Results: 30

Characterization of clinical isolates of Mycobacterium tuberculosis from indigenous peoples of Colombia

Biomédica (Bogotá); 39 (supl.2), 2019
ABSTRACT Introduction: Tuberculosis continues to be a public health priority. Indigenous peoples are vulnerable groups with cultural determinants that increase the risk of the disease. Objective: To determine molecular epidemiology and phenotypical features and of Mycobacterium tuberculosis isolates fr...

Perfil dos municípios brasileiros, a presença de tuberculose e sua forma drogarresistente

Resumo A tuberculose tem estreita relação com as condições de vida das pessoas. O presente estudo classifica os municípios brasileiros de acordo com a presença ou ausência de casos de tuberculose (TB) e sua forma drogarresistente (TB-DR), e os descreve quanto às condições de saúde da populaç�...

Vigilancia por el laboratorio de la tuberculosis resistente en menores de 15 años, Colombia, 2010 a 2015

Biomédica (Bogotá); 39 (2), 2019
Resumen Introducción. La tuberculosis en los niños es un reflejo de transmisión reciente en la comunidad. Se estima que en el mundo cada año un millón de niños enferma por esta causa; en Colombia se notificaron 291 casos en el 2015. Objetivo. Actualizar la información obtenida de las actividades...

Speeding up the diagnosis of multidrug-resistant tuberculosis in a high-burden region with the use of a commercial line probe assay

J. bras. pneumol; 45 (2), 2019
ABSTRACT Objective: To evaluate the rapid diagnosis of multidrug-resistant tuberculosis, by using a commercial line probe assay for rifampicin and isoniazid detection (LPA-plus), in the routine workflow of a tuberculosis reference laboratory. Methods: The LPA-plus was prospectively evaluated on 341 iso...

Tuberculosis por Mycobacterium africanum multirresistente: Caso clinico pediatrico

Arch. argent. pediatr; 116 (3), 2018
La tuberculosis, considerada desde 2003 por la Organización Mundial de la Salud una emergencia global de salud, provoca una mortalidad anual de alrededor de 2 millones de personas, fundamentalmente, en países en vías de desarrollo. En la población pediátrica española, la incidencia es de 5 casos/10...

In vitro anti-tuberculosis activity of azole drugs against Mycobacterium tuberculosis clinical isolates

Rev. argent. microbiol; 49 (4), 2017
Background: Latent tuberculosis has been associated with the persistence of dormant Mycobacterium tuberculosis in the organism of infected individuals, who are reservoirs of the bacilli and the source for spreading the disease in the community. New active anti-TB drugs exerting their metabolic action at ...

Natural Compounds from Mexican Medicinal Plants as Potential Drug Leads for Anti-Tuberculosis Drugs

An. acad. bras. ciênc; 89 (1), 2017
ABSTRACT In Mexican Traditional Medicine 187 plant species are used in the treatment of respiratory conditions that may be associated with tuberculosis. In this contribution, we review the ethnobotany, chemistry and pharmacology of 63 species whose extracts have been assayed for antimycobacterial activit...

Detection of multidrug-resistant Mycobacterium tuberculosis strains isolated in Brazil using a multimarker genetic assay for katG and rpoB genes

Braz. j. infect. dis; 20 (2), 2016
Abstract Multidrug-resistant tuberculosis (MDRTB) is a serious world health problem that limits public actions to control tuberculosis, because the most used anti-tuberculosis first-line drugs fail to stop mycobacterium spread. Consequently, a quick detection through molecular diagnosis is essential to r...

Primary drug resistance in a region with high burden of tuberculosis: A critical problem

Salud pública Méx; 57 (2), 2015
Objective. To determine rates of drug resistance in new cases of pulmonary tuberculosis in a region with a high burden of the disease. Materials and methods. New case suspects were referred for drug susceptibility testing. Results. 28.9% of new cases were resistant to at least one first line drug; 3.9% h...

Detection of drug resistant Mycobacterium tuberculosis among patients with and without HIV infection in a rural setting

West Indian med. j; 62 (2), 2013
OBJECTIVE: To analyse the sensitivity of Mycobacterium tuberculosis by nitrate reductase assay (NRA) and the Hain molecular line probe assay (LPA) in sputa of tuberculosis (TB)/HIV co-infected patients in Guyana. DESIGN: Sputum samples were collected from known TB patients at Georgetown Chest Clinic and ...