Results: 27

Uso de testosterona en mujeres: un comentario sobre el consenso global sobre el uso de la terapia de testosterona para mujeres
Global consensus position statement on the use of testosterone therapy for women

Las mujeres han sido tratadas por décadas con testosterona intentando aliviar una gran variedad de síntomas con riesgos y beneficios inciertos. En la mayoría de los países, la testosterona se prescribe “off-label”, de modo que las mujeres están utilizando compuestos y dosis ideadas para tratamie...

Salud ósea en personas transgénero
Bone health in transgender subjects

Actual. osteol; 16 (3), 2020
Una persona transgénero es aquella en la cual el género autopercibido difiere del asignado al nacer, mientras que el término cisgénero es utilizado en aquellos individuos no trans. El tratamiento hormonal cruzado (THC) constituye una opción para lograr caracteres sexuales secundarios deseados. Es co...

Síndrome de Insensibilidad Completa a Andrógenos (SICA): reporte de un caso clínico

Rev. méd. Maule; 34 (2), 2019
INTRODUCTION: Complete Androgen Insensitivity Syndrome (CAIS) is a X-linked recessive disorder characterized by a complete resistance of the Androgen Receptor (AR) to androgens. As a result, affected individuals present complete female external genitalia, but are genetically male with a 46, XY karyotype....

Síndrome dos ovários policísticos: tratamento das manifestações androgênicas

Femina; 47 (9), 2019
A síndrome dos ovários policísticos (SOP) é um distúrbio endócrino-metabólico muito frequente no período reprodutivo. Quando associado ao distúrbio metabólico, as mulheres com SOP podem ter ainda risco acrescido para doença cardiovascular. O objetivo deste manuscrito é descrever as repercuss...

Enhancing PSMA-uptake with androgen deprivation therapy - a new way to detect prostate cancer metastases?

Int. braz. j. urol; 45 (3), 2019
ABSTRACT Purpose: 68Ga-PSMA PET/CT imaging is a promising modality for the staging of recurrent prostate cancer (PCa). Current evidence suggests limited diagnostic value of the 68Ga-PSMA PET/CT in PSA-levels ≤0.3ng/mL. Experimental data have demonstrated an increase in PSMA-expression in PCa metas...

Supposed pituitary-production of human chorionic Gonadotropin induced by androgen deprivation therapy

Int. braz. j. urol; 45 (1), 2019
ABSTRACT Introduction: The main cause of slightly elevated human chorionic gonadotropin (HCG) after successful treatment of male germ cell tumors is considered to be pituitary-derived HCG. It is well known that pituitary-derived HCG is frequently detected in postmenopausal women. We evaluated the status...

Cost-effectiveness analysis of abiraterone, docetaxel or placebo plus androgen deprivation therapy for hormone-sensitive advanced prostate cancer

Einstein (Säo Paulo); 17 (2), 2019
ABSTRACT Objective To evaluate the cost-effectiveness of the addition of chemotherapy or abiraterone to androgen deprivation. Methods We developed an analytical model to determine the cost-effectiveness of the addition of docetaxel or abiraterone versus androgen deprivation therapy alone. Direct and ...

Low estrogen doses normalize testosterone and estradiol levels to the female range in transgender women

Clinics; 73 (), 2018
OBJECTIVE: The ideal dosage of cross-sex hormones remains unknown. The aim of this study was to evaluate the luteinizing hormone, follicle-stimulating hormone, testosterone, estradiol and prolactin levels after low-dose estrogen therapy with or without cyproterone acetate in transgender women. METHODS: ...

Informe de evaluación científica basada en la evidencia disponible: cáncer de próstata
Scientific evaluation report based on available evidence: prostate cancer

INTRODUCCIÓN: El cáncer de próstata es uno de los tumores sólidos más frecuentes en hombres en el mundo, siendo el más incidente en Europa con una tasa de 214 casos por cada 1000 hombres, superando al cáncer de pulmón y colorrectal. En Chile, el cáncer de próstata se ubica como la segunda causa...