ABSTRACT BACKGROUND: Indigofera suffruticosa Mill (Fabaceae) is abundant in northeastern Brazil and popularly used in the treatment of infectious and inflammatory processes. Several biological properties, such as anti-inflammatory, anticancer, antitumor, hepatoprotective and low toxicity, are reported f...
RESUMEN El médico asistencial debe evaluar a diario las pruebas hepáticas en personas con afecciones del hígado, o en los llamados controles a personas supuestamente normales. El objetivo fue facilitar la reflexión práctica en la interpretación de las pruebas hepáticas. Se realizó una revisión d...
Abstract Objective: To describe the demographic, clinical, laboratory and molecular characteristics of patients with lysosomal acid lipase deficiency. Methods: A retrospective review of the medical records of children with the disease. Results: Seven children with lysosomal acid lipase deficiency (5 m...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Aspartato Aminotransferasas/sangre,
Biopsia,
Brasil,
Colesterol/sangre,
Dislipidemias/patología,
Hepatomegalia/patología,
Hígado/patología,
Registros Médicos,
Estudios Retrospectivos,
Triglicéridos/sangre,
Enfermedad de Wolman/patología
ABSTRACT OBJECTIVE Describe the clinical and epidemiological profile of confirmed cases of yellow fever whose patients were hospitalized in a general hospital for infectious diseases in the State of Rio de Janeiro, Brazil, from March 11, 2017 to June 15, 2018, during a recent outbreak and factors assoc...
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Bilirrubina/sangre,
Brasil/epidemiología,
Creatinina/sangre,
Brotes de Enfermedades/estadística & datos numéricos,
Mortalidad Hospitalaria,
Modelos Logísticos,
Persona de Mediana Edad,
Análisis Multivariante,
Valores de Referencia,
Estudios Retrospectivos,
Factores de Riesgo,
Estadísticas no Paramétricas,
Factores de Tiempo,
Urea/sangre,
Fiebre Amarilla/sangre,
Fiebre Amarilla/mortalidad
Abstract Purpose Coleus forskohlii Briq., a medicinal plant originally from India, has been indicated against heart disease, expiratory disorders, convulsions, and hepatic changes, among others. In view of the broad pharmacological potential of the plant and the scarce information about its effects, the...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Aspartato Aminotransferasas/sangre,
Biomarcadores/sangre,
Hepatectomía/métodos,
Hepatocitos/efectos de los fármacos,
Hiperplasia/tratamiento farmacológico,
Hígado/efectos de los fármacos,
Hígado/patología,
Hígado/cirugía,
Extractos Vegetales/administración & dosificación,
Plectranthus/química
Bone marrow mesenchymal stem cells (BMSCs) transplantation has attracted attention for the treatment of liver cirrhosis and end-stage liver diseases. Therefore, in this study, we evaluated the effect of different methods of BMSCs transplantation in the treatment of liver cirrhosis in rats. Seventy-two ma...
Abstract Purpose: To investigate the prognostic value of 17 platelet-based prognostic scores in patients with malignant hepatic tumors after TACE therapy. Methods: In total, 92 patients were divided into death group and survival group according to long-term follow-up results. The AUC was calculated to ...
Aspartato Aminotransferasas/sangre,
Biomarcadores de Tumor/sangre,
Plaquetas/química,
Carcinoma Hepatocelular/sangre,
Carcinoma Hepatocelular/mortalidad,
Carcinoma Hepatocelular/terapia,
Quimioembolización Terapéutica/métodos,
Estimación de Kaplan-Meier,
Neoplasias Hepáticas/sangre,
Neoplasias Hepáticas/mortalidad,
Neoplasias Hepáticas/terapia,
Recuento de Plaquetas,
Pronóstico,
Curva ROC,
Estudios Retrospectivos
Abstract Purpose To investigate the effect of sevoflurane preconditioning on ischemia/reperfusion (I/R)-induced pulmonary/hepatic injury Methods Fifty-one Wistar rats were randomly grouped into sham, I/R, and sevoflurane groups. After reperfusion, the structural change of the lung was measured by Smi...
Alanina Transaminasa/sangre,
Anestésicos por Inhalación/uso terapéutico,
Aspartato Aminotransferasas/sangre,
Modelos Animales de Enfermedad,
Isquemia/prevención & control,
Precondicionamiento Isquémico/métodos,
Hígado/irrigación sanguínea,
Hígado/efectos de los fármacos,
Hígado/patología,
Pulmón/irrigación sanguínea,
Pulmón/efectos de los fármacos,
Pulmón/patología,
Malondialdehído/análisis,
Peroxidasa/análisis,
Daño por Reperfusión/tratamiento farmacológico,
Daño por Reperfusión/prevención & control,
Sevoflurano/uso terapéutico,
Factor de Necrosis Tumoral alfa/sangre
Abstract Purpose: To establish a new rat model, the pathogenesis of which is closer to the clinical occurrence of chronic obstructive jaundice with liver fibrosis. Methods: 90 SD rats were randomly divided into 3 groups. Group A common bile duct ligation, group B common bile duct injection compont and ...
Aspartato Aminotransferasas/sangre,
Fosfatasa Alcalina/sangre,
Compuestos Azo,
Conductos Biliares/efectos de los fármacos,
Conductos Biliares/patología,
Bilirrubina/análisis,
Modelos Animales de Enfermedad,
Ensayo de Inmunoadsorción Enzimática,
Eosina Amarillenta-(YS),
Geles/administración & dosificación,
Inmunohistoquímica,
Inyecciones,
Ictericia Obstructiva/inducido químicamente,
Ictericia Obstructiva/patología,
Cirrosis Hepática/inducido químicamente,
Cirrosis Hepática/patología,
Verde de Metilo,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Valores de Referencia,
Reproducibilidad de los Resultados,
Albúmina Sérica/análisis,
Factores de Tiempo,
gamma-Glutamiltransferasa/sangre
Abstract INTRODUCTION Portal hypertension and periportal fibrosis commonly occur in severe Schistosoma mansoni infection. Changes in lipid profile and elevated levels of circulating liver enzymes have also been described in infected individuals. The present study sought to assess the alterations in lab...
Alanina Transaminasa/sangre,
Fosfatasa Alcalina/sangre,
Aspartato Aminotransferasas/sangre,
Heces/parasitología,
Lípidos/sangre,
Schistosoma mansoni/aislamiento & purificación,
Esquistosomiasis mansoni/sangre,
Esquistosomiasis mansoni/diagnóstico,
Esquistosomiasis mansoni/enzimología,
gamma-Glutamiltransferasa/sangre,
Biomarcadores/sangre
