L. that also belongs to the Gunneraceae. Nevertheless, there is no information about chemical an...

Validation of analytical methodology for quantification of cefazolin sodium pharmaceutical dosage form by high performance liquid chromatography to be applied for quality control in pharmaceutical industry

Braz. j. pharm. sci; 50 (1), 2014
A reversed-phase high performance liquid chromatography method was validated for the determination of cefazolin sodium in lyophilized powder for solution for injection to be applied for quality control in pharmaceutical industry. The liquid chromatography method was conducted on a Zorbax Eclipse Plus C18...