Background: Diabetes mellitus type 1 (T1DM) is one of the childhood diseases with growing prevalence. Various accompanying autoimmune diseases were seen with type 1 diabetes. The most common autoimmune diseases with T1DM are autoimmune thyroiditis and celiac disease. In some reports, autoimmune hepatitis...
AutoanticuerposSangre,
Diabetes Mellitus Tipo 1/inmunología,
Hepatitis Autoinmune/inmunología,
Alanina TransaminasaSangre,
Anticuerpos AntinuclearesSangre,
Aspartato AminotransferasasSangre,
Estudios Transversales,
Riñón/inmunología,
Microsomas/inmunología,
Microsomas Hepáticos/inmunología,
Músculo Liso/inmunología
ABSTRACT BACKGROUND: Indigofera suffruticosa Mill (Fabaceae) is abundant in northeastern Brazil and popularly used in the treatment of infectious and inflammatory processes. Several biological properties, such as anti-inflammatory, anticancer, antitumor, hepatoprotective and low toxicity, are reported f...
Abstract Objective: To describe the demographic, clinical, laboratory and molecular characteristics of patients with lysosomal acid lipase deficiency. Methods: A retrospective review of the medical records of children with the disease. Results: Seven children with lysosomal acid lipase deficiency (5 m...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Aspartato Aminotransferasas/sangre,
Biopsia,
Brasil,
Colesterol/sangre,
Dislipidemias/patología,
Hepatomegalia/patología,
Hígado/patología,
Registros Médicos,
Estudios Retrospectivos,
Triglicéridos/sangre,
Enfermedad de Wolman/patología
Abstract Background Irisin is a protein cleaved from fibronectin type III domain-containing protein 5 and has been implicated in the beneficial effects of exercise. However, it is unknown which factors contribute to irisin increment after intensive exercising in humans. This study aimed to assess indepe...
Alanina Transaminasa/sangre,
Glucemia/metabolismo,
Índice de Masa Corporal,
Ejercicio Físico/fisiología,
Prueba de Esfuerzo,
Factores de Crecimiento de Fibroblastos/sangre,
Fibronectinas/sangre,
Insulina/sangre,
Estudios Longitudinales,
Estudios Prospectivos,
Conducta Sedentaria
Abstract BACKGROUND: Tacrolimus, for its activity on modulation of collagen production and fibroblast activity, may have a role in the prevention of hypertrophic scars. OBJECTIVES: Evaluate macroscopic, microscopic, metabolic, laboratory effects and side effects of the use of topical tacrolimus ointmen...
Administración Tópica,
Alanina Transaminasa/sangre,
Alanina Transaminasa/efectos de los fármacos,
Inhibidores de la Calcineurina/administración & dosificación,
Inhibidores de la Calcineurina/farmacología,
Inhibidores de la Calcineurina/uso terapéutico,
Cicatriz Hipertrófica/patología,
Cicatriz Hipertrófica/prevención & control,
Creatinina/sangre,
Modelos Animales de Enfermedad,
Oído Externo/patología,
Eritema/patología,
Inflamación/patología,
Inflamación/prevención & control,
Recuento de Linfocitos,
Pomadas,
Albúmina Sérica/análisis,
Albúmina Sérica/efectos de los fármacos,
Tacrolimus/administración & dosificación,
Tacrolimus/farmacología,
Tacrolimus/uso terapéutico,
Urea/sangre
ABSTRACT OBJECTIVE Describe the clinical and epidemiological profile of confirmed cases of yellow fever whose patients were hospitalized in a general hospital for infectious diseases in the State of Rio de Janeiro, Brazil, from March 11, 2017 to June 15, 2018, during a recent outbreak and factors assoc...
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Bilirrubina/sangre,
Brasil/epidemiología,
Creatinina/sangre,
Brotes de Enfermedades/estadística & datos numéricos,
Mortalidad Hospitalaria,
Modelos Logísticos,
Persona de Mediana Edad,
Análisis Multivariante,
Valores de Referencia,
Estudios Retrospectivos,
Factores de Riesgo,
Estadísticas no Paramétricas,
Factores de Tiempo,
Urea/sangre,
Fiebre Amarilla/sangre,
Fiebre Amarilla/mortalidad
Abstract INTRODUCTION: IgG subclasses involved in the immune response to hepatitis C virus (HCV) antigens have been rarely studied. We investigated the immune response mediated by IgG1 and IgG4 antibodies against the recombinant core and NS3 antigens in patients with chronic hepatitis C. METHODS: Six...
Alanina Transaminasa/sangre,
Estudios de Casos y Controles,
Crioglobulinemia,
Ensayo de Inmunoadsorción Enzimática,
Hepacivirus/inmunología,
Anticuerpos contra la Hepatitis C/sangre,
Anticuerpos contra la Hepatitis C/inmunología,
Antígenos de la Hepatitis C/sangre,
Antígenos de la Hepatitis C/inmunología,
Hepatitis C Crónica/sangre,
Hepatitis C Crónica/inmunología,
Inmunoglobulina G/sangre,
Cirrosis Hepática/virología,
Persona de Mediana Edad,
Valores de Referencia,
Estadísticas no Paramétricas,
Carga Viral,
Viremia
Abstract Purpose Coleus forskohlii Briq., a medicinal plant originally from India, has been indicated against heart disease, expiratory disorders, convulsions, and hepatic changes, among others. In view of the broad pharmacological potential of the plant and the scarce information about its effects, the...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Aspartato Aminotransferasas/sangre,
Biomarcadores/sangre,
Hepatectomía/métodos,
Hepatocitos/efectos de los fármacos,
Hiperplasia/tratamiento farmacológico,
Hígado/efectos de los fármacos,
Hígado/patología,
Hígado/cirugía,
Extractos Vegetales/administración & dosificación,
Plectranthus/química
Bone marrow mesenchymal stem cells (BMSCs) transplantation has attracted attention for the treatment of liver cirrhosis and end-stage liver diseases. Therefore, in this study, we evaluated the effect of different methods of BMSCs transplantation in the treatment of liver cirrhosis in rats. Seventy-two ma...
Abstract Purpose To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury Methods Fifty-one Wistar rats were randomly grouped into sham, I/R, and sevoflurane groups. After reperfusion, the structural change of the lung was measured by Smi...
Alanina Transaminasa/sangre,
Anestésicos por Inhalación/uso terapéutico,
Aspartato Aminotransferasas/sangre,
Modelos Animales de Enfermedad,
Isquemia/prevención & control,
Precondicionamiento Isquémico/métodos,
Hígado/irrigación sanguínea,
Hígado/efectos de los fármacos,
Hígado/patología,
Pulmón/irrigación sanguínea,
Pulmón/efectos de los fármacos,
Pulmón/patología,
Malondialdehído/análisis,
Peroxidasa/análisis,
Daño por Reperfusión/tratamiento farmacológico,
Daño por Reperfusión/prevención & control,
Sevoflurano/uso terapéutico,
Factor de Necrosis Tumoral alfa/sangre
